David O'Neal

COVID-19, Type 1 Diabetes Clinical Practice, Research, and Remote Medical Care: A View From the Land Down-Under.

Nisha Venkatesh, Barbora Paldus, Melissa H Lee, Richard J MacIsaac, Alicia J Jenkins, David N O'Neal

Journal article  |  2020  |  Journal of Diabetes Science and Technology

A safety and pharmacodynamics study of temelimab, an antipathogenic human endogenous retrovirus type W envelope monoclonal antibody, in patients with type 1 diabetes

Francois Curtin, Bernard Champion, Peter Davoren, Sally Duke, Elif Ekinci, Chris Gilfillan, Claire Morbey, Thomas Nathow, Trisha O'Moore-Sullivan, David O'Neal, Adam Roberts, Stephen Stranks, Bronwyn Stuckey, Parind Vora, Sam Malpass, David Lloyd, Nicole Maestracci-Beard, Benedicte Buffet, Gabrielle Kornmann, Corinne Bernard, et al.

Journal article  |  2020  |  Diabetes, Obesity and Metabolism

AIM: To report the first study of temelimab, a monoclonal antibody neutralizing the pathogenic human endogenous retrovirus type W ..

TITLE: CONTINUOUS GLUCOSE MONITORING VERSUS SELF-MONITORING OF BLOOD GLUCOSE TO ASSESS GLYCEMIA IN GESTATIONAL DIABETES.

Dessi Zaharieva, Jessie H Teng, May Lea Ong, Melissa H Lee, Barbora Paldus, Linda Jackson, Christine A Holihan, Alexis Shub, Sheetal Tipnis, Ohad Cohen, David Norman O'Neal, Balasubramanian Krishnamurthy

Journal article  |  2020  |  Diabetes Technology & Therapeutics

BACKGROUND: Gestational diabetes mellitus (GDM) management using self-monitoring blood glucose (SMBG) does not normalise pregnancy..

Adults With Diabetes Distress Often Want to Talk With Their Health Professionals About It: Findings From an Audit of 4 Australian Specialist Diabetes Clinics.

Christel Hendrieckx, Jennifer A Halliday, Sienna Russell-Green, Neale Cohen, Peter G Colman, Alicia Jenkins, David O'Neal, Jane Speight

Journal article  |  2020  |  Canadian Journal of Diabetes

OBJECTIVES: In an unselected clinical sample, we aimed to: 1) investigate the willingness of adults with diabetes to talk with the..

Glucose and Counterregulatory Responses to Exercise in Adults With Type 1 Diabetes and Impaired Awareness of Hypoglycemia Using Closed-Loop Insulin Delivery: A Randomized Crossover Study

Melissa H Lee, Sara Vogrin, Barbora Paldus, Dilshani Jayawardene, Hannah M Jones, Sybil A McAuley, Varuni Obeyesekere, Judith Gooley, Andre La Gerche, Richard J MacIsaac, Vijaya Sundararajan, Alicia J Jenkins, Glenn M Ward, David N O'Neal

Journal article  |  2020  |  Diabetes Care

OBJECTIVE: To evaluate exercise-related glucose and counterregulatory responses (CRR) in adults with type 1 diabetes with impaired..

ASSESSMENT OF GLYCAEMIA BY FINGERSTICK BLOOD GLUCOSE MONITORING MAY UNDERESTIMATE THE REQUIREMENT FOR INSULIN TO ADDRESS ELEVATED NOCTURNAL GLUCOSE LEVELS IN WOMEN WITH GDM

D Zaharieva, B Krishnamurthy, J Teng, M Ong, M Lee, B Paldus, C Houlihan, A Shub, O Cohen, D O'Neal

Conference Proceedings  |  2020  |  DIABETES TECHNOLOGY & THERAPEUTICS

Use of professional-mode flash glucose monitoring, at 3-month intervals, in adults with type 2 diabetes in general practice (GP-OSMOTIC): a pragmatic, open-labe 12-month, randomised controlled trial

John Furler, David O'Neal, Jane Speight, Irene Blackberry, Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Katie de La Rue, Louise Ginnivan, Rebecca Doyle, Elizabeth Holmes-Truscott, Kamlesh Khunti, Kim Dalziel, Jason Chiang, Ralph Audehm, Mark Kennedy, Malcolm Clark, Alicia Jenkins, Amelia J Lake, Andrzej S Januszewski, Max Catchpool, et al.

Journal article  |  2020  |  The Lancet Diabetes & Endocrinology

BACKGROUND: Continuous glucose monitoring, either real-time (personal) or retrospective (professional mode), can identify day-to-d..

HbA1c variability in adults with type 1 diabetes on continuous subcutaneous insulin infusion (CSII) therapy compared to multiple daily injection (MDI) treatment.

Emma S Scott, Rachel T McGrath, Andrzej S Januszewski, Daniel Calandro, Anandwardhan A Hardikar, David N O'Neal, Gregory Fulcher, Alicia J Jenkins

Journal article  |  2019  |  BMJ Open

OBJECTIVE: To determine if continuous subcutaneous insulin infusion (CSII) therapy is associated with lower glycated haemoglobin (..

Health-related behaviours in a remote Indigenous population with Type 2 diabetes: a Central Australian primary care survey in the Telehealth Eye and Associated Medical Services Network [TEAMSnet] project

D Xu, A Jenkins, C Ryan, A Keech, A Brown, J Boffa, K O'Dea, SE Bursell, L Brazionis, David O'Neal, Danny Liew, Tien Wong, Hugh Taylor, Anthony Keech, Ecosse Lamoureux, Mark Horton, Laima Brazionis, Christopher Ryan, Justin Tse

Journal article  |  2019  |  Diabetic Medicine

Psychological impact of 3-monthly retrospective continuous glucose monitoring (rCGM) in adults with type 2 diabetes in primary care: secondary results of the GP-OSMOTIC RCT

J Speight, E Holmes-Truscott, S Thuraisingam, J Manski-Nankervis, K de La Rue, L Ginnivan, D O'Neal, J Furler

Conference Proceedings  |  2019  |  DIABETOLOGIA

The Clinical Case for the Integration of a Ketone Sensor as Part of a Closed Loop Insulin Pump System.

