Robb de Iongh

Epha2 genotype influences ultraviolet radiation induced cataract in mice

Alpana Dave, Jamie E Craig, Karina Skrzypiec, Stephen Quinn, Mary Barnes, Nick Di Girolamo, David A Mackey, Kathryn P Burdon, Robb U de Iongh, Shiwani Sharma

Journal article  |  2019  |  Experimental Eye Research

Age-related cataract is the major cause of blindness worldwide. Both genetic and environmental factors contribute to the disease. ..

Altered airway ciliary orientation in patients with X-linked retinitis pigmentosa

Gabrielle McCray, Paul Griffin, Paul Martinello, Robb de Iongh, Jonathan Ruddle, Phil Robinson

Journal article  |  2019  |  Thorax

Previous reports suggested links between respiratory ciliary dysfunction and primary ciliopathies such as X-linked retinitis pigme..

Exposure of trophoblast cells to fine particulate matter air pollution leads to growth inhibition, inflammation and ER stress

Mary Familari, Asa Naav, Lena Erlandsson, Robb U de Iongh, Christina Isaxon, Bo Strandberg, Thomas Lundh, Stefan R Hansson, Ebba Malmqvist

Journal article  |  2019  |  PLOS ONE

Ambient air pollution is considered a major environmental health threat to pregnant women. Our previous work has shown an associat..

FINE PARTICULATE MATTER AIR POLLUTION CAUSES INFLAMMATION, ER STRESS AND ACTIVATES CELL DEATH IN CULTURED FIRST TRIMESTER TROPHOBLAST

Stefan R Hansson, Mary Familari, Asa Naav, Lena Erlandsson, Robb de Longh, Christina Isaxon, Ebba Malmqvist

Conference Proceedings  |  2018  |  PLACENTA

Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis

Shaghayegh Saeidi, Farnaz Shapouri, Robb U de Iongh, Franca Casagranda, Jessie M Sutherland, Patrick S Western, Eileen A McLaughlin, Mary Familari, Gary R Hime

Journal article  |  2018  |  PLOS ONE

Tob1 and Tob2 mark distinct RNA processing granules in differentiating lens fibre cells

Robbert De Iongh, Rafaela Perez, Mary Familari, Gemma Martinez, Frank J Lovicu, Gary Hime

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Altered SOX9 genital tubercle enhancer region in hypospadias

Rajini Sreenivasan, Christopher T Gordon, Sabina Benko, Robb De Iongh, Stefan Bagheri-Fam, Stanislas Lyonnet, Vincent Harley

Journal article  |  2017  |  The Journal of Steroid Biochemistry and Molecular Biology

The role of pro-apoptotic proteins Bak and Bax in rd1 rodent model of retinitis pigmentosa

Kiana Kakavand, Andrew Ian Jobling, Robbert De Iongh, Stephane Chappaz, Benjamin T Kyle, Erica L Fletcher

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Localization and Possible Function of P2X Receptors in Normal and Diseased Retinae

Tracy Ho, Felix P Aplin, Andrew I Jobling, Joanna A Phipps, Robb U de Iongh, Ursula Greferath, Kirstan A Vessey, Erica L Fletcher

Journal article  |  2016  |  Journal of Ocular Pharmacology and Therapeutics

Tob1 is expressed in developing and adult gonads and is associated with the P-body marker, Dcp2

Farnaz Shapouri, Shaghayegh Saeidi, Robb U de Iongh, Franca Casagranda, Patrick S Western, Eileen A McLaughlin, Jessie M Sutherland, Gary R Hime, Mary Familari

Journal article  |  2016  |  Cell and Tissue Research

The role of ESRP1 during gametogenesis

Seyedeh Shaghayegh Saeidi, Farnaz Shapouri, Robb De Iongh, Franca Casagranda, Patrick Western, Eileen McLaughlin, Jessie Sutherland, Mary Familari, Gary Hime

Conference Proceedings  |  2016  |  CLINICAL ENDOCRINOLOGY

Tob1 protein is a novel regulator of gonadal function

Farnaz Shapouri, Seyedeh Shaghayegh Saeidi, Robb De Iongh, Franca Casagranda, Patrick S Western, Eileen McLaughlin, Jessie Sutherland, Gary Hime, Mary Familari

Conference Proceedings  |  2016  |  CLINICAL ENDOCRINOLOGY

Expression analysis of Cdx2 and Pou5f1 in a marsupial, the stripe-faced dunnart, during early development

