Kevin Nicholas

Comparative analysis of milk microRNA in the therian lineage highlights the evolution of lactation

Christophe Lefevre, Pooja Venkat, Amit Kumar, Vengamanaidu Modepalli, Kevin R Nicholas

Journal article  |  2019  |  Reproduction, Fertility and Development

Guiding Development of the Neonate: Lessons from Mammalia

Kevin R Nicholas, Vengama Modepalli, Ashalyn P Watt, Lyn A Hinds, Amit Kumar, Christophe Lefevre, Julie A Sharp

Book Chapter  |  2019  |  Nestle Nutrition Institute workshop series

Significantly preterm and low-birthweight (LBW) babies have diminished lung and gut development, generally fail to thrive, have in..

Gene expression profiling of postnatal lung development in the marsupial gray short-tailed opossum (Monodelphis domestica) highlights conserved developmental pathways and specific characteristics during lung organogenesis

Vengamanaidu Modepalli, Amit Kumar, Julie A Sharp, Norman R Saunders, Kevin R Nicholas, Christophe Lefevre

Journal article  |  2018  |  BMC Genomics

Transcriptome analysis of mammary epithelial cell gene expression reveals novel roles of the extracellular matrix.

Stephen S Wanyonyi, Amit Kumar, Ryan Du Preez, Christophe Lefevre, Kevin R Nicholas

Journal article  |  2017  |  Biochemistry and Biophysics Reports

BACKGROUND: The unique lactation strategy of the tammar wallaby (Macropus eugeni) has been invaluable in evaluating the role of la..

Dimeric but not monomeric alpha-lactalbumin potentiates apoptosis by up regulation of ATF3 and reduction of histone deacetylase activity in primary and immortalised cells

Julie A Sharp, Amelia J Brennan, Galina Polekhina, David B Ascher, Christophe Lefevre, Kevin R Nicholas

Journal article  |  2017  |  Cellular Signalling

The tammar wallaby: A marsupial model to examine the timed delivery and role of bioactives in milk

Julie A Sharp, Stephen Wanyonyi, Vengama Modepalli, Ashalyn Watt, Sanjana Kuruppath, Lyn A Hinds, Amit Kumar, Helen E Abud, Christophe Lefevre, Kevin R Nicholas

Journal article  |  2017  |  General and Comparative Endocrinology

Molecular evolution of a novel marsupial S100 protein (S100A19) which is expressed at specific stages of mammary gland and gut development

Joly HL Kwek, Alicia Wynne, Christophe Lefevre, Mary Familari, Kevin R Nicholas, Julie A Sharp

Journal article  |  2013  |  Molecular Phylogenetics and Evolution

The mammary gland-specific marsupial ELP and eutherian CTI share a common ancestral gene

Elizabeth A Pharo, Alison A De Leo, Marilyn B Renfree, Peter C Thomson, Christophe M Lefevre, Kevin R Nicholas

Journal article  |  2012  |  BMC Evolutionary Biology

The mammary gland-specific marsupial ELP and eutherian CTI share a common ancestral gene.

Elizabeth A Pharo, Alison A De Leo, Marilyn B Renfree, Peter C Thomson, Christophe M Lefèvre, Kevin R Nicholas

Journal article  |  2012  |  BMC Evolutionary Biology

BACKGROUND: The marsupial early lactation protein (ELP) gene is expressed in the mammary gland and the protein is secreted into mi..

Acute involution in the tammar wallaby: Identification of genes and putative novel milk proteins implicated in mammary gland function

Elie Khalil, Matthew Robert Digby, Peter Campbell Thomson, Christophe Lefevre, Sonia Louise Mailer, Cate Pooley, Kevin Roy Nicholas

Journal article  |  2011  |  Genomics

Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development

Marilyn B Renfree, Anthony T Papenfuss, Janine E Deakin, James Lindsay, Thomas Heider, Katherine Belov, Willem Rens, Paul D Waters, Elizabeth A Pharo, Geoff Shaw, Emily Swwong, Christophe M Lefevre, Kevin R Nicholas, Yoko Kuroki, Matthew J Wakefield, Kyall R Zenger, Chenwei Wang, Malcolm Ferguson-Smith, Frank W Nicholas, Danielle Hickford, et al.