Melissa H Lee, Barbora Paldus, Balasubramanium Krishnamurthy, Sybil A McAuley, Rajiv Shah, Alicia J Jenkins, David N O'Neal

Journal article  |  2019  |  Journal of Diabetes Science and Technology

Closed loop (CL) systems deliver insulin with a rapid onset and offset in action. Although favorable overall, the absence of a lon..

SGLT2 Inhibitors Increase the Risk of Diabetic Ketoacidosis Developing in the Community and During Hospital Admission

Peter S Hamblin, Rosemary Wong, Elif Ekinci, Spiros Fourlanos, Sonali Shah, Alicia R Jones, Matthew JL Hare, Genevieve L Calder, Dilan Seneviratne Epa, Elizabeth M George, Rinky Giri, Mark A Kotowicz, Mervyn Kyi, Nicole Lafontaine, Richard J MacIsaac, Brendan J Nolan, David N O'Neal, Debra Renouf, Suresh Varadarajan, Jennifer Wong, et al.

Journal article  |  2019  |  The Journal of Clinical Endocrinology & Metabolism

CONTEXT: Diabetic ketoacidosis (DKA) has been associated with the use of sodium glucose cotransporter 2 inhibitors (SGLT2is). OBJE..

Glucose Control in Adults with Type 1 Diabetes Using a Medtronic Prototype Enhanced-Hybrid Closed-Loop System: A Feasibility Study

Melissa H Lee, Sara Vogrin, Barbora Paldus, Hannah M Jones, Varuni Obeyesekere, Catriona Sims, Sue-Anne Wyatt, Glenn M Ward, Sybil A McAuley, Richard J MacIsaac, Balasubramanian Krishnamurthy, Vijaya Sundararajan, Alicia J Jenkins, David N O'Neal

Journal article  |  2019  |  Diabetes Technology & Therapeutics

Hypoglycemia in People with Type 2 Diabetes and CKD

Iram Ahmad, Leila R Zelnick, Zona Batacchi, Nicole Robinson, Ashveena Dighe, Jo-Anne E Manski-Nankervis, John Furler, David N O'Neal, Randie Little, Dace Trence, Irl B Hirsch, Nisha Bansal, Ian H de Boer

Journal article  |  2019  |  Clinical Journal of the American Society of Nephrology

BACKGROUND AND OBJECTIVES: Among people with diabetes mellitus, CKD may promote hypoglycemia through altered clearance of glucose-..

The early detection of atherosclerosis in type 1 diabetes: why, how and what to do about it.

Alicia Jenkins, Andrzej Januszewski, David O'Neal

Journal article  |  2019  |  Cardiovascular Endocrinology & Metabolism

The major cause of morbidity and often premature mortality in people with type I diabetes (T1D) is cardiovascular disease owing to..

Prescribing of diabetes medications to people with type 2 diabetes and chronic kidney disease: a national cross-sectional study

Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Janet K Sluggett, Gary Kilov, John Furler, David O'Neal, Alicia Jenkins

Journal article  |  2019  |  BMC FAMILY PRACTICE

GLUCOSE CONTROL IN ADULTS WITH TYPE 1 DIABETES USING A MEDTRONIC ENHANCED-HYBRID CLOSED-LOOP SYSTEM (E-HCL)

M Lee, B Paldus, H Jones, S Vogrin, V Obeyesekere, C Sims, S Wyatt, G Ward, S McAuley, R MacIsaac, B Krishnamurthy, V Sundararajan, A Jenkins, D O'Neal

Conference Proceedings  |  2019  |  DIABETES TECHNOLOGY & THERAPEUTICS

HIGH-INTENSITY INTERVAL EXERCISE VS. MODERATE-INTENSITY EXERCISE IN ADULTS WITH TYPE 1 DIABETES AND IMPAIRED AWARENESS OF HYPOGLYCAEMIA USING CLOSED-LOOP INSULIN DELIVERY

M Lee, S Vogrin, B Paldus, H Jones, S McAuley, V Obeyesekere, J Gooley, R Giri, A La Gerche, R MacIsaac, V Sundararajan, A Jenkins, G Ward, D O'Neal

Conference Proceedings  |  2019  |  DIABETES TECHNOLOGY & THERAPEUTICS

A MODEL-BASED ALGORITHM DESIGN (MBAD) PLATFORM: FROM VIRTUAL-PATIENTS TO FEASIBILITY IN A SINGLE STEP

B Grosman, A Roy, D Wu, N Parikh, L Lintereur, P Weydt, A Dianaty, M Lee, V Obeyesekere, H Jone, DN O'Neal, FR Kaufman

Conference Proceedings  |  2019  |  DIABETES TECHNOLOGY & THERAPEUTICS

DRIVEN TO HYPERGLYCAEMIA: ADULTS WITH TYPE 1 DIABETES HAVE HIGHER GLUCOSE LEVELS WHEN DRIVING

S Trawley, S McAuley, M Lee, B Paldus, L Bach, M Burt, P Clarke, N Cohen, P Colman, M Debock, C Hendrieckx, D Holmes-Walker, A Jenkins, J Kaye, A Keech, K Kumareswaran, R Macisaac, R McCallum, C Sims, J Speight, et al.

