Linda Earnest

HBV-related hepatocarcinogenesis: the role of signalling pathways and innovative ex vivo research models

Joseph Torresi, Manh Tran Bang, Dale Christiansen, Linda Earnest-Silveira, Renate Hilda Marianne Schwab, Elizabeth Vincan

Journal article  |  2019  |  BMC Cancer

BACKGROUND: Hepatitis B virus (HBV) is the leading cause of liver cancer, but the mechanisms by which HBV causes liver cancer are ..

Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery

D Christiansen, L Earnest-Silveira, B Grubor-Bauk, DK Wijesundara, I Boo, PA Ramsland, E Vincan, HE Drummer, EJ Gowans, J Torresi

Journal article  |  2019  |  Scientific Reports

Probing and pressing surfaces of hepatitis C virus-like particles

Simon Collett, Joseph Torresi, Linda Earnest-Silveira, Dale Christiansen, Aaron Elbourne, Paul A Ramsland

Journal article  |  2019  |  Journal of Colloid and Interface Science

A Hepatitis C Virus DNA Vaccine Encoding a Secreted, Oligomerized Form of Envelope Proteins Is Highly Immunogenic and Elicits Neutralizing Antibodies in Vaccinated Mice

Makutiro Ghislain Masavuli, Danushka K Wijesundara, Alexander Underwood, Dale Christiansen, Linda Earnest-Silveira, Rowena Bull, Joseph Torresi, Eric J Gowans, Branka Grubor-Bauk

Journal article  |  2019  |  Frontiers in Immunology

Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine

D Christiansen, L Earnest-Silveira, B Chua, P Meuleman, I Boo, B Grubor-Bauk, DC Jackson, ZY Keck, SKH Foung, HE Drummer, EJ Gowans, J Torresi

Journal article  |  2018  |  Scientific Reports

Antibody Responses to a Quadrivalent Hepatitis C Viral-Like Particle Vaccine Adjuvanted with Toll-Like Receptor 2 Agonists

Dale Christiansen, Linda Earnest-Silveira, Brendon Chua, Irene Boo, Heidi E Drummer, Branka Grubor-Bauk, Eric J Gowans, David C Jackson, Joseph Torresi

Journal article  |  2018  |  Viral Immunology

Large scale production of a mammalian cell derived quadrivalent hepatitis C virus like particle vaccine

L Earnest-Silveira, D Christiansen, S Herrmann, SA Ralph, S Das, EJ Gowans, J Torresi

Journal article  |  2016  |  Journal of Virological Methods

Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line

L Earnest-Silveira, B Chua, R Chin, D Christiansen, D Johnson, S Herrmann, SA Ralph, K Vercauteren, A Mesalam, P Meuleman, S Das, I Boo, H Drummer, C-T Bock, EJ Gowans, DC Jackson, Joseph Torresi

Journal article  |  2016  |  Journal of General Virology

Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis

Eu Jin Lim, Korri El Khobar, Ruth Chin, Linda Earnest-Silveira, Peter W Angus, C-Thomas Bock, Ueli Nachbur, John Silke, Joseph Torresi

Journal article  |  2014  |  Journal of General Virology

The Incidence of HBV and HCV Infection in Australian Travelers to Asia

Douglas F Johnson, Irani Ratnam, Elizabeth Matchett, Linda Earnest-Silveria, Dale Christiansen, Karin Leder, Michael L Grayson, Joseph Torresi

Journal article  |  2013  |  Journal of Travel Medicine

HEPATITIS C VLPS DELIVERED TO DENDRITIC CELLS BY A TLR2 TARGETING LIPOPEPTIDE RESULTS IN ENHANCED NEUTRALIZING ANTIBODY AND CELL-MEDIATED RESPONSES

J Torresi, R Chin, B Chua, D Johnson, L Earnest-Sliveira, W Zeng, E Gowans, TC Bock, DC Jackson

Conference Proceedings  |  2013  |  Journal of Hepatology

Impaired dendritic cell maturation in response to pandemic H1N109 influenza virus

Ruth Chin, Linda Earnest-Silviera, Claire L Gordon, Karen Olsen, Ian Barr, Lorena E Brown, David C Jackson, Joseph Torresi

Journal article  |  2013  |  Journal of Clinical Virology

Hepatitis C VLPs Delivered to Dendritic Cells by a TLR2 Targeting Lipopeptide Results in Enhanced Antibody and Cell-Mediated Responses

Brendon Y Chua, Douglas Johnson, Amabel Tan, Linda Earnest-Silveira, Toshiki Sekiya, Ruth Chin, Joseph Torresi, David C Jackson

Journal article  |  2012  |  PLOS ONE

Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus

Ruth Chin, Ulrich Nachbur, Linda Earnest-Silveira, Aleksandra Bankovacki, Bernd Koeberlein, Hanswalter Zentgraf, C-Thomas Bock, John Silke, Joseph Torresi

Journal article  |  2010  |  Virus Research

Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response

Duangtawan Thammanichanond, Sarah Moneer, Patricia Yotnda, Campbell Aitken, Linda Earnest-Silveira, David Jackson, Margaret Hellard, James McCluskey, Joseph Torresi, Mandvi Bharadwaj

Journal article  |  2008  |  Clinical Immunology

Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: Factors contributing to hepatocarcinogenesis

Ruth Chin, Linda Earnest-Silveira, Bernd Koeberlein, Susanne Franz, Hanswalter Zentgraf, Xuebin Dong, Eric Gowans, C-Thomas Bock, Joseph Torresi

Journal article  |  2007  |  Hepatology

A self-adjuvanting multiepitope immunogen that induces a broadly cross-reactive antibody to hepatitis C virus

Joseph Torresi, Owen M Stock, Alexandra E Fischer, Lara Grollo, Heidi Drummer, Irene Boo, Weiguang Zeng, Linda Earnest-Silveira, David C Jackson

Journal article  |  2007  |  Hepatology

Severe hepatitis and prolonged hepatitis B virus-specific CD8 T-cell response after selection of hepatitis B virus YMDD variant in an HIV/hepatitis B virus-co-infected patient

T Gouskos, F Wightman, J Chang, L Earnest-Silveira, J Sasadeusz, SR Lewis, J Torresi

Journal article  |  2004  |  AIDS