Stephen Tong

DAAM2 is elevated in the circulation and placenta in pregnancies complicated by fetal growth restriction and is regulated by hypoxia.

Natasha de Alwis, Sally Beard, Natalie K Binder, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Owen Stock, Katie Groom, Scott Petersen, Amanda Henry, Joanne M Said, Sean Seeho, Stefan C Kane, Lisa Hui, Stephen Tong, Natalie J Hannan

Journal article  |  2021  |  Scientific Reports

Previously, we identified increased maternal circulating DAAM2 mRNA in pregnancies complicated by preterm fetal growth restriction..

Aspirin to prevent pre-eclampsia.

Stephen Tong, Susan Walker, Catherine Cluver, Roxanne Hastie

Journal article  |  2021  |  Drug and Therapeutics Bulletin

Topics for DTB review articles are selected by DTB's editorial board to provide concise overviews of medicines and other treatment..

Nanoparticles in pregnancy: the next frontier in reproductive therapeutics.

Natasha Pritchard, Tu'uhevaha Kaitu'u-Lino, Lynda Harris, Stephen Tong, Natalie Hannan

Journal article  |  2021  |  Human Reproduction Update

BACKGROUND: Nanotechnology involves the engineering of structures on a molecular level. Nanomedicine and nano-delivery systems hav..

27 Metformin to treat Preterm Pre-eclampsia (PI-2): A randomised, double blind, placebo-controlled trial

Catherine Anne Cluver, Richard Hiscock, Eric H Decloedt, David R Hall, Sonja Schell, Ben Mol, Fiona Brownfoot, Tu'uhevaha Kaitu' u-Lino, Susan Walker, Stephen Tong

Journal article  |  2021  |  American Journal of Obstetrics and Gynecology

Circulating Tissue Factor Pathway Inhibitor (TFPI) is increased preceding preeclampsia diagnosis and in established preeclampsia

Teresa M MacDonald, Stephen Tong, Jenny Myers, Ping Cannon, Nguyen Tuong-Vi, Emerson Keenan, Elizabeth Murray, Alesia Harper, Natasha Pritchard, Natalie J Hannan, Kirsten M Dane, Anna L Middleton, Valerie P Kyritsis, Susan P Walker, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2021  |  Placenta

INTRODUCTION: Tissue Factor Pathway Inhibitor (TFPI) is a part of the extrinsic coagulation pathway, and highly expressed in the p..

Measuring circulating miRNAs in early pregnancy could identify fetuses' destined to undergrow and be at increased risk of stillbirth.

Stephen Tong, Tu'uhevaha Kaitu'u-Lino

Journal article  |  2021  |  EBioMedicine

Aspirin use during pregnancy and the risk of bleeding complications: a Swedish population-based cohort study

Roxanne Hastie, Stephen Tong, Anna-Karin Wikstrom, Anna Sandstrom, Susanne Hesselman, Lina Bergman

Journal article  |  2021  |  American Journal of Obstetrics and Gynecology

BACKGROUND: Aspirin is offered to pregnant women to prevent preeclampsia, a severe obstetrical complication. Large studies of nonp..

Reduced growth velocity from the mid-trimester is associated with placental insufficiency in fetuses born at a normal birthweight.

Lucy M Kennedy, Stephen Tong, Alice J Robinson, Richard J Hiscock, Lisa Hui, Kirsten M Dane, Anna L Middleton, Susan P Walker, Teresa M MacDonald

Journal article  |  2020  |  BMC Medicine

BACKGROUND: Fetal growth restriction (FGR) due to placental insufficiency is a major risk factor for stillbirth. While small-for-g..

Preventable stillbirths in the Solomon Islands – A hidden tragedy

Manarangi De Silva, Leeanne Panisi, Lenin Manubuasa, Catherine Honimae, Susan Taragwanu, Simon Burggraaf, Divinal Ogaoga, Anthea Lindquist, Susan Walker, Stephen Tong, Roxanne Hastie

Journal article  |  2020  |  The Lancet Regional Health - Western Pacific

Novel approaches to combat preeclampsia: from new drugs to innovative delivery

Natasha de Alwis, Natalie K Binder, Sally Beard, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong, Fiona Brownfoot, Natalie J Hannan

Journal article  |  2020  |  Placenta

Preeclampsia is a complex disease affecting 2-8% of pregnancies worldwide. It poses significant risk of maternal and perinatal mor..