Mary Familari, Phil Chi Khang Au, Robb U De Iongh, Yolanda Cruz, Lynne Selwood

Journal article  |  2016  |  Molecular Reproduction and Development

Inner retinal change in a novel rd1-FTL mouse model of retinal degeneration

Ursula Greferath, Emily E Anderson, Andrew I Jobling, Kirstan A Vessey, Gemma Martinez, Robb U de Iongh, Michael Kalloniatis, Erica L Fletcher

Journal article  |  2015  |  Frontiers in Cellular Neuroscience

A Role for Smoothened during Murine Lens and Cornea Development

Janet JY Choi, Chao-Tung Ting, Lidia Trogrlic, Stefan V Milevski, Mary Familari, Gemma Martinez, Robb U de Iongh

Journal article  |  2014  |  PLoS ONE

Adenosine Triphosphate-Induced Photoreceptor Death and Retinal Remodeling In Rats

Kirstan A Vessey, Ursula Greferath, Felix P Aplin, Andrew I Jobling, Joanna A Phipps, Tracy Ho, Robbert U De Iongh, Erica L Fletcher

Journal article  |  2014  |  Journal of Comparative Neurology

Studying Age-Related Macular Degeneration Using Animal Models

Erica L Fletcher, Andrew I Jobling, Ursula Greferath, Samuel A Mills, Michelle Waugh, Tracy Ho, Robb U de Iongh, Joanna A Phipps, Kirstan A Vessey

Journal article  |  2014  |  Optometry and Vision Science

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation

Zhi Ling Teo, Lachlan McQueen-Miscamble, Kirsty Turner, Gemma Martinez, Bhavani Madakashira, Shoukat Dedhar, Michael L Robinson, Robb U de Longh

Journal article  |  2014  |  Experimental Eye Research

Growth factor signaling in lens fiber differentiation

RU De Iongh, MK Duncan

Book Chapter  |  2014

Growth factor signaling in lens fiber differentiation

R DE IONGH, MK Duncan

Book Chapter  |  2014

A POTENTIAL ROLE FOR HEDGEHOG SIGNALLING DURING LENS AND CORNEAL DEVELOPMENT

RU de Iongh, JY Choi, CT Ting, G Martinez

Conference Proceedings  |  2013  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Restricted period of Smoothened requirement during lens development

Robbert De Iongh, Chaotung Ting, Jing Yee Janet Choi, Gemma Martinez

Conference Proceedings  |  2013  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Understanding the role of growth factors in embryonic development: insights from the lens

FJ Lovicu, JW McAvoy, RU de Iongh

Journal article  |  2011  |  Royal Society of London. Proceedings B. Biological Sciences

The lens epithelium in ocular health and disease

G Martinez, RU de Iongh

Journal article  |  2010  |  International Journal of Biochemistry and Cell Biology

A Requirement for FGF Signalling in the Formation of Primitive Streak-Like Intermediates from Primitive Ectoderm in Culture

Zhiqiang Zheng, Robb U de Iongh, Peter D Rathjen, Joy Rathjen

Journal article  |  2010  |  PLoS One

Marsupial Milk - Identifying Signals for Regulating Mammary Function and Development of the Young

Julie A Sharp, Christophe Lefevre, Joly Kwek, Denijal Topcic, Laurine Buscara, Cate Pooley, Robb de Iongh, Mary Familari, Kevin R Nicholas

Book Chapter  |  2010

Conditional Mutations of beta-Catenin and APC Reveal Roles for Canonical Wnt Signaling in Lens Differentiation

Gemma Martinez, Mary Wijesinghe, Kirsty Turner, Helen E Abud, Makoto M Taketo, Tetsuo Noda, Michael L Robinson, Robb U de Iongh

Journal article  |  2009  |  Investigative Ophthalmology and Visual Science

Molecular Insights Into Evolution of the Vertebrate Gut: Focus on Stomach and Parietal Cells in the Marsupial, Macropus eugenii

Joly Kwek, Robbert De Iongh, Kevin Nicholas, Mary Familari

Journal article  |  2009  |  Journal of Experimental Zoology. Part B: Molecular and Developmental Evolution

Cross-fostering of the tammar wallaby (Macropus eugenii) pouch young accelerates fore-stomach maturation

Joly HL Kwek, Robbert De Iongh, Matthew R Digby, Marilyn B Renfree, Kevin R Nicholas, Mary Familari

Journal article  |  2009  |  Mechanisms of Development

Respiratory Ciliary Dysfunction

J Rutland, L Morgan, R de Iongh

Book Chapter  |  2008

Differential requirement for beta-catenin in epithelial and fiber cells during lens development

