Margaret Morris

Minocycline for the treatment of mental health and neurological conditions: study protocol of a systematic review and meta-analysis

Chiara C Bortolasci, Wolfgang Marx, Adam J Walker, Kyoko Hasebe, Bianca E Kavanagh, Margaret J Morris, Mohammadreza Mohebbi, Alyna Turner, Laura Gray, Lesley Berk, Ken Walder, Michael Berk, Olivia M Dean

Journal article  |  2020  |  BMJ OPEN

INTRODUCTION: Due to the anti-inflammatory, antioxidant and anti-apoptotic properties of minocycline, clinical trials have evaluat..

Neuropeptide Y affects thalamic reticular nucleus neuronal firing and network synchronization associated with suppression of spike-wave discharges

Idrish Ali, Arun Gandrathi, Thomas Zheng, Margaret J Morris, Terence J O'Brien, Chris French

Journal article  |  2018  |  EPILEPSIA

OBJECTIVES: Neuropeptide Y (NPY) potently suppresses spike-wave discharges (SWDs) in a genetic rat model of absence epilepsy (GAER..

Gene therapy mediated seizure suppression in Genetic Generalised Epilepsy: Neuropeptide Y overexpression in a rat model

Kim L Powell, Xavier Fitzgerald, Claire Shallue, Valentina Jovanovska, Matthias Klugmann, Georg von Jonquieres, Terence J O'Brien, Margaret J Morris

Journal article  |  2018  |  NEUROBIOLOGY OF DISEASE

Neuropeptide Y (NPY) is an important 36 amino acid peptide that is abundantly expressed in the mammalian CNS and is known to be an..

More Flavor for Flavonoid-Based Interventions?

Nadeem O Kaakoush, Margaret J Morris

Journal article  |  2017  |  Trends Mol Med

Poor diets are associated with obesity and a decline in cognitive function. Flavonoids are plant compounds that have been associat..

Effects of paternal obesity on growth and adiposity of male rat offspring.

Virginie Lecomte, Christopher A Maloney, Kristy W Wang, Margaret J Morris

Journal article  |  2017  |  Am J Physiol Endocrinol Metab

Emerging evidence suggests that paternal obesity plays an important role in offspring health. Our previous work using a rodent mod..

Editorial: Impact of Diet on Learning, Memory and Cognition.

Amy C Reichelt, R Fred Westbrook, Margaret J Morris

Journal article  |  2017  |  Front Behav Neurosci

Glucagon phosphorylates serine 552 of beta-catenin leading to increased expression of cyclin D1 and c-Myc in the isolated rat liver

Md Kamrul H Chowdhury, Magda K Montgomery, Margaret J Morris, Emmanuelle Cognard, Peter R Shepherd, Greg C Smith

Journal article  |  2015  |  ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

In the last 20 years the prevalence of metabolic disorders, in particular type 2 diabetes (T2D), has more than doubled. Recently, ..

Effects of long-term cycling between palatable cafeteria diet and regular chow on intake, eating patterns, and response to saccharin and sucrose

Sarah I Martire, R Fred Westbrook, Margaret J Morris

Journal article  |  2015  |  PHYSIOLOGY & BEHAVIOR

When exposed to a diet containing foods that are rich in fat and sugar, rats eat to excess and gain weight. We examined the effect..

Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

Lennart Zabeau, Cathy J Jensen, Sylvie Seeuws, Koen Venken, Annick Verhee, Dominiek Catteeuw, Geert van Loo, Hui Chen, Ken Walder, Jacob Hollis, Simon Foote, Margaret J Morris, Jose Van der Heyden, Frank Peelman, Brian J Oldfield, Justin P Rubio, Dirk Elewaut, Jan Tavernier

Journal article  |  2015  |  CELLULAR AND MOLECULAR LIFE SCIENCES

The adipocyte-derived cytokine leptin acts as a metabolic switch, connecting the body's metabolism to high-energy consuming proces..

Undernutrition during suckling in rats elevates plasma adiponectin and its receptor in skeletal muscle regardless of diet composition: a protective effect?

LJ Prior, E Velkoska, R Watts, D Cameron-Smith, MJ Morris

Journal article  |  2008  |  INTERNATIONAL JOURNAL OF OBESITY

OBJECTIVE: Nutrition during critical periods in early life may increase the subsequent risk of obesity, hypertension and metabolic..