Conference Proceedings  |  2019  |  DIABETES TECHNOLOGY & THERAPEUTICS

GLUCOSE TIME-IN-RANGE AFTER TYPE 1 DIABETES EDUCATION IS NOT DIFFERENT BETWEEN ADULTS USING INSULIN PUMPS AND MULTIPLE DAILY INJECTIONS

S McAuley, S Vogrin, M Lee, B Paldus, L Bach, M Burt, P Clarke, N Cohen, P Colman, M de Bock, C Hendrieckx, D Holmes-Walker, J Horsburgh, A Jenkins, J Kaye, A Keech, K Kumareswaran, R MacIsaac, R McCallum, C Sims, et al.

Conference Proceedings  |  2019  |  DIABETES TECHNOLOGY & THERAPEUTICS

GlycASSIST: a new tool to support treatment individualisation and intensification in the management of type 2 diabetes

Jo-Anne Manski-Nankervis, Brea Kunstler, Hamish McLachlan, Elizabeth Holmes-Truscott, Jane Speight, Gary Kilov, Mark Kennedy, Ralph Audehm, David O'Neal, Douglas Boyle, Ken Clark, Sophia Zoungas, Sean Lo, John Furler

Conference Proceedings  |  2019  |  AUSTRALIAN JOURNAL OF PRIMARY HEALTH

Glucose Control Using a Standard Versus an Enhanced Hybrid Closed Loop System: A Randomized Crossover Study

Barbora Paldus, Melissa H Lee, Hannah M Jones, Sybil A McAuley, Jodie C Horsburgh, Kerryn L Roem, Glenn M Ward, Richard J MacIsaac, Neale Cohen, Peter G Colman, Alicia J Jenkins, David N O'Neal

Journal article  |  2019  |  Diabetes Technology & Therapeutics

Associations between multimorbidity, all-cause mortality and glycaemia in people with type 2 diabetes: A systematic review

Jason I Chiang, Bhautesh Dinesh Jani, Frances S Mair, Barbara I Nicholl, John Furler, David O'Neal, Alicia Jenkins, Patrick Condron, Jo-Anne Manski-Nankervis

Journal article  |  2018  |  PLoS One

Introduction: Type 2 diabetes (T2D) is a major health priority worldwide and the majority of people with diabetes live with multim..

Insulin pumps in general practice

Barbora Paldus, Melissa H Lee, David N O'Neal

Journal article  |  2018  |  Australian Prescriber

Empagliflozin as an adjunctive therapy for type 1 diabetes

Richard J MacIsaac, Melissa H Lee, Sybil A McAuley, Glenn M Ward, David N O'Neal

Journal article  |  2018  |  Annals of Translational Medicine

Estimation of glucose disposal rate in type 1 diabetes using clinical and research biomarkers

AJ Jenkins, AS Januszewski, N Sachithanandan, G Ward, C Karschimkus, DN O'Neal

Conference Proceedings  |  2018  |  DIABETOLOGIA

MicroRNAs associated with insulin secretion in type 1 diabetes

AS Januszewski, M Joglekar, Y Cho, E Scott, R Farr, Y Loh, DN O'Neal, P Benitez-Aguirre, M Craig, K Donaghue, A Hardikar, AJ Jenkins

Conference Proceedings  |  2018  |  DIABETOLOGIA

Efficacy and safety of methionine aminopeptidase 2 inhibition in type 2 diabetes: a randomised, placebo-controlled clinical trial

Joseph Proietto, Jaret Malloy, Dongliang Zhuang, Mark Arya, Neale D Cohen, Ferdinandus J de Looze, Christopher Gilfillan, Paul Griffin, Stephen Hall, Thomas Nathow, Geoffrey S Oldfield, David N O'Neal, Adam Roberts, Bronwyn GA Stuckey, Dennis Yue, Kristin Taylor, Dennis Kim

Journal article  |  2018  |  Diabetologia

GP-OSMOTIC trial protocol: an individually randomised controlled trial to determine the effect of retrospective continuous glucose monitoring (r-CGM) on HbA1c in adults with type 2 diabetes in general practice

John Furler, David Norman O'Neal, Jane Speight, Irene Blackberry, Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Katie de La Rue, Louise Ginnivan, Jessica Lea Browne, Elizabeth Holmes-Truscott, Kamlesh Khunti, Kim Dalziel, Jason Chiang, Ralph Audehm, Mark Kennedy, Malcolm Clark, Alicia Josephine Jenkins, Danny Liew, Philip Clarke, James Best

Journal article  |  2018  |  BMJ OPEN

Suboptimal behaviour and knowledge regarding overnight glycaemia in adults with type 1 diabetes is common

Christina R Larsson, Andrzej S Januszewski, Rachel T McGrath, Johnny Ludvigsson, Anthony C Keech, Richard J MacIsaac, Glenn M Ward, David N O'Neal, Gregory R Fulcher, Alicia J Jenkins

Journal article  |  2018  |  Internal Medicine Journal

Effect of 6 months hybrid closed-loop insulin delivery in young people with type 1 diabetes: a randomised controlled trial protocol

Martin de Bock, Sybil A McAuley, Mary Binsu Abraham, Grant Smith, Jennifer Nicholas, Geoff R Ambler, Fergus J Cameron, Jan M Fairchild, Bruce R King, Elizabeth A Geelhoed, Elizabeth A Davis, David Norman O'Neal, Timothy W Jones

Journal article  |  2018  |  BMJ Open

Socioeconomic status and time in glucose target range in people with type 2 diabetes: a baseline analysis of the GP-OSMOTIC study

Mei Lyn Tan, Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Alicia Jenkins, David O'Neal, John Furler

Journal article  |  2018  |  BMC ENDOCRINE DISORDERS

Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: a randomised controlled trial protocol

Sybil A McAuley, Martin de Bock, Vijaya Sundararajan, Melissa H Lee, Barbora Paldus, Geoff R Ambler, Leon A Bach, Morton G Burt, Fergus J Cameron, Philip M Clarke, Neale D Cohen, Peter G Colman, Elizabeth A Davis, Jan M Fairchild, Christel Hendrieckx, D Jane Holmes-Walker, Jodie C Horsburgh, Alicia J Jenkins, Joey Kaye, Anthony C Keech, et al.