Sarah Cain, Gemma Martinez, Maria I Kokkinos, Kirsty Turner, Robert J Richardson, Helen E Abud, Joerg Huelsken, Michael L Robinson, Robb U de Iongh

Journal article  |  2008  |  Developmental Biology

Generation of transparency and cellular organization in lens explants

Michael D O'Connor, Elizabeth D Wederell, Robert de Iongh, Frank J Lovicu, John W McAvoy

Journal article  |  2008  |  Experimental Eye Research

Osmic acid staining of myelin sheath in normal and regenerated peripheral nerves.

Li-ping Wei, Feng-chun He, Xun-wen Chen, Shi-bi Lu, Marco Lanzetta, Robbert De Iongh

Journal article  |  2007  |  Chinese Journal of Traumatology

OBJECTIVE: To introduce a practical, economical, and time-saving method to stain (with osmic acid) the myelin sheath in normal and..

Focal adhesion kinase (FAK) expression and activation during lens development

Maria I Kokkinos, Heidi J Brown, Robbert U de Iongh

Journal article  |  2007  |  Molecular Vision

Extracellular matrix and integrin signaling in lens development and cataract

Elizabeth D Wederell, Robb U de Iongh

Journal article  |  2006  |  Seminars in Cell & Developmental Biology

Mutations of DNAI1 in primary ciliary dyskinesia - Evidence of founder effect in a common mutation

Maimoona A Zariwala, Margaret W Leigh, Franck Ceppa, Marcus P Kennedy, Peadar G Noone, Johnny L Carson, Milan J Hazucha, Adriana Lori, Judit Horvath, Heike Olbrich, Niki T Loges, Anne-Marie Bridoux, Gaelle Pennarun, Benedicte Duriez, Estelle Escudier, Hannah M Mitchison, Rahul Chodhari, Eddie MK Chung, Lucy C Morgan, Robbert U de Iongh, et al.

Journal article  |  2006  |  American Journal of Respiratory and Critical Care Medicine

WNT/Frizzled signaling in eye development and disease

Robb U de Iongh, Helen E Abud, Gary R Hime

Journal article  |  2006  |  Frontiers in Bioscience

Laminin-binding integrins in rat lens morphogenesis and their regulation during fibre differentiation

ED Wederell, H Brown, M O'Connor, CG Chamberlain, JW McAvoy, RU de Iongh

Journal article  |  2005  |  Experimental Eye Research

Differential requirement for b-catenin in epithelial and fibre cells during lens differentiation

R De Iongh, S Cain, HE Abud, MI Kokkinos, J Huelsken, ML Robinson

Conference Proceedings  |  2005  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Transforming growth factor-beta-induced epithelial-mesenchymal transition in the lens: A model for cataract formation

RU de Iongh, E Wederell, FJ Lovicu, JW McAvoy

Journal article  |  2005  |  Cells Tissues Organs

BMP and activin receptor expression in lens development

R de Iongh, Y Chen, M Kokkinos, J McAvoy

Journal article  |  2004  |  Molecular Vision

Scintigraphic measurement of tracheal mucus velocity in vivo

L Morgan, M Pearson, R de longh, D Mackey, H van der Wall, M Peters, J Rutland

Journal article  |  2004  |  European Respiratory Journal

Modulation of mucociliary function by drugs and other agents

J Rutland, L Morgan, R De Iongh

Book Chapter  |  2004

042.The role of TGF-β in normal and pathological lens development

JW McAvoy, FJ Lovicu, RU De Iongh

Journal article  |  2004  |  Reproduction, Fertility and Development

How the lens develops its highly ordered architecture and growth patterns is a major question in developmental biology. During emb..

A role for Wnt/beta-catenin signaling in lens epithelial differentiation

RJW Stump, S Ang, YJ Chen, T von Bahr, FJ Lovicu, K Pinson, RU de Iongh, TP Yamaguchi, DA Sassoon, JW McAvoy

Journal article  |  2003  |  Developmental Biology

Long-term result of guided nerve regeneration with an inert microporous polytetrafluoroethylene conduit.

Feng-chun He, Qing-yu Fan, Timothy R Cushway, Robbert De Iongh, Marco Lanzetta, Pierluigi Tos, Earl R Owen

Journal article  |  2003  |  Chinese Journal of Traumatology

OBJECTIVE: To evaluate the long-term outcome of Polytetrafluoroethylene (PTFE) conduit in nerve repair and to provide more evidenc..

