Janet Keast

Computational modeling of endovascular peripheral nerve stimulation using a stent-mounted electrode array.

JingYang Liu, David B Grayden, Janet R Keast, Sam E John

Journal article  |  2022  |  J Neural Eng

OBJECTIVE: Endovascular neuromodulation has attracted substantial interest in recent years as a minimally invasive approach to tre..

Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems

Xinhong Chen, Sripriya Ravindra Kumar, Cameron D Adams, Daping Yang, Tongtong Wang, Damien A Wolfe, Cynthia M Arokiaraj, Victoria Ngo, Lillian J Campos, Jessica A Griffiths, Takako Ichiki, Sarkis K Mazmanian, Peregrine B Osborne, Janet R Keast, Cory T Miller, Andrew S Fox, Isaac M Chiu, Viviana Gradinaru

Journal article  |  2022  |  NEURON

Gene therapy offers great promise in addressing neuropathologies associated with the central and peripheral nervous systems (CNS a..

High-throughput segmentation of unmyelinated axons by deep learning

Emanuele Plebani, Natalia P Biscola, Leif A Havton, Bartek Rajwa, Abida Sanjana Shemonti, Deborah Jaffey, Terry Powley, Janet R Keast, Kun-Han Lu, M Murat Dundar

Journal article  |  2022  |  SCIENTIFIC REPORTS

Axonal characterizations of connectomes in healthy and disease phenotypes are surprisingly incomplete and biased because unmyelina..

Computational modelling of nerve stimulation and recording with peripheral visceral neural interfaces

Calvin D Eiber, Sophie C Payne, Natalia P Biscola, Leif A Havton, Janet R Keast, Peregrine B Osborne, James B Fallon

Journal article  |  2021  |  JOURNAL OF NEURAL ENGINEERING

Objective.Neuromodulation of visceral nerves is being intensively studied for treating a wide range of conditions, but effective t..

Regional Targeting of Bladder and Urethra Afferents in the Lumbosacral Spinal Cord of Male and Female Rats: A Multiscale Analysis

JP Fuller-Jackson, PB Osborne, JR Keast

Journal article  |  2021  |  ENEURO

Sensorimotor circuits of the lumbosacral spinal cord are required for lower urinary tract (LUT) regulation as well as being engage..

Computational Modeling of an Endovascular Peripheral Nerve Interface.

JingYang Liu, David B Grayden, Janet R Keast, Sam E John

Conference Proceedings  |  2021  |  Annu Int Conf IEEE Eng Med Biol Soc

Implantable neuromodulation devices that interface with the peripheral nervous system are a promising approach to restore function..

Advancing our understanding of the neural control of the female human urethra

Claire C Yang, James A Hokanson, Janet R Keast

Journal article  |  2021  |  NEUROUROLOGY AND URODYNAMICS

Comparing endometriotic lesions with eutopic endometrium: time to shift focus?

Eliza M Colgrave, Janet R Keast, Sophie Bittinger, Martin Healey, Peter AW Rogers, Sarah J Holdsworth-Carson, Jane E Girling

Journal article  |  2021  |  HUMAN REPRODUCTION

Endometriosis is a heterogeneous disease in terms of patient symptoms, treatment responsiveness and the presentation of endometrio..

A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood

Anne E Turco, Steven R Oakes, Kimberly P Keil Stietz, Cheryl L Dunham, Diya B Joseph, Thrishna S Chathurvedula, Nicholas M Girardi, Andrew J Schneider, Joseph Gawdzik, Celeste M Sheftel, Peiqing Wang, Zunyi Wang, Dale E Bjorling, William A Ricke, Weiping Tang, Laura L Hernandez, Janet R Keast, Adrian D Bonev, Matthew D Grimes, Douglas W Strand, et al.

Journal article  |  2021  |  DISEASE MODELS & MECHANISMS

Benign Prostatic Hyperplasia / Lower Urinary Tract Dysfunction (BPH/LUTD) is a classic disease of aging which affects nearly all m..

A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood.

Anne E Turco, Steven R Oakes, Kimberly P Keil Stietz, Cheryl L Dunham, Diya B Joseph, Thrishna S Chathurvedula, Nicholas M Girardi, Andrew J Schneider, Joseph Gawdzik, Celeste M Sheftel, Peiqing Wang, Zunyi Wang, Dale E Bjorling, William A Ricke, Weiping Tang, Laura L Hernandez, Janet R Keast, Adrian D Bonev, Matthew D Grimes, Douglas W Strand, et al.

Journal article  |  2021  |  Dis Model Mech

Benign prostatic hyperplasia/lower urinary tract dysfunction (LUTD) affects nearly all men. Symptoms typically present in the fift..