Journal article  |  2018  |  BMJ Open

Glucose Control Using a Standard vs. an Enhanced Hybrid Closed-Loop System—A Pilot Study

BARBORA PALDUS, MELISSA H LEE, HANNAH JONES, SYBIL A MCAULEY, JODIE C HORSBURGH, KERRYN L ROEM, GLENN WARD, RICHARD MACISAAC, NEALE COHEN, PETER G COLMAN, ALICIA JENKINS, DAVID N O'NEAL

Journal article  |  2018  |  Diabetes

Continuous glucose monitoring: a review of the evidence, opportunities for future use and ongoing challenges

Anna Wood, David O'Neal, John Furler, Elif I Ekinci

Journal article  |  2018  |  Internal Medicine Journal

Lipid-lowering therapy use and achievement of cholesterol targets in an Australian diabetes clinic

Katerina V Kiburg, Glenn M Ward, David N O'Neal, Richard J MacIsaac

Journal article  |  2018  |  Internal Medicine Journal

Impact of multimorbidity count on all-cause mortality and glycaemic outcomes in people with type 2 diabetes: a systematic review protocol

Jason I Chiang, John Furler, Frances S Mair, Bhautesh Jani, Barbara I Nicholl, Alicia Jenkins, Patrick Condron, David O'Neal, Jo-Anne Manski-Nankervis

Journal article  |  2018  |  BMJ OPEN

Introduction : Type 2 diabetes (T2D) is a leading health priority worldwide. Multimorbidity (MM) is a term describing the co-occur..

Initiating insulin in primary care

J Manski-Nankervis, J Furler, D O'Neal

Journal article  |  2018  |  Endocrinology Today

Predictors of insulin uptake among adults with type 2 diabetes in the Stepping Up Study

Elizabeth Holmes-Truscott, John Furler, Irene Blackberry, David N O'Neal, Jane Speight

Journal article  |  2017  |  Diabetes Research and Clinical Practice

Overcoming clinical inertia in insulin initiation in primary care for patients with type 2 diabetes: 24-month follow-up of the Stepping Up cluster randomised controlled trial

Jo-Anne Manski-Nankervis, John Furler, David O'Neal, Louise Ginnivan, Sharmala Thuraisingam, Irene Blackberry

Journal article  |  2017  |  Primary Care Diabetes

Lixisenatide reduces glycaemic variability in insulin-treated patients with type 2 diabetes

Guillermo E Umpierrez, David O'Neal, Andres DiGenio, Ronald Goldenberg, Eric Hernandez-Triana, Jay Lin, Cheol-Young Park, Eric Renard, Boris Kovatchev

Journal article  |  2017  |  Diabetes, Obesity and Metabolism

Asymmetric changes in circulating insulin levels after an increase compared with a reduction in insulin pump basal rate in people with Type 1 diabetes

SA McAuley, GM Ward, JC Horsburgh, JL Gooley, AJ Jenkins, RJ MacIsaac, DN O'Neal

Journal article  |  2017  |  Diabetic Medicine

Overnight Counter-Regulatory Hormone Levels and Next Day Glycemia in Adults with Type 1 Diabetes During Closed-Loop Insulin Delivery Versus Sensor-Augmented Pump with Low-Glucose Suspend

Anneke Graf, Glenn M Ward, Sara Vogrin, Vijaya Sundararajan, Amin Sharifi, Martin I De Bock, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Carolyn L Berthold, Nirubasini Paramalingam, Leon A Bach, Peter G Colman, Elizabeth A Davis, Benyamin Grosman, Alicia J Jenkins, Kavita Kumareswaran, Natalie Kurtz, Andrew Kyoong, Richard J MacIsaac, et al.

Journal article  |  2017  |  Diabetes Technology & Therapeutics

"It Is Definitely a Game Changer'': A Qualitative Study of Experiences with In-home Overnight Closed-Loop Technology Among Adults with Type 1 Diabetes

Christel Hendrieckx, Lucinda A Poole, Amin Sharifi, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Leon A Bach, Peter G Colman, Kavita Kumareswaran, Alicia J Jenkins, Richard J MacIsaac, Glenn M Ward, Benyamin Grosman, Anirban Roy, David N O'Neal, Jane Speight

Journal article  |  2017  |  Diabetes Technology & Therapeutics

Closed-Loop Insulin Delivery for Adults with Type 1 Diabetes Undertaking High-Intensity Interval Exercise Versus Moderate-Intensity Exercise: A Randomized, Crossover Study

Dilshani C Jayawardene, Sybil A McAuley, Jodie C Horsburgh, Andre La Gerche, Alicia J Jenkins, Glenn M Ward, Richard J Maclsaac, Timothy J Roberts, Benyamin Grosman, Natalie Kurtz, Anirban Roy, David N O'Neal

Journal article  |  2017  |  Diabetes Technology & Therapeutics

Supporting insulin initiation in type 2 diabetes in primary care: results of the Stepping Up pragmatic cluster randomised controlled clinical trial

John Furler, David O'Neal, Jane Speight, Jo-Anne Manski-Nankervis, Alexandra Gorelik, Elizabeth Holmes-Truscott, Louise Ginnivan, Doris Young, James Best, Elizabeth Patterson, Danny Liew, Leonie Segal, Carl May, Irene Blackberry

Journal article  |  2017  |  BMJ

Moving Toward a Unified Platform for Insulin Delivery and Sensing of Inputs Relevant to an Artificial Pancreas.