Expression of focal adhesion kinase (FAK) in the murine lens

R De Iongh, H Brown, JW McAvoy

Conference Proceedings  |  2003  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Expression of BMP and activin receptors during lens development

Y Chen, JW McAvoy, R de Iongh

Conference Proceedings  |  2002  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Microarray analysis of gene expression in transgenic lenses expressing dominant-negative TGF beta receptors

R De Iongh, JW McAvoy

Conference Proceedings  |  2002  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

A role for Wnt signalling in lens epithelial differentiation

JW McAvoy, R Stump, T von Bahr, S Ang, KI Pinson, RU de Iongh, FJ Lovicu

Conference Proceedings  |  2002  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Localization of the extracellular Ca2 -sensing receptor in the human placenta

RA Bradbury, J Cropley, O Kifor, FJ Lovicu, RU de Iongh, E Kable, EM Brown, EW Seely, BB Peat, AD Conigrave

Journal article  |  2002  |  Placenta

Requirement for TGF beta receptor signaling during terminal lens fiber differentiation

RU de Longh, FJ Lovicu, PA Overbeek, MD Schneider, J Joya, ED Hardeman, JW McAvoy

Journal article  |  2001  |  Development

TGF beta receptor expression in lens: Implications for differentiation and cataractogenesis

RU De Iongh, C Gordon-Thomson, CG Chamberlain, AM Hales, JW McAvoy

Journal article  |  2001  |  Experimental Eye Research

Altered integrin expression during TGF beta-induced cataract formation.

ED Wederell, FJ Lovicu, AM Hales, JW McAvoy, RU de Longh

Conference Proceedings  |  2001  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Accuracy in gamma camera measurements of point source velocities

LC Morgan, MA Pearson, DW Mackey, J Rutland, RU de Iongh, MJ Peters, H van der Wall

Journal article  |  2000  |  Nucl Med Commun.

Peter Bishop Lecture: Growth factors in lens development and cataract: key roles for fibroblast growth factor and TGF-beta

JW McAvoy, CG Chamberlain, RU de Iongh, AM Hales, FJ Lovicu

Journal article  |  2000  |  Clinical and Experimental Ophthalmology

Effect of null mutation of the fgfr3 gene on lens differentiation.

RU de Iongh, C Deng, JW McAvoy

Conference Proceedings  |  2000  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Integrin expression during lens morphogenesis and differentiation.

JW McAvoy, ED Wederell, CG Chamberlain, RU de Iongh

Conference Proceedings  |  2000  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Comparison of flutter device(FD) with postural drainage (PD) in adult patients with non-CF bronchiectasis

LC Morgan, L Maxwell, R De Longh, MJ Peters, J Rutland

Journal article  |  1999  |  Respirology

Formyl-methionyl-leucyl-phenylalanine (FMLP) does not impair ciliary beat frequency in chronic airflow limitation (CAL)

A Hansford, J Rutland, R De Longh, M Peters, B Graham, M Matheson, N Berend

Journal article  |  1999  |  Respirology

Lens development

JW McAvoy, CG Chamberlain, RU de Iongh, AM Hales, FJ Lovicu

Journal article  |  1999  |  Eye

Differential cataractogenic potency of TGF-beta(1), -beta(2), and -beta(3) and their expression in the postnatal rat eye

C Gordon-Thomson, RU de Iongh, AM Hales, CG Chamberlain, JW McAvoy

Journal article  |  1998  |  Invest Ophthalmol Vis Sci.

Diagnosis of primary ciliary dyskinesia

J Rutland, L Morgan, KA Waters, P van Asperen, RU de Iongh

Book Chapter  |  1998

Differential expression of fibroblast growth factor receptors during rat lens morphogenesis and growth

RU deIongh, FJ Lovicu, CG Chamberlain, JW McAvoy

Journal article  |  1997  |  Invest Ophthalmol Vis Sci.

