Gail Risbridger

Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells

A Jaeschke, A Jacobi, MG Lawrence, GP Risbridger, M Frydenberg, ED Williams, I Vela, DW Hutmacher, LJ Bray, A Taubenberger

Journal article  |  2020  |  Materials Today Bio

Reciprocal interactions between prostate epithelial cells and their adjacent stromal microenvironment not only are essential for t..

High-Aspect-Ratio SU-8-Based Optofluidic Device for Ammonia Detection in Cell Culture Media

Esma Dervisevic, Nicolas H Voelcker, Gail Risbridger, Kellie L Tuck, Victor J Cadarso

Journal article  |  2020  |  ACS Sensors

Miniaturization of sensing technology has led to the development of multifunctional micro total analysis systems (μTAS) that benef..

Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 CD29/CD49fhi in mice

Genevieve Dall, Jessica Vieusseux, Yashar Seyed-Razavi, Nathan Godde, Mandy Ludford-Menting, Sarah M Russell, Alan Ashworth, Robin L Anderson, Gail P Risbridger, Mark Shackleton, Kara L Britt

Journal article  |  2020  |  Breast Cancer Research and Treatment

CRISP3 expression drives prostate cancer invasion and progression

Marianna Volpert, Luc Furic, Jinghua Hu, Anne E O'Connor, Richard J Rebello, Shivakumar Keerthikumar, Jemma Evans, D Jo Merriner, John Pedersen, Gail P Risbridger, Peter McIntyre, Moira K O'Bryan

Journal article  |  2020  |  Endocrine Related Cancer

Identifying the factors stimulating prostate cancer cells migration and invasion has the potential to bring new therapeutic target..

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

Dilys Lam, Phuc-Loi Luu, Jenny Z Song, Wenjia Qu, Gail P Risbridger, Mitchell G Lawrence, Jennifer Lu, Matt Trau, Darren Korbie, Susan J Clark, Ruth Pidsley, Clare Stirzaker

Journal article  |  2020  |  Clinical Epigenetics

BACKGROUND: DNA methylation is a well-studied epigenetic mark that is frequently altered in diseases such as cancer, where specifi..

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

Michael D Nyquist, Alexandra Corella, Ilsa Coleman, Navonil De Sarkar, Arja Kaipainen, Gavin Ha, Roman Gulati, Lisa Ang, Payel Chatterjee, Jared Lucas, Colin Pritchard, Gail Risbridger, John Isaacs, Bruce Montgomery, Colm Morrissey, Eva Corey, Peter S Nelson

Journal article  |  2020  |  Cell Reports

Prostate cancers (PCs) with loss of the potent tumor suppressors TP53 and RB1 exhibit poor outcomes. TP53 and RB1 also influence c..

Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

Mitchell G Lawrence, Ruth Pidsley, Birunthi Niranjan, Melissa Papargiris, Brooke A Pereira, Michelle Richards, Linda Teng, Sam Norden, Andrew Ryan, Mark Frydenberg, Clare Stirzaker, Renea A Taylor, Gail P Risbridger, Susan J Clark

Journal article  |  2020  |  Clinical Epigenetics

BACKGROUND: Prostate cancer changes the phenotype of cells within the stromal microenvironment, including fibroblasts, which in tu..

Knowing what's growing: Why ductal and intraductal prostate cancer matter

Mitchell G Lawrence, Laura H Porter, David Clouston, Declan G Murphy, Mark Frydenberg, Renea A Taylor, Gail P Risbridger

Journal article  |  2020  |  Science Translational Medicine

New patient-derived models of castrate-sensitive and castrate-resistant prostate cancer

Mitchell Lawrence, David Clouston, Mark Frydenberg, Declan G Murphy, Carmel Jo Pezaro, David William Pook, Heather Thorne, Shahneen Kaur Sandhu, Roxanne Toivanen, Renea Taylor, Gail Risbridger

Conference Proceedings  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY

New patient-derived models of castrate-sensitive and castrate-resistant prostate cancer.

Mitchell Lawrence, David Clouston, Mark Frydenberg, Declan G Murphy, Carmel Jo Pezaro, David William Pook, Heather Thorne, Shahneen Kaur Sandhu, Roxanne Toivanen, Renea Taylor, Gail Risbridger

Conference Proceedings  |  2020  |  Journal of Clinical Oncology

151 Background: There are fewer preclinical models of prostate cancer compared to other common tumours. New models that represent..