Anneke Graf, Sybil A McAuley, Catriona Sims, Johanna Ulloa, Alicia J Jenkins, Gayane Voskanyan, David N O'Neal

Journal article  |  2017  |  Journal of Diabetes Science and Technology

Advances in insulin pump and continuous glucose monitoring technology have primarily focused on optimizing glycemic control for pe..

Factors associated with duration of inpatient hospital stay for patients with diabetes mellitus admitted to a medical unit in a community public hospital

Melissa H Lee, Lillianne Liprino, Jeffrey Brooks, Brenda Cayzer, Fiona Weedon, Kate Bermingham, Alicia J Jenkins, Kevin Rowley, David N O'Neal

Journal article  |  2017  |  Australian Journal of Primary Health

John Furler - thanks and best wishes

Melissa H Lee, Lillianne Liprino, Jeffrey Brooks, Brenda Cayzer, Fiona Weedon, Kate Bermingham, Alicia J Jenkins, Kevin Rowley, David N O'Neal

Journal article  |  2017  |  Australian Journal of Primary Health

Glycemia, Treatment Satisfaction, Cognition, and Sleep Quality in Adults and Adolescents with Type 1 Diabetes When Using a Closed-Loop System Overnight Versus Sensor-Augmented Pump with Low-Glucose Suspend Function: A Randomized Crossover Study

Amin Sharifi, Martin I De Bock, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Carolyn L Berthold, Nirubasini Paramalingam, Leon A Bach, Peter G Colman, Elizabeth A Davis, Benyamin Grosman, Christel Hendrieckx, Alicia J Jenkins, Kavita Kumareswaran, Natalie Kurtz, Andrew Kyoong, Richard J MacIsaac, Jane Speight, Steven Trawley, Glenn M Ward, et al.

Journal article  |  2016  |  Diabetes Technology & Therapeutics

Peripheral neuropathy in the hands of people with diabetes mellitus

Samantha L Ennis, Mary P Galea, David N O'Neal, Michael J Dodson

Journal article  |  2016  |  Diabetes Research and Clinical Practice

Insulin pump basal adjustment for exercise in type 1 diabetes: a randomised crossover study

Sybil A McAuley, Jodie C Horsburgh, Glenn M Ward, Andre La Gerche, Judith L Gooley, Alicia J Jenkins, Richard J MacIsaac, David N O'Neal

Journal article  |  2016  |  Diabetologia

Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report

David M Maahs, Bruce A Buckingham, Jessica R Castle, Ali Cinar, Edward R Damiano, Eyal Dassau, J Hans DeVries, Francis J Doyle, Steven C Griffen, Ahmad Haidar, Lutz Heinemann, Roman Hovorka, Timothy W Jones, Craig Kollman, Boris Kovatchev, Brian L Levy, Revital Nimri, David N O'Neal, Moshe Philip, Eric Renard, et al.

Journal article  |  2016  |  Diabetes Care

Shorter telomeres in adults with Type 1 diabetes correlate with diabetes duration, but only weakly with vascular function and risk factors

Andrzej S Januszewski, Surya S Sutanto, Susan McLennan, David N O'Neal, Anthony C Keech, Stephen M Twigg, Alicia J Jenkins

Journal article  |  2016  |  Diabetes Research and Clinical Practice

Impact of insulin initiation on glycaemic variability and glucose profiles in a primary healthcare Type 2 diabetes cohort: analysis of continuous glucose monitoring data from the INITIATION study

J Manski-Nankervis, CJ Yates, I Blackberry, J Furler, L Ginnivan, N Cohen, A Jenkins, S Vasanthakumar, A Gorelik, D Young, J Best, D O'Neal

Journal article  |  2016  |  Diabetic Medicine

Feasibility of an Orthogonal Redundant Sensor incorporating Optical plus Redundant Electrochemical Glucose Sensing.

Sybil A McAuley, Tri T Dang, Jodie C Horsburgh, Anubhuti Bansal, Glenn M Ward, Sarkis Aroyan, Alicia J Jenkins, Richard J MacIsaac, Rajiv V Shah, David N O'Neal

Journal article  |  2016  |  Journal of Diabetes Science and Technology

BACKGROUND: Orthogonal redundancy for glucose sensing (multiple sensing elements utilizing distinct methodologies) may enhance per..

Redundancy in Glucose Sensing: Enhanced Accuracy and Reliability of an Electrochemical Redundant Sensor for Continuous Glucose Monitoring.

Amin Sharifi, Andrea Varsavsky, Johanna Ulloa, Jodie C Horsburgh, Sybil A McAuley, Balasubramanian Krishnamurthy, Alicia J Jenkins, Peter G Colman, Glenn M Ward, Richard J MacIsaac, Rajiv Shah, David N O'Neal

Journal article  |  2016  |  Journal of Diabetes Science and Technology

BACKGROUND: Current electrochemical glucose sensors use a single electrode. Multiple electrodes (redundancy) may enhance sensor pe..

