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Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins pred..
A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum bl..
Mechanisms of naturally acquired immunity to P-falciparum and approaches to identify meroz..
Identification of highly-protective combinations of Plasmodium vivax recombinant proteins ..
Displaying the 34 most recent scholarly works by Julie Healer.
Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes
Julie Healer, Wilson Wong, Jennifer K Thompson, Wengqiang He, Richard W Birkinshaw, Kazutoyo Miura, Carol A Long, Vladislav Soroka, Teit Max Moscote Sogaard, Thomas Jorgensen, Willem A de Jongh, Christopher Weir, Ella Svahn, Peter E Czabotar, Wai-Hong Tham, Ivo Mueller, Paul N Barlow, Alan F Cowman
Journal article | 2019 | Cellular Microbiology
Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria
Wen-Qiang He, Ahmad Rushdi Shakri, Rukmini Bhardwaj, Camila T Franca, Danielle I Stanisic, Julie Healer, Benson Kiniboro, Leanne J Robinson, Micheline Guillotte-Blisnick, Christele Huon, Peter Siba, Alan Cowman, Christopher L King, Wai-Hong Tham, Chetan E Chitnis, Ivo Mueller
Journal article | 2019 | PLOS Neglected Tropical Diseases
Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex
Wilson Wong, Rick Huang, Sebastien Menant, Chuan Hong, Jarrod J Sandow, Richard W Birkinshaw, Julie Healer, Anthony N Hodder, Usheer Kanjee, Christopher J Tonkin, Denise Heckmann, Vladislav Soroka, Teit Max Moscote Sogaard, Thomas Jorgensen, Manoj T Duraisingh, Peter E Czabotar, Willem A de Jongh, Wai-Hong Tham, Andrew I Webb, Zhiheng Yu, et al.
Journal article | 2019 | Nature
A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial
Rebecca Pawliw, Rebecca Farrow, Silvana Sekuloski, Helen Jennings, Julie Healer, Phuong Thuan, Pri Sathe, Cielo Pasay, Krystal Evans, Alan F Cowman, Louis Schofield, Nanhua Chen, James McCarthy, Katharine Trenholme
Journal article | 2018 | Malaria Journal
Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development
Camila Tenorio Franca, Michael T White, Wen-Qiang He, Jessica B Hostetler, Jessica Brewster, Gabriel Frato, Indu Malhotra, Jakub Gruszczyk, Christele Huon, Enmoore Lin, Benson Kiniboro, Anjali Yadava, Peter Siba, Mary R Galinski, Julie Healer, Chetan Chitnis, Alan F Cowman, Eizo Takashima, Takafumi Tsuboi, Wai-Hong Tham, et al.
Journal article | 2017 | eLife
Different Regions of Plasmodium falciparum Erythrocyte-Binding Antigen 175 Induce Antibody Responses to Infection of Varied Efficacy
Chris Y Chiu, Michael T White, Julie Healer, Jenny K Thompson, Peter M Siba, Ivo Mueller, Alan F Cowman, Diana S Hansen
Journal article | 2016 | Journal of Infectious Diseases
A Next-generation Genetically Attenuated Plasmodium falciparum Parasite Created by Triple Gene Deletion
Sebastian A Mikolajczak, Viswanathan Lakshmanan, Matthew Fishbaugher, Nelly Camargo, Anke Harupa, Alexis Kaushansky, Alyse N Douglass, Michael Baldwin, Julie Healer, Matthew O'Neill, Phuong Thuan, Alan Cowman, Stefan HI Kappe
Journal article | 2014 | Molecular Therapy
Association of antibodies to Plasmodium falciparum reticulocyte binding protein homolog 5 with protection from clinical malaria
Chris YH Chiu, Julie Healer, Jennifer K Thompson, Lin Chen, Aiki Kaul, Laxman Savergave, Arjun Raghuwanshi, Connie SN Li Wai Suen, Peter M Siba, Louis Schofield, Ivo Mueller, Alan F Cowman, Diana S Hansen
Journal article | 2014 | Frontiers in Microbiology
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers
Michele Spring, Jittawadee Murphy, Robin Nielse, Megan Dowler, Jason W Bennett, Stasya Zarling, Jack Williams, Patricia de la Vega, Lisa Ware, Jack Komisar, Mark Polhemus, Thomas L Richie, Judy Epstein, Cindy Tamminga, Ilin Chuang, Nancy Richie, Michael O'Neil, D Gray Heppner, Julie Healer, Matthew O'Neill, et al.
