Bence Paul

New Reference Materials, Analytical Procedures and Data Reduction Strategies for Sr Isotope Measurements in Geological Materials by LA-MC-ICP-MS

J Mulder, G Hagen-Peter, T Ubide, R Andreasen, E Kooijman, M Kielman-Schmitt, YX Feng, B Paul, A Karlsson, C Tegner, C Lesher, F Costa

Journal article  |  2023  |  Geostandards and Geoanalytical Research

Laser ablation multi-collector mass spectrometry (LA-MC-ICP-MS) has emerged as the technique of choice for in situ measurements of..

An integrated mass spectrometry imaging and digital pathology workflow for objective detection of colorectal tumours by unique atomic signatures

Bence Paul, Kai Kysenius, James B Hilton, Michael WM Jones, Robert W Hutchinson, Daniel D Buchanan, Christophe Rosty, Fred Fryer, Ashley Bush, Janet M Hergt, Jon D Woodhead, David P Bishop, Philip A Doble, Michelle M Hill, Peter J Crouch, Dominic J Hare

Journal article  |  2021  |  CHEMICAL SCIENCE

Tumours are abnormal growths of cells that reproduce by redirecting essential nutrients and resources from surrounding tissue. Cha..

Reply to: Clusters of flowstone ages are not supported by statistical evidence

Robyn Pickering, Andy IR Herries, Jon D Woodhead, John C Hellstrom, Helen E Green, Bence Paul, Terrence Ritzman, David S Strait, Benjamin J Schoville, John Hancox

Journal article  |  2021  |  NATURE

Disrupted copper availability in sporadic ALS: Implications for CuII(atsm) as a treatment option

James BW Hilton, Kai Kysenius, Jeffrey Liddell, Carsten Rautengarten, Stephen Mercer, Bence Paul, Joseph Beckman, Catriona McLean, Anthony White, Paul Donnelly, Ashley Bush, Dominic Hare, Blaine Roberts, Peter Crouch

Journal article  |  2020

ABSTRACT Objective The copper compound Cu II (atsm) is in phase 2/3 testing for treatment of the neurodegenerative disease amyotro..

Construction of 3D native elemental maps for large biological specimens using LA-ICP-MS coupled with X-ray tomography

Estephany Marillo-Sialer, Jay R Black, Bence Paul, Kai Kysenius, Peter J Crouch, Janet M Hergt, Jon D Woodhead, Dominic J Hare

Journal article  |  2020  |  JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

A step-change in the utility of elemental imaging in the biological sciences can be achieved by the integration of quantitative el..

Partitioning of Mg, Sr, Ba and U into a subaqueous calcite speleothem

Russell N Drysdale, Giovanni Zanchetta, Ilaria Baneschi, Massimo Guidi, Ilaria Isola, Isabelle Couchoud, Leonardo Piccini, Alan Greig, Henri Wong, Jon D Woodhead, Eleonora Regattieri, Ellen Corrick, Bence Paul, Christoph Spotl, Eleonor Denson, Jay Gordon, Stephane Jaillet, Florian Dux, John C Hellstrom

Journal article  |  2019  |  GEOCHIMICA ET COSMOCHIMICA ACTA

The trace-element geochemistry of speleothems is becoming increasingly used for reconstructing palaeoclimate, with a particular em..

U-Pb-dated flowstones restrict South African early hominin record to dry climate phases

Robyn Pickering, Andy IR Herries, Jon D Woodhead, John C Hellstrom, Helen E Green, Bence Paul, Terrence Ritzman, David S Strait, Benjamin J Schoville, Phillip J Hancox

Journal article  |  2019  |  NATURE

The Cradle of Humankind (Cradle) in South Africa preserves a rich collection of fossil hominins representing Australopithecus, Par..

A versatile quantitative microdroplet elemental imaging method optimised for integration in biochemical workflows for low-volume samples

Kai Kysenius, Bence Paul, James B Hilton, Jeffrey R Liddell, Dominic J Hare, Peter J Crouch

Journal article  |  2019  |  ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) analysis of μ-droplets is becoming an attractive alternati..

Anatomical redistribution of endogenous copper in embryonic mice overexpressing SOD1

K Kysenius, JB Hilton, B Paul, DJ Hare, PJ Crouch

Journal article  |  2019  |  METALLOMICS

Mutations in the copper (Cu)- and zinc (Zn)-binding metalloenzyme Cu/Zn-superoxide dismutase (SOD1) cause familial forms of amyotr..

Whole-brain metallomic analysis of the common marmoset (Callithrix jacchus)

B Knauer, P Majka, KJ Watkins, AWR Taylor, D Malamanova, B Paul, Hsin-Hao Yu, AI Bush, DJ Hare, DH Reser

Journal article  |  2017  |  METALLOMICS

Despite the importance of transition metals for normal brain function, relatively little is known about the distribution of these ..