Willingness to initiate insulin among adults with type 2 diabetes in Australian primary care: Results from the Stepping Up Study

Elizabeth Holmes-Truscott, Irene Blackberry, David N O'Neal, John S Furler, Jane Speight

Journal article  |  2016  |  Diabetes Research and Clinical Practice

Healthcare professional requirements for the care of adult diabetes patients managed with insulin pumps in Australia

S Xu, K Alexander, W Bryant, N Cohen, ME Craig, M Forbes, G Fulcher, T Greenaway, N Harrison, DJ Holmes-Walker, G Howard, J Jackson, A Jenkins, M Kamp, J Kaye, A Sinha, S Stranks, D O'Neal, P Colman

Journal article  |  2015  |  Internal Medicine Journal

Relational coordination amongst health professionals involved in insulin initiation for people with type 2 diabetes in general practice: an exploratory survey

Jo-Anne Manski-Nankervis, Irene Blackberry, Doris Young, David O'Neal, Elizabeth Patterson, John Furler

Journal article  |  2014  |  BMC HEALTH SERVICES RESEARCH

New Treatments for Type 2 Diabetes: Cardiovascular Protection Beyond Glucose Lowering?

Dilshani Jayawardene, Glenn M Ward, David N O'Neal, Geetha Theverkalam, Andrew I MacIsaac, Richard J MacIsaac

Journal article  |  2014  |  Heart, Lung and Circulation

An exploratory trial of basal and prandial insulin initiation and titration for type 2 diabetes in primary care with adjunct retrospective continuous glucose monitoring: INITIATION study

Irene D Blackberry, John S Furler, Louise E Ginnivan, Jo-Anne Manski-Nankervis, Alicia Jenkins, Neale Cohen, James D Best, Doris Young, Danny Liew, Glenn Ward, David N O'Neal

Journal article  |  2014  |  DIABETES RESEARCH AND CLINICAL PRACTICE

Plasma semicarbazide-sensitive amine oxidase activity in type 1 diabetes is related to vascular and renal function but not to glycaemia

Andrzej S Januszewski, Nick Mason, Connie S Karschimkus, Kevin G Rowley, James D Best, David N O'Neal, Alicia J Jenkins

Journal article  |  2014  |  Diabetes and Vascular Disease Research

Stepping up: a nurse-led model of care for insulin initiation for people with type 2 diabetes

John S Furler, Irene D Blackberry, Christine Walker, Jo-Anne Manski-Nankervis, Jenny Anderson, David O'Neal, Doris Young, James Best

Journal article  |  2014  |  Family Practice

An exploratory trial of insulin initiation and titration among patients with type 2 diabetes in the primary care setting with retrospective continuous glucose monitoring as an adjunct: INITIATION study protocol

Irene D Blackberry, John S Furler, Louise E Ginnivan, Hanan Derraz, Alicia Jenkins, Neale Cohen, James D Best, Doris Young, Danny Liew, Glenn Ward, Jo-Anne Manski-Nankervis, David N O'Neal

Journal article  |  2014  |  BMC FAMILY PRACTICE

Can primary care team-based transition to insulin improve outcomes in adults with type 2 diabetes: the stepping up to insulin cluster randomized controlled trial protocol

John S Furler, Doris Young, James Best, Elizabeth Patterson, David O'Neal, Danny Liew, Jane Speight, Leonie Segal, Carl May, Jo-Anne Manski-Nankervis, Elizabeth Holmes-Truscott, Louise Ginnivan, Irene D Blackberry

Journal article  |  2014  |  IMPLEMENTATION SCIENCE

Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes

Peter J Little, Alan Chait, Andrzej S Januszewski, Alex Bobik, David O'Neal, Alicia J Jenkins

Book Chapter  |  2014

Optimizing care and outcomes for people with type 2 diabetes - lessons from a translational research program on insulin initiation in general practice.

John Furler, Irene Blackberry, Jo-Anne Manski-Nankervis, David O'Neal, James Best, Doris Young

Journal article  |  2014  |  Front Med (Lausanne)

BACKGROUND: Clinical inertia, failure to intensify treatment according to evidence-based guidelines, leads to prolonged, avoidable..

Management of treatment resistant hypertension in diabetes

G Theverkalam, DN O'Neal, GM Ward, G Jerums, EI Ekinci, RJ MacIsaac

Journal article  |  2014  |  Diabetes Management

The Role of Real Time Continuous Glucose Monitoring in People with Diabetes Managed with Multiple Daily Injections: Need for Future Research

A SHARIFI, Sybil McAuley, J Horsburgh, M Loh, A Jenkins, R MacIsaac, D O'Neal

Journal article  |  2014  |  Infusystems Asia

Feasibility of adjacent insulin infusion and continuous glucose monitoring via the Medtronic Combo-Set.

David N O'Neal, Sumona Adhya, Alicia Jenkins, Glenn Ward, John B Welsh, Gayane Voskanyan

Journal article  |  2013  |  Journal of Diabetes Science and Technology

BACKGROUND: Subcutaneously infused insulin may interfere with the function of nearby glucose-sensing electrodes and vice versa. Th..

TIME TO STEADY-STATE CIRCULATING INSULIN LEVELS FOLLOWING INSULIN PUMP BASAL INSULIN INFUSION RATE CHANGES IN ADULTS WITH TYPE 1 DIABETES

SA McAuley, JC Horsburgh, GM Ward, JL Gooley, AJ Jenkins, RJ MacIsaac, DN O'Neal

Conference Proceedings  |  2013  |  DIABETES TECHNOLOGY & THERAPEUTICS

TYPE 1 DIABETES ADULTS USING CSII HAVE HIGHER VASCULAR ELASTICITY AND LESS INFLAMMATION THAN TYPE 1 DIABETES ADULTS USING MULTIPLE DAILY INSULIN INJECTIONS

A Jenkins, A Januszewski, C Karschimkus, S McAuley, D Calandro, D O'Neal

Conference Proceedings  |  2013  |  DIABETES TECHNOLOGY & THERAPEUTICS

Feasibility of adjacent insulin infusion and glucose sensing via the Combo-set

DN O'Neal, S Adhya, A Jenkins, G Ward, JB Welsh, G Voskanyan

Conference Proceedings  |  2012  |  DIABETOLOGIA

Non-invasive measures of tissue autofluorescence are increased in Type 1 diabetes complications and correlate with a non-invasive measure of vascular dysfunction