Expression patterns of TGF-beta 1-3 and their relative potencies for cataractogenesis

RU deIongh, C GordonThomson, AM Hales, CG Chamberlain, JW McAvoy

Conference Proceedings  |  1997  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Expression of FGF-1 and FGF-2 mRNA during lens morphogenesis, differentiation and growth

FJ Lovicu, RU deIongh, JW McAvoy

Journal article  |  1997  |  Curr Eye Res

FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth

RU deIongh, FJ Lovicu, A Hanneken, A Baird, JW McAvoy

Journal article  |  1996  |  Developmental Dynamics

FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth

RU De Iongh, FJ Lovicu, A Hanneken, A Baird, JW Mcavoy

Journal article  |  1996  |  Developmental Dynamics

Age-related competence of TGF-beta response in rat lens epithelium correlates with receptor expression

RU deIongh, C GordonThomson, CG Chamberlain, JW McAvoy

Journal article  |  1996  |  Investigative Ophthalmology and Visual Science

CILIARY DEFECTS IN HEALTHY-SUBJECTS, BRONCHIECTASIS, AND PRIMARY CILIARY DYSKINESIA

RU DEIONGH, J RUTLAND

Journal article  |  1995  |  American Journal of Respiratory and Critical Care Medicine

SPATIOTEMPORAL DISTRIBUTION OF ACIDIC AND BASIC FGF INDICATES A ROLE FOR FGF IN RAT LENS MORPHOGENESIS

R DEIONGH, JW MCAVOY

Journal article  |  1993  |  Developmental Dynamics

ACIDIC AND BASIC FGF IN OCULAR MEDIA AND LENS - IMPLICATIONS FOR LENS POLARITY AND GROWTH-PATTERNS

MW SCHULZ, CG CHAMBERLAIN, RU DELONGH, JW MCAVOY

Journal article  |  1993  |  Development

FGF RECEPTOR EXPRESSION DURING LENS MORPHOGENESIS AND GROWTH

R DEIONGH, F LOVICU, A HANNEKEN, P MAHER, A BAIRD, JW MCAVOY

Conference Proceedings  |  1993  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Cellular localization of aFGF during early lens development by a triple fluorescent labeling technique

R de Iongh, JW McAvoy

Journal article  |  1993  |  Journal of Computer-Assisted Microscopy

SPATIOTEMPORAL EXPRESSION OF ACIDIC FIBROBLAST GROWTH-FACTOR (AFGF) INDICATES A ROLE FOR FGF IN LENS MORPHOGENESIS

R DEIONGH, JW MCAVOY

Conference Proceedings  |  1992  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

MUCOCILIARY FUNCTION, CILIARY ULTRASTRUCTURE, AND CILIARY ORIENTATION IN YOUNGS SYNDROME

R DEIONGH, A ING, J RUTLAND

Journal article  |  1992  |  Thorax

Distribution of acidic and basic fibroblast growth factors (FGF) in the foetal rat eye: implications for lens development.

R de Iongh, JW McAvoy

Journal article  |  1992  |  Growth Factors

Previously we reported that, in vitro, lens cells proliferate, migrate or differentiate in response to low, medium and high concen..

THE ROLE OF FIBROBLAST GROWTH-FACTOR IN EYE LENS DEVELOPMENT

JW MCAVOY, CG CHAMBERLAIN, RU DEIONGH, NA RICHARDSON, FJ LOVICU

Journal article  |  1991  |  Annals of the New York Academy of Sciences

IMMUNOHISTOCHEMICAL LOCALIZATION OF AFGF AND BFGF IN THE EYE OF THE 20-DAY RAT FETUS

R DEIONGH, JW MCAVOY

Conference Proceedings  |  1991  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

RANDOM CILIARY ORIENTATION - A CAUSE OF RESPIRATORY-TRACT DISEASE

J RUTLAND, RU DEIONGH

Journal article  |  1990  |  New England Journal of Medicine

A QUANTITATIVE ULTRASTRUCTURAL-STUDY OF MOTOR AND SENSORY LUMBOSACRAL NERVE ROOTS IN THE THALIDOMIDE-TREATED RABBIT FETUS

RU DEIONGH

Journal article  |  1990  |  J Neuropathol Exp Neurol.

ORIENTATION OF RESPIRATORY-TRACT CILIA IN PATIENTS WITH PRIMARY CILIARY DYSKINESIA, BRONCHIECTASIS, AND IN NORMAL SUBJECTS

R DEIONGH, J RUTLAND

Journal article  |  1989  |  Journal of Clinical Pathology

QUANTITATIVE NEUROPATHOLOGY OF THE PERIPHERAL-NERVES IN RABBIT THALIDOMIDE EMBRYOPATHY

RU DEIONGH, J MCCREDIE

Conference Proceedings  |  1987  |  TERATOLOGY

THALIDOMIDE DEFORMITIES AND THEIR NERVE SUPPLY

J MCCREDIE, K NORTH, R DEIONGH

Journal article  |  1984  |  Journal of Anatomy