Journal article  |  2011  |  GENOME BIOLOGY

Blood plasma concentrations of metabolic hormones and glucose during extended lactation in grazing cows or cows fed a total mixed ration

KK Delany, KL Macmillan, C Grainger, PC Thomson, D Blache, KR Nicholas, MJ Auldist

Journal article  |  2010  |  Journal of Dairy Science

Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants

Karensa K Menzies, Heather J Lee, Christophe Lefevre, Christopher J Ormandy, Keith L Macmillan, Kevin R Nicholas

Journal article  |  2010  |  Functional & Integrative Genomics

Molecular Insights Into Evolution of the Vertebrate Gut: Focus on Stomach and Parietal Cells in the Marsupial, Macropus eugenii

Joly Kwek, Robbert De Iongh, Kevin Nicholas, Mary Familari

Journal article  |  2009  |  Journal of Experimental Zoology. Part B: Molecular and Developmental Evolution

Characterization of the tammar wallaby (Macropus eugenii) whey acidic protein gene; new insights into the function of the protein

Denijal Topcic, Aurelie Auguste, Alison A De Leo, Christophe Lefevre, Matthew R Digby, Kevin R Nicholas

Journal article  |  2009  |  Evolution & Development

Molecular analysis of tammar (Macropus eugenii) mammary epithelial cells stimulated with lipopolysaccharide and lipoteichoic acid

Kerry A Daly, Sonia L Mailer, Matthew R Digby, Christophe Lefevre, Peter Thomson, Elizabeth Deane, Kevin R Nicholas, Peter Williamson

Journal article  |  2009  |  Veterinary Immunology and Immunopathology

Insulin regulates milk protein synthesis at multiple levels in the bovine mammary gland

Karensa K Menzies, Christophe Lefevre, Keith L Macmillan, Kevin R Nicholas

Journal article  |  2009  |  Functional & Integrative Genomics

Cross-fostering of the tammar wallaby (Macropus eugenii) pouch young accelerates fore-stomach maturation

Joly HL Kwek, Robbert De Iongh, Matthew R Digby, Marilyn B Renfree, Kevin R Nicholas, Mary Familari

Journal article  |  2009  |  Mechanisms of Development

Characterisation of monotreme caseins reveals lineage-specific expansion of an ancestral casein locus in mammals

Christophe M Lefevre, Julie A Sharp, Kevin R Nicholas

Journal article  |  2009  |  Reproduction, Fertility and Development

The comparative genomics of tammar wallaby and Cape fur seal lactation models to examine function of milk proteins

Julie A Sharp, Matthew Digby, Christophe Lefevre, Sonia Mailer, Elie Khalil, Denijal Topcic, Aurelie Auguste, Joly Kwek, Amelia J Brennan, Mary Familari, Kevin R Nicholas

Book Chapter  |  2009

Significance, origin and function of bovine milk proteins: the biological implications of manipulation or modification

PA Sheehy, P Williamson, J SHARP, K Menzies, C LEFEVRE, M DIGBY, K NICHOLAS, PC Wynn

Book Chapter  |  2009

Normal mammary gland growth and lactation capacity in pregnant relaxin-deficient mice

Laura J Parry, Lenka A Vodstrcil, Anna Madden, Stephanie H Amir, Katrina Baldwin, Mary E Wlodek, Kevin R Nicholas

Journal article  |  2009  |  Reproduction, Fertility and Development

Changes in milk protein composition during acute involution at different phases of tammar wallaby (Macropus eugenii) lactation

Elie Khalil, Matthew R Digby, Paul O'Donnell, Kevin R Nicholas

Journal article  |  2008  |  Comparative Biochemistry and Physiology B - Biochemistry and Molecular Biology

Genome analysis of the platypus reveals unique signatures of evolution

Wesley C Warren, LaDeana W Hillier, Jennifer A Marshall Graves, Ewan Birney, Chris P Ponting, Frank Grutzner, Katherine Belov, Webb Miller, Laura Clarke, Asif T Chinwalla, Shiaw-Pyng Yang, Andreas Heger, Devin P Locke, Pat Miethke, Paul D Waters, Frederic Veyrunes, Lucinda Fulton, Bob Fulton, Tina Graves, John Wallis, et al.

