Lucy Sullivan

Cytomegalovirus replication is associated with enrichment of distinct γδ T cell subsets following lung transplantation: A novel therapeutic approach?

Sanda Stankovic, Martin S Davey, Evangeline M Shaw, Anouk von Borstel, Yvonne Cristiano, Bronwyn J Levvey, Jamie Rossjohn, Glen P Westall, Gregory I Snell, Andrew G Brooks, Lucy C Sullivan

Journal article  |  2020  |  The Journal of Heart and Lung Transplantation

BACKGROUND: Anti-viral treatments to control cytomegalovirus (CMV) after lung transplantation (LTx) are associated with toxicity a..

Harnessing HLA-E-restricted CD8 T lymphocytes for adoptive cell therapy of patients with severe COVID-19

Nadia Caccamo, Lucy C Sullivan, Andrew G Brooks, Francesco Dieli

Journal article  |  2020  |  British Journal of Haematology

SARS-CoV-2 is spreading worldwide, and is a pandemic virus that has infected almost 5 million individuals and causing 300.000 deat..

Natural Killer (NK) Cells: The Missing Link between Antibody-Mediated Rejection (ABMR) and Chronic Lung Allograft Dysfunction (CLAD)?

CM Fernandes Monteiro, DC Walton, Y Cristiano, BJ Levvey, GI Snell, GP Westall, AG Brooks, LC Sullivan

Conference Proceedings  |  2020  |  The Journal of Heart and Lung Transplantation

A Potential Role for NKG2C gamma delta T Cells as a Cellular Therapy in Combating Post-Lung Transplant Cytomegalovirus Infection

S Stankovic, MS Davey, EM Shaw, Y Cristiano, GI Snell, GP Westall, AG Brooks, LC Sullivan

Conference Proceedings  |  2020  |  The Journal of Heart and Lung Transplantation

HLA Epitope Mismatch Load (epMM) Allows Classification of Immunological Risk and Correlates with Patient Survival Following Lung Transplantation (LTx)

SJ Hiho, MA Paraskeva, DC Walton, MB Diviney, BJ Levvey, GI Snell, LC Sullivan, GP Westall

Conference Proceedings  |  2020  |  The Journal of Heart and Lung Transplantation

HLA-E-restricted CD8( ) T Lymphocytes Efficiently Control Mycobacterium tuberculosis and HIV-1 Coinfection

Marco Pio La Manna, Valentina Orlando, Teresa Prezzemolo, Paola Di Carlo, Antonio Cascio, Giovanni Delogu, Guido Poli, Lucy C Sullivan, Andrew G Brooks, Francesco Dieli, Nadia Caccamo

Journal article  |  2020  |  American Journal of Respiratory Cell and Molecular Biology

We investigated the contribution of human leukocyte antigen A2 (HLA-A2) and HLA-E-restricted CD8+ T cells in patients with Mycobac..

Can Avoiding So-Called HLA High Risk Epitope Mismatches (REM) Improve Lung Transplant (LTx) Outcomes?

SJ Hiho, MA Paraskeva, DC Walton, MB Diviney, BJ Levvey, GI Snell, LC Sullivan, GP Westall

Conference Proceedings  |  2020  |  The Journal of Heart and Lung Transplantation

The murine CD94/NKG2 ligand, Qa-1(b), is a high-affinity, functional ligand for the CD8?? homodimer

Katharine Jennifer Goodall, Angela Nguyen, Craig McKenzie, Sidonia Barbara Guiomar Eckle, Lucy Catherine Sullivan, Daniel Mark Andrews

Journal article  |  2020  |  Journal of Biological Chemistry

The immune co-receptor CD8 molecule (CD8) has two subunits, CD8α and CD8β, which can assemble into homo or heterodimers. Nonclassi..

Consequences of donor-derived passengers (pathogens, cells, biological molecules and proteins) on clinical outcomes

Gregory Snell, Steven Hiho, Bronwyn Levvey, Lucy Sullivan, Glen Westall

Journal article  |  2019  |  The Journal of Heart and Lung Transplantation

Enrichment of Cytomegalovirus-induced NKG2C( ) Natural Killer Cells in the Lung Allograft

Christopher M Harpur, Sanda Stankovic, Abbie Kanagarajah, Jacqueline ML Widjaja, Bronwyn J Levvey, Yvonne Cristiano, Greg I Snell, Andrew G Brooks, Glen P Westall, Lucy C Sullivan

Journal article  |  2019  |  Transplantation

BACKGROUND: In lung transplant recipients, immunosuppressive medications result in impaired antiviral immunity and a propensity fo..