Julie Healer

A comparison of non-magnetic and magnetic beads for measuring IgG antibodies against Plasmodium vivax antigens in a multiplexed bead-based assay using Luminex technology (Bio-Plex 200 or MAGPIX)

Ramin Mazhari, Jessica Brewster, Rich Fong, Caitlin Bourke, Zoe SJ Liu, Eizo Takashima, Takafumi Tsuboi, Wai-Hong Tham, Matthias Harbers, Chetan Chitnis, Julie Healer, Maria Ome-Kaius, Jetsumon Sattabongkot, James Kazura, Leanne J Robinson, Christopher King, Ivo Mueller, Rhea J Longley

Journal article  |  2020  |  PLOS ONE

Multiplexed bead-based assays that use Luminex® xMAP® technology have become popular for measuring antibodies against proteins of ..

Development and application of a high-throughput screening assay for identification of small molecule inhibitors of the P. falciparum reticulocyte binding-like homologue 5 protein

Brad E Sleebs, Kate E Jarman, Sonja Frolich, Wilson Wong, Julie Healer, Weiwen Dai, Isabelle S Lucet, Danny W Wilson, Alan F Cowman

Journal article  |  2020  |  International Journal for Parasitology: Drugs and Drug Resistance

The P. falciparum parasite, responsible for the disease in humans known as malaria, must invade erythrocytes to provide an environ..

Trends Talk MAM 2020: Growing Strong on the 20th Anniversary

Alexis Kaushansky, Carol Sibley, Geoff McFadden, Susan Charman, Denise Doolan, Michael Good, Erika Flannery, Julie Healer, Michael Duffy, Terrie Taylor, Alister Craig, Leann Tilley, Paul Gilson

Journal article  |  2020  |  Trends in Parasitology

Development and validation of serological markers for detecting recent Plasmodium vivax infection

Rhea J Longley, Michael T White, Eizo Takashima, Jessica Brewster, Masayuki Morita, Matthias Harbers, Thomas Obadia, Leanne J Robinson, Fumie Matsuura, Zoe SJ Liu, Connie SN Li-Wai-Suen, Wai-Hong Tham, Julie Healer, Christele Huon, Chetan E Chitnis, Wang Nguitragool, Wuelton Monteiro, Carla Proietti, Denise L Doolan, Andre M Siqueira, et al.

Journal article  |  2020  |  Nature Medicine

A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals carrying clinically silent and undete..

Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

Paola Favuzza, Manuel de Lera Ruiz, Jennifer K Thompson, Tony Triglia, Anna Ngo, Ryan WJ Steel, Marissa Vavrek, Janni Christensen, Julie Healer, Christopher Boyce, Zhuyan Guo, Mengwei Hu, Tanweer Khan, Nicholas Murgolo, Lianyun Zhao, Jocelyn Sietsma Penington, Kitsanapong Reaksudsan, Kate Jarman, Melanie H Dietrich, Lachlan Richardson, et al.

Journal article  |  2020  |  Cell Host & Microbe

Artemisin combination therapy (ACT) is the main treatment option for malaria, which is caused by the intracellular parasite Plasmo..

Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes

Julie Healer, Wilson Wong, Jennifer K Thompson, Wengqiang He, Richard W Birkinshaw, Kazutoyo Miura, Carol A Long, Vladislav Soroka, Teit Max Moscote Sogaard, Thomas Jorgensen, Willem A de Jongh, Christopher Weir, Ella Svahn, Peter E Czabotar, Wai-Hong Tham, Ivo Mueller, Paul N Barlow, Alan F Cowman

Journal article  |  2019  |  Cellular Microbiology

Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria

Wen-Qiang He, Ahmad Rushdi Shakri, Rukmini Bhardwaj, Camila T Franca, Danielle I Stanisic, Julie Healer, Benson Kiniboro, Leanne J Robinson, Micheline Guillotte-Blisnick, Christele Huon, Peter Siba, Alan Cowman, Christopher L King, Wai-Hong Tham, Chetan E Chitnis, Ivo Mueller

Journal article  |  2019  |  PLoS Neglected Tropical Diseases

Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex

Wilson Wong, Rick Huang, Sebastien Menant, Chuan Hong, Jarrod J Sandow, Richard W Birkinshaw, Julie Healer, Anthony N Hodder, Usheer Kanjee, Christopher J Tonkin, Denise Heckmann, Vladislav Soroka, Teit Max Moscote Sogaard, Thomas Jorgensen, Manoj T Duraisingh, Peter E Czabotar, Willem A de Jongh, Wai-Hong Tham, Andrew I Webb, Zhiheng Yu, et al.

Journal article  |  2019  |  Nature

A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial

Rebecca Pawliw, Rebecca Farrow, Silvana Sekuloski, Helen Jennings, Julie Healer, Phuong Thuan, Pri Sathe, Cielo Pasay, Krystal Evans, Alan F Cowman, Louis Schofield, Nanhua Chen, James McCarthy, Katharine Trenholme

Journal article  |  2018  |  Malaria Journal

Mechanisms of naturally acquired immunity to P-falciparum and approaches to identify merozoite antigen targets

Julie Healer, Chris Y Chiu, Diana S Hansen

Journal article  |  2018  |  Parasitology