David Gyorki

ASO Author Reflections: The Impacts of a Negative Sentinel Lymph Node on Quality of Life

Sarah Banting, David E Gyorki

Journal article  |  2019  |  Annals of Surgical Oncology

Inguinal and Ilio-inguinal Lymphadenectomy in Management of Palpable Melanoma Lymph Node Metastasis: A Long-Term Prospective Evaluation of Morbidity and Quality of Life

Michael A Henderson, D Gyorki, BH Burmeister, J Ainslie, R Fisher, J Di Iulio, BM Smithers, A Hong, K Shannon, RA Scolyer, S Carruthers, BJ Coventry, S Babington, J Duprat, HJ Hoekstra, JF Thompson

Journal article  |  2019  |  Annals of Surgical Oncology

PURPOSE: Prospective data are lacking on long-term morbidity of inguinal lymphadenectomy including the influence of extent of surg..

The Prognosis and Natural History of In-Transit Melanoma Metastases at a High-Volume Centre

Emilia Nan Tie, Lumine H Na, Rodney J Hicks, John Spillane, David Speakman, Michael A Henderson, David E Gyorki

Journal article  |  2019  |  Annals of Surgical Oncology

BACKGROUND: Patients with in-transit melanoma metastases (ITM) experience a diverse spectrum of clinical presentations and a highl..

Skin colonization with beta papilloma virus drives tissue immunity and resistance to squamous cell cancer

Katharina Hochheiser, David E Gyorki, Thomas Gebhardt

Journal article  |  2019  |  Immunology & Cell Biology

Intercontinental collaborative experience with abdominal, retroperitoneal and pelvic schwannomas.

undefined Transatlantic Australasian Retroperitoneal Sarcoma Working Group

Journal article  |  2019  |  British Journal of Surgery

BACKGROUND: Schwannomas are rare tumours that pose a significant management challenge in the abdomen, retroperitoneum and pelvis. ..

Locoregional melanoma: identifying optimal care in a rapidly changing landscape

David E Gyorki, Jonathan S Zager

Journal article  |  2019  |  Melanoma Management

A randomised, double-blind, placebo-controlled, multi-institutional phase II study of adjuvant anti-PD-1 in patients with stage I-III Merkel cell carcinoma [I-MAT study]

Wen Xu, Michael Poulsen, Victoria Atkinson, Gerald Fogarty, Michael Veness, Bernard Smithers, David Gyorki, Victoria Mar, Julie Howle, Alexander Guminski, Narelle Williams, Elizabeth Paton

Conference Proceedings  |  2019  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Systemic therapies for unresectable locoregional melanoma: a significant area of need

Emilia Nan Tie, Julia E Lai-Kwon, David E Gyorki

Journal article  |  2019  |  Melanoma Management

Immune checkpoint inhibitors and BRAF-MEK inhibitors have revolutionized the management and prognosis of patients with metastatic ..

An evidence-based approach to positive sentinel node disease: should we ever do a completion node dissection?

Jennifer S Downs, David E Gyorki

Journal article  |  2019  |  Melanoma Management

Management of later stage melanoma has undergone significant changes. Sentinel node biopsy has long been an accepted method of sta..

Characterizing high-grade serous papillary carcinoma of tunica vaginalis

Liang G Qu, Jiasian Teh, Catherine Mitchell, David E Gyorki, Rodney J Hicks, Declan G Murphy

Journal article  |  2019  |  Urology Case Reports

Serous carcinomas of the testis or para-testis are extremely rare tumors of Mullerian type. We report a case of high-grade serous ..

Management of in-transit melanoma metastases: a review

Emilia Nan Tie, Michael A Henderson, David E Gyorki

Journal article  |  2019  |  ANZ Journal of Surgery

Efficacy of immune checkpoint inhibitors (ICIs) for in-transit melanoma.

Emilia Nan Tie, Julia Elizabeth Lai-Kwon, Lumine Na, Michael Alexander Rtshiladze, James Bozzi, Tavis Read, Victoria Atkinson, George Au-Yeung, Georgina V Long, Grant A McArthur, Shahneen Kaur Sandhu, Robyn Saw, Euan Thomas Walpole, Alexander M Menzies, B Mark Smithers, David E Gyorki

Conference Proceedings  |  2019  |  JOURNAL OF CLINICAL ONCOLOGY

One-year (yr) recurrence-free survival (RFS) from a randomized, open label phase II study of neoadjuvant (neo) talimogene laherparepvec (T-VEC) plus surgery (surgx) versus surgx for resectable stage IIIB-IVM1a melanoma (MEL).