Journal article  |  2008  |  Nature

Identification, characterization and expression of cathelicidin in the pouch young of tammar wallaby (Macropus eugenii)

Kerry A Daly, Matthew R Digby, Christophe Lefevre, Kevin R Nicholas, Elizabeth M Deane, Peter Williamson

Journal article  |  2008  |  Comparative Biochemistry and Physiology B - Biochemistry and Molecular Biology

A population of mammary epithelial cells do not require hormones or growth factors to survive

Amelia J Brennan, Julie A Sharp, Elie Khalil, Matthew R Digby, Sonia L Mailer, Christophe M Lefevre, Kevin R Nicholas

Journal article  |  2008  |  Journal of Endocrinology

Uteroplacental insufficiency alters the mammary gland response to lactogenic hormones in vitro

Rachael O'Dowd, Mary E Wlodek, Kevin R Nicholas

Journal article  |  2008  |  Reproduction, Fertility and Development

Filtering microarray correlations by statistical literature analysis yields potential hypotheses for lactation research

HTM LING, C LEFEVRE, K NICHOLAS

Journal article  |  2008  |  The Python Papers

Lactation transcriptomics in the Australian marsupial, Macropus eugenii: transcript sequencing and quantification

Christophe M Lefevre, Matthew R Digby, Jane C Whitley, Yvan Strahm, Kevin R Nicholas

Journal article  |  2007  |  BMC Genomics

Molecular evolution of monotreme and marsupial whey acidic protein genes

Julie A Sharp, Christophe Lefevre, Kevin R Nicholas

Journal article  |  2007  |  Evolution & Development

The fur seal - a model lactation phenotype to explore molecular factors involved in the initiation of apoptosis at involution

Julie A Sharp, Christophe Lefevre, Amelia J Brennan, Kevin R Nicholas

Journal article  |  2007  |  Journal of Mammary Gland Biology and Neoplasia

The tammar wallaby: A model to examine endocrine and local control of lactation

Amelia J Brennan, Julie A Sharp, Matthew R Digby, Kevin R Nicholas

Journal article  |  2007  |  IUBMB Life

The endocrine regulation of milk lipid synthesis and secretion in tammar wallaby (Macropus eugenii)

Joly HL Kwek, Chakra Wijesundera, Matthew R Digby, Kevin R Nicholas

Journal article  |  2007  |  Biochimica et Biophysica Acta - General Subjects

Reconstruction of protein-protein interaction pathways by mining subject-verb-objects intermediates

Maurice HT Ling, Christophe Lefevre, Kevin R Nicholas, Feng Lin

Book Chapter  |  2007  |  Lecture Notes in Artificial Intelligence

The expression of beta-1,3 galactosyltransferase and beta-1,4 galactosyltransferase enzymatic activities in the mammary gland of the tammar wallaby (Macropus eugenii) during early lactation

KK Menzies, KR Nicholas

Journal article  |  2007  |  Biochimica et Biophysica Acta - General Subjects

The tammar wallaby and fur seal: Models to examine local control of lactation

AJ Brennan, JA Sharp, C Lefevre, D Topcic, A Auguste, M Digby, KR Nicholas

Journal article  |  2007  |  Journal of Dairy Science

Comparative genomics and lactation: Making more money from milk

C Wynn, K NICHOLAS, L Riley, P Sheehy

Journal article  |  2007  |  Pakistan Congress of Zoology Proceedings

A quantitative study of the morphological development and bacterial colonisation of the gut of the tammar wallaby Macropus eugenii eugenii and brushtail possum Trichosurus vulpecula during in-pouch development

RG Lentle, D Dey, C Hulls, DJ Mellor, PJ Moughan, KJ Stafford, K Nicholas

Journal article  |  2006  |  Journal of Comparative Physiology B: Biochemical, Systemic and Environmental Physiology

Species-specific cell-matrix interactions are essential for differentiation of alveoli like structures and milk gene expression in primary mammary cells of the Cape fur seal (Arctocephalus pusillus pusillus)