AS Januszewski, N Sachithanandan, C Karschimkus, DN O'Neal, CK Yeung, N Alkatib, AJ Jenkins

Journal article  |  2012  |  Diabetic Medicine

Plasma 1,5 anhydroglucitol levels, a measure of short-term glycaemia: Assay assessment and lower levels in diabetic vs. non-diabetic subjects

Andrzej S Januszewski, Connie Karschimkus, Kathryn ER Davis, David O'Neal, Glenn Ward, Alicia J Jenkins

Journal article  |  2012  |  Diabetes Research and Clinical Practice

The Evidence Gap for Clinical Decisions Regarding Insulin Pump Basal Regimens

Sybil McAuley, Glenn Ward, jodie Horsburgh, alicia Jenkins, R MacIsaac, D O'Neal

Journal article  |  2012  |  Infusystems Asia

An Algorithm Guiding Patient Responses to Real-Time-Continuous Glucose Monitoring Improves Quality of Life

Alicia J Jenkins, Balasubramanian Krishnamurthy, James D Best, Fergus J Cameron, Peter G Colman, Peter S Hamblin, Michele A O'Connell, Christine Rodda, Helena Teede, David N O'Neal

Journal article  |  2011  |  Diabetes Technology & Therapeutics

Increased serum kallistatin levels in type 1 diabetes patients with vascular complications.

Alicia J Jenkins, Jeffrey D McBride, Andrzej S Januszewski, Connie S Karschimkus, Bin Zhang, David N O'Neal, Craig L Nelson, Jasmine S Chung, C Alex Harper, Timothy J Lyons, Jian-Xing Ma

Journal article  |  2010  |  Journal of Angiogenesis Research

BACKGROUND: Kallistatin, a serpin widely produced throughout the body, has vasodilatory, anti-angiogenic, anti-oxidant, and anti-i..

Evaluation of an Algorithm to Guide Patients With Type 1 Diabetes Treated With Continuous Subcutaneous Insulin Infusion on How to Respond to Real-Time Continuous Glucose Levels A randomized controlled trial

Alicia J Jenkins, Balasubramanium Krishnamurthy, James D Best, Fergus Cameron, Peter G Colman, Steven Farish, Peter S Hamblin, Michele A O'Connell, Christine Rodda, Kevin Rowley, Helena Teede, David N O'Neal

Journal article  |  2010  |  Diabetes Care

Lipid treatment guidelines and cardiovascular risk for Aboriginal people in Central Australia

Joanne N Luke, Alex Brown, David N O'Neal, Kerin O'Dea, Alicia J Jenkins, Margaret Kelaher, James D Best, Kevin G Rowley

Journal article  |  2009  |  Medical Journal of Australia

Australian Aboriginal people and Torres Strait Islanders have an atherogenic lipid profile that is characterised by low HDL-cholesterol level and small LDL particles

DN O'Neal, LS Piers, DM Iser, KG Rowley, AJ Jenkins, JD Best, K O'Dea

Journal article  |  2008  |  Atherosclerosis

Glutathionyl haemoglobin is not increased in diabetes nor related to glycaemia, complications, dyslipidaemia, inflammation or other measures of oxidative stress.

Peter Hoffmann, Jade Woon, Kevin G Rowley, Connie Karschimkus, Craig L Nelson, George Dragicevic, David O'Neal, Andrew Wilson, Kevin D Croft, Trevor A Mori, Bruce E Kemp, James D Best, Alicia J Jenkins

Journal article  |  2008  |  Diabetes Research and Clinical Practice

Modified haemoglobin levels were quantified in 21 Type 1 and 21 Type 2 diabetic patients and two groups of 17 non-diabetic subject..

Longitudinal analysis of low-molecular weight fluorophores in type 1 diabetes mellitus.

Andrzej S Januszewski, Merlin C Thomas, Connie S Karschimkus, Jasmine S Chung, Kevin G Rowley, Craig L Nelson, David N O'Neal, George Dragicevic, Colin A Harper, James D Best, Alicia J Jenkins

Journal article  |  2008  |  Journal of Medical Investigation

OBJECTIVES: Circulating low molecular weight (<10 kDa) fluorophores (LMW-F) measured by non-specific fluorescence spectroscopy may..

Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes

AJ Jenkins, SX Zhang, KG Rowley, CS Karschimkus, CL Nelson, JS Chung, DN O'Neal, AS Januszewski, KD Croft, TA Mori, G Dragicevic, CA Harper, JD Best, TJ Lyons, J-X Ma

Journal article  |  2007  |  Diabetic Medicine

The role of continuous glucose monitoring in clinical decision-making in diabetes in pregnancy

Kylie McLachlan, Alicia Jenkins, David O'Neal

Journal article  |  2007  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

The Role of and the Principles involved in Interpreting Continuous Glucose Monitoring Data in Implementing Changes in the Management of Diabetic Patients on Continuous Subcutaenous Insulin Infusion Therapy

A JENKINS, D O'NEAL

Journal article  |  2007  |  Infusystems Asia

Severe combined hyperlipidaemia and retinal lipid infiltration in a patient with Type 2 diabetes mellitus

Rachel A Davey, Niall C Tebbutt, Jenny M Favaloro, David N O'Neal, Derek Rae, Jeffrey D Zajac, James D Best

Journal article  |  2006  |  Lipids in Health and Disease

Do adiponectin, TNF alpha, leptin and CRP retate to insulin resistance in pregnancy? Studies in women with and without gestational diabetes, during and after pregnancy