Journal article | 2013 | Vaccine
Vaccination with Conserved Regions of Erythrocyte-Binding Antigens Induces Neutralizing Antibodies against Multiple Strains of Plasmodium falciparum
Julie Healer, Jennifer K Thompson, David T Riglar, Danny W Wilson, Yu-H C Chiu, Kazutoyo Miura, Lin Chen, Anthony N Hodder, Carole A Long, Diana S Hansen, Jake Baum, Alan F Cowman
Journal article | 2013 | PLoS One
Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development
Jack S Richards, Thangavelu U Arumugam, Linda Reiling, Julie Healer, Anthony N Hodder, Freya JI Fowkes, Nadia Cross, Christine Langer, Satoru Takeo, Alex D Uboldi, Jennifer K Thompson, Paul R Gilson, Ross L Coppel, Peter M Siba, Christopher L King, Motomi Torii, Chetan E Chitnis, David L Narum, Ivo Mueller, Brendan S Crabb, et al.
Journal article | 2013 | Journal of Immunology
Insights into Duffy Binding-like Domains through the Crystal Structure and Function of the Merozoite Surface Protein MSPDBL2 from Plasmodium falciparum
Anthony N Hodder, Peter E Czabotar, Alessandro D Uboldi, Oliver B Clarke, Clara S Lin, Julie Healer, Brian J Smith, Alan F Cowman
Journal article | 2012 | Journal of Biological Chemistry
Discovery of GAMA, a Plasmodium falciparum Merozoite Micronemal Protein, as a Novel Blood-Stage Vaccine Candidate Antigen
Thangavelu U Arumugam, Satoru Takeo, Tsutomu Yamasaki, Amporn Thonkukiatkul, Kazutoyo Miura, Hitoshi Otsuki, Hong Zhou, Carole A Long, Jetsumon Sattabongkot, Jennifer Thompson, Danny W Wilson, James G Beeson, Julie Healer, Brendan S Crabb, Alan F Cowman, Motomi Torii, Takafumi Tsuboi
Journal article | 2011 | Infect. Immun.
The role of osmiophilic bodies and Pfg377 expression in female gametocyte emergence and mosquito infectivity in the human malaria parasite Plasmodium falciparum
Tania F de Koning-Ward, Anna Olivieri, Lucia Bertuccini, Andrew Hood, Francesco Silvestrini, Konstantinos Charvalias, Pedro Berzosa Diaz, Grazia Camarda, Terry F McElwain, Tony Papenfuss, Julie Healer, Lucilla Baldassarri, Brendan S Crabb, Pietro Alano, Lisa C Ranford-Cartwright
Journal article | 2008 | Molecular Microbiology
Alterations in local chromatin environment are involved in silencing and activation of subtelomeric var genes in Plasmodium falciparum
Till S Voss, Christopher J Tonkin, Allison J Marty, Jennifer K Thompson, Julie Healer, Brendan S Crabb, Alan F Cowman
Journal article | 2007 | Molecular Microbiology
A conserved region in the EBL proteins is implicated in microneme targeting of the malaria parasite Plasmodium falciparum
Moritz Treeck, Nicole S Struck, Silvia Haase, Christine Langer, Susann Herrmann, Julie Healer, Alan F Cowman, Tim W Gilberger
Journal article | 2006 | Journal of Biological Chemistry
Transcribed var genes associated with placental malaria in Malawian women
Michael F Duffy, Aphrodite Caragounis, Rintis Noviyanti, Helen M Kyriacou, Ee Ken Choong, Katja Boysen, Julie Healer, J Alexandra Rowe, Malcolm E Molyneux, Graham V Brown, Stephen J Rogerson
Journal article | 2006 | Infection and Immunity
Transmission-blocking immunity to Plasmodium falciparum in malaria-immune individuals is associated with antibodies to the gamete surface protein Pfs230.
J Healer, D McGuinness, R Carter, E Riley
Journal article | 1999 | Parasitology
Malaria-immune human sera were tested for their ability to affect the infectivity of Plasmodium falciparum gametocytes to Anophele..
Phagocytosis does not play a major role in naturally acquired transmission-blocking immunity to Plasmodium falciparum malaria.
J Healer, A Graszynski, E Riley
Journal article | 1999 | Infection and Immunity
Phagocytosis of Plasmodium falciparum sexual stages in vitro and within the mosquito midgut was assayed in order to assess its rol..
Complement-mediated lysis of Plasmodium falciparum gametes by malaria-immune human sera is associated with antibodies to the gamete surface antigen Pfs230.
J Healer, D McGuinness, P Hopcroft, S Haley, R Carter, E Riley
Journal article | 1997 | Infection and Immunity
Antibodies to the sexual-stage surface antigens of Plasmodium falciparum, Pfs230 and Pfs48/45, can abolish the infectivity of game..
Medical Biology (W.E.H.I.)
Doctor of Philosophy
The University of Edinburgh
Master of Philosophy
Imperial College of Science Technology and Medicine
Bachelor of Science (honours)
The University of Glasgow