Julie A Sharp, Kylie N Cane, Sonia L Mailer, W Herman Oosthuizen, John PY Arnould, Kevin R Nicholas

Journal article  |  2006  |  Matrix Biology

Fur seal adaptations to lactation: Insights into mammary gland function

JA Sharp, KN Cane, C Lefevre, JPY Arnould, KR Nicholas

Journal article  |  2006  |  Current Topics in Developmental Biology

The tammar wallaby: A model to examine endocrine and local control of lactation

AJ BRENNAN, J SHARP, M DIGBY, K NICHOLAS

Journal article  |  2006  |  Australian Biochemist

Characterization of two whey protein genes in the Australian dasyurid marsupial, the stripe-faced dunnart (Sminthopsis macroura)

AA De Leo, C Lefevre, D Topcic, E Pharo, JF Cheng, P Frappell, M Westerman, JAM Graves, KR Nicholas

Journal article  |  2006  |  CYTOGENETIC AND GENOME RESEARCH

Cross-fostering in Macropus eugenii leads to increased weight but not accelerated gastrointestinal maturation

R Waite, A Giraud, J Old, M Howlett, G Shaw, K Nicholas, M Familari

Journal article  |  2005  |  Journal of Experimental Zoology

Characterisation of proteins in the milk of fur seals

KN Cane, JPY Arnould, KR Nicholas

Journal article  |  2005  |  Comparative Biochemistry and Physiology B - Biochemistry and Molecular Biology

Positive and negative regulatory elements in the late lactation protein-A gene promoter from the tammar wallaby (Macropus eugenii)

JF Trott, TE Adams, M Wilson, KR Nicholas

Journal article  |  2005  |  Biochimica et Biophysica Acta-Gene Structure & Expression

The lactation cycle of the fur seal

JA Sharp, K Cane, JP Arnould, KR Nicholas

Journal article  |  2005  |  Journal of Dairy Research

Sequencing and mapping hemoglobin gene clusters in the Australian model dasyurid marsupial Sminthopsis macroura

AA De Leo, D Wheeler, C Lefevre, JF Cheng, R Hope, J Kuliwaba, KR Nicholas, M Westerman, JAM Graves

Journal article  |  2005  |  Cytogenetic and Genome Research

Hormone-dependent milk protein gene expression in bovine mammary explants from biopsies at different stages of pregnancy

PA Sheehy, JJ Della-Vedova, KR Nicholas, PC Wynn

Journal article  |  2004  |  Journal of Dairy Research

Commercial aspects of cloning and genetic modification in cattle

IM Lewis, AJ French, RT Tecirlioglu, G Vajta, AE McClintock, KR Nicholas, KA Zuelke, MK Holland, AO Trounson

Journal article  |  2004  |  Australian Journal of Experimental Agriculture

Maternal regulation of milk composition, milk production, and pouch young development during lactation in the tammar wallaby (Macropus eugenii)

JF Trott, KJ Simpson, RLC Moyle, CM Hearn, G Shaw, KR Nicholas, MB Renfree

Journal article  |  2003  |  Biology of Reproduction

The comparative biology of whey proteins

KJ Simpson, KR Nicholas

Journal article  |  2002  |  Journal of Mammary Gland Biology and Neoplasia

Expression of novel lipocalin-like milk protein gene is developmentally-regulated during lactation in the tammar wallaby, Macropus eugenii

JF Trott, MJ Wilson, RC Hovey, DC Shaw, KR Nicholas

Journal article  |  2002  |  Gene

Differential expression of the whey acidic protein gene during lactation in the brushtail possum (Trichosurus vulpecula)

J Demmer, SJ Stasiuk, MR Grigor, KJ Simpson, KR Nicholas

Journal article  |  2001  |  Biochimica et Biophysica Acta-Gene Structure & Expression

Secretion of whey acidic protein and cystatin is down regulated at mid-lactation in the red kangaroo (Macropus rufus)

KR Nicholas, JA Fisher, E Muths, J Trott, PA Janssens, C Reich, DC Shaw

Journal article  |  2001  |  Comparative Biochemistry and Physiology A - Molecular and Integrative Physiology