KA McLachlan, D O'Neal, A Jenkins, FP Alford

Journal article  |  2006  |  Diabetes-Metabolism Research and Reviews

Systemic and vascular inflammation is elevated in early IgA and type 1 diabetic nephropathies and relates to vascular disease risk factors and renal function

CL Nelson, CS Karschimkus, G Dragicevic, DK Packham, AM Wilson, D O'Neal, GJ Becker, JD Best, AJ Jenkins

Journal article  |  2005  |  Nephrology, Dialysis, Transplantation

Plasma low-molecular weight fluorescence in type 1 diabetes mellitus

AS Januszewski, MC Thomas, SJ Chung, CS Karschimkus, KG Rowley, C Nelson, D O'Neal, Z Wang, JD Best, AJ Jenkins

Journal article  |  2005  |  Annals of The New York Academy of Sciences

Comparison of arterial assessments in low and high vascular disease risk groups

AM Wilson, D O'Neal, CL Nelson, DL Prior, JD Best, AJ Jenkins

Journal article  |  2004  |  American Journal of Hypertension

Octreotide treatment of severe diabetic diarrhoea

C Meyer, DN O'Neal, W Connell, F Alford, G Ward, AJ Jenkins

Journal article  |  2003  |  Internal Medicine Journal

Inflammation and vascular endothelial activation in an Aboriginal population: relationships to coronary disease risk factors and nutritional markers

K Rowley, KZ Walker, J Cohen, AJ Jenkins, D O'Neal, Q Su, JD Best, K O'Dea

Journal article  |  2003  |  Medical Journal of Australia

Bacteremia due to three Bacillus species in a case of Munchausen's syndrome

J Galanos, S Perera, H Smith, D O'Neal, H Sheorey, MJ Waters

Journal article  |  2003  |  Journal of Clinical Microbiology

A cross-sectional study of the effects of type 2 diabetes and other cardiovascular risk factors on structure and function of nonstenotic arteries of the lower limb

DN O'Neal, N Balazs, G Dragicevic, A Jenkins, KG Rowley, JD Best, MZ Ansari

Journal article  |  2003  |  Diabetes Care

Diabetic dyslipidaemia - Current treatment recommendations

JD Best, DN O'Neal

Journal article  |  2000  |  Drugs

Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men

TA Mori, V Burke, IB Puddey, GF Watts, DN O 'Neal, JD Best, LJ Beilin

Journal article  |  2000  |  The American Journal of Clinical Nutrition

Treating elevated lipids. Does it make a difference?

J Best, D O'Neal

Journal article  |  2000  |  Australian family physician

BACKGROUND: There is now abundant evidence from clinical trials that treatment with lipid modifying therapy will decrease the risk..

The effect of 24 months recombinant human growth hormone (rh-GH) on LDL cholesterol, triglyceride-rich lipoproteins and apo [a] in hypopituitary adults previously treated with conventional replacement therapy

DN O'Neal, FL Hew, JD Best, F Alford

Journal article  |  1999  |  Growth Hormone & IGF Research

Gemfibrozil treatment increases low-density lipoprotein particle size in type 2 diabetes mellitus but does not alter in vitro oxidizability

DN O'Neal, RC O'Brien, KL Timmins, GD Grieve, KP Lau, GC Nicholson, MA Kotowicz, JD Best

Journal article  |  1998  |  Diabetic Medicine

A comparison of LDL size determination using gradient gel electrophoresis and light-scattering methods

D O'Neal, P Harrip, G Dragicevic, D Rae, JD Best

Journal article  |  1998  |  Journal of Lipid Research

Growth hormone deficiency and cardiovascular risk

JD Best, D O'Neal, N Kamarudin, FP Alford, JD Best

Journal article  |  1998  |  Baillière's Clinical Endocrinology and Metabolism

Lipid levels and peripheral vascular disease in diabetic and non-diabetic subjects

DN O'Neal, J Lewicki, MZ Ansari, PG Matthews, JD Best

Journal article  |  1998  |  Atherosclerosis

Low-density lipoprotein size, high-density lipoprotein concentration, and endothelial dysfunction in non-insulin-dependent diabetes.

SF O'Brien, GF Watts, DA Playford, V Burke, DN O'Neal, JD Best

Journal article  |  1997  |  Diabetic Medicine

We examined endothelial function (nitric-oxide mediated) in 29 men with diet-treated non-insulin-dependent (Type 2) diabetes melli..

The role of abdominal adiposity and insulin resistance in dyslipidemia of chronic renal failure

P Lee, D ONeal, B Murphy, J Best

Journal article  |  1997  |  American Journal of Kidney Diseases

Guiding glucose management discussions with adults with type 2 diabetes in general practice: The development and pre-testing of a prototype clinical decision support tool embedded in the electronic medical record. (Preprint)

Brea E Kunstler, John Furler, Elizabeth Holmes-Truscott, Hamish McLachlan, Douglas Boyle, Sean Lo, Jane Speight, David O'Neal, Ralph Audehm, Gary Kilov, Jo-Anne Manksi-Nankervis

Journal article  |  JMIR Formative Research

A prototype clinical decision support tool embedded in the electronic medical record to guide glucose management discussions with adults with type 2 diabetes in general practice: Development and pre-testing using codesign. (Preprint)

Brea E Kunstler, John Furler, Elizabeth Holmes-Truscott, Hamish McLachlan, Douglas Boyle, Sean Lo, Jane Speight, David O'Neal, Ralph Audehm, Gary Kilov, Jo-Anne Manksi-Nankervis

Journal article

BACKGROUND Managing type 2 diabetes (T2D) requires progressive lifestyle change and pharmacological treatm..