Reinhard Dummer, David E Gyorki, John Robert Hyngstrom, Adam C Berger, Robert Martin Conry, Lev V Demidov, Anjali Sharma, Sheryl Treichel, Mark B Faries, Merrick I Ross

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA

L Tan, S Sandhu, RJ Lee, J Li, J Callahan, S Ftouni, N Dhomen, P Middlehurst, A Wallace, J Raleigh, A Hatzimihalis, MA Henderson, M Shackleton, A Haydon, V Mar, DE Gyorki, D Oudit, MA Dawson, RJ Hicks, P Lorigan, et al.

Journal article  |  2019  |  Annals of Oncology

BACKGROUND: The advent of effective adjuvant therapies for patients with resected melanoma has highlighted the need to stratify pa..

The Role of FDG - PET in Retroperitoneal Sarcomas - A Multicenter Retrospective Study

S Subramaniam, J Callahan, M Bressel, M Hofman, C Mitchell, S Hendry, FL Vissers, B van der Hiel, D Patel, WJ van Houdt, W Tseng, DE Gyorki

Conference Proceedings  |  2019  |  ANNALS OF SURGICAL ONCOLOGY

Predictors of Acute Surgical Complications Following Wide Local Excision and Sentinel Lymph Node Biopsy for Melanoma - Analysis from a Prospective Clinical Trial

DE Gyorki, M Moncrieff, R Saw, A Spillane, J Thompson, H Peach, D Oudit, J Geh, P Dziewulski, E Wilson, P Matteucci, R Pritchard-Jones, R Olofsson Bagge, F Wright, N Crampton, O Cassell, N Jallali, AC Berger, J Kelly, S Hamilton, et al.

Conference Proceedings  |  2019  |  ANNALS OF SURGICAL ONCOLOGY

Tissue-resident memory CD8( ) T cells promote melanoma-immune equilibrium in skin

Simone L Park, Anthony Buzzai, Jai Rautela, Jyh Liang Hor, Katharina Hochheiser, Maike Effern, Nathan McBain, Teagan Wagner, Jarem Edwards, Robyn McConville, James S Wilmott, Richard A Scolyer, Thomas Tueting, Umaimainthan Palendria, David Gyorki, Scott N Mueller, Nicholas D Huntington, Sammy Bedoui, Michael Hoelzel, Laura K Mackay, et al.

Journal article  |  2019  |  Nature

Accumulation of CD103( ) CD8( ) T cells in a cutaneous melanoma micrometastasis

Katharina Hochheiser, Han Xian Aw Yeang, Teagan Wagner, Candani Tutuka, Andreas Behren, Jason Waithman, Christopher Angel, Paul J Neeson, Thomas Gebhardt, David E Gyorki

Journal article  |  2019  |  Clinical & Translational Immunology

Objective: The immune system can halt cancer progression by suppressing outgrowth of clinically occult micrometastases in a state ..

Ectopic breast cancer in the inguinal region

Zoe Loh, Belinda Yeo, David S Williams, David E Gyorki

Journal article  |  2019  |  The Breast Journal

Neutrophil to lymphocyte ratio is an independent predictor of outcome for patients undergoing definitive resection for stage IV melanoma

Stefanos Kanatsios, Melbourne Melanoma Project, Connie SN Li Wai Suen, Jonathan Simon Cebon, David E Gyorki

Journal article  |  2018  |  Journal of Surgical Oncology

Treatment of patients with primary retroperitoneal sarcoma: predictors of outcome from an Australian specialist sarcoma centre

Hayden A Snow, Tatiana X Hitchen, Jessica Head, Alan Herschtal, Susie Bae, Sarat Chander, Julie Chu, Shona Hendry, Samuel Y Ngan, Jayesh Desai, Peter FM Choong, Michael Henderson, David E Gyorki

Journal article  |  2018  |  ANZ Journal of Surgery

Circulating tumour DNA analysis predicts relapse following resection in stage II and III melanoma

L Tan, SK Sandhu, R Lee, J Li, J Callahan, J Raleigh, A Hatzimihalis, P Middlehurst, M Henderson, M Shackleton, A Haydon, D Gyorki, D Oudit, RJ Hicks, P Lorigan, GA McArthur, R Marais, SQ Wong, S-J Dawson

Conference Proceedings  |  2018  |  ANNALS OF ONCOLOGY

1 Versus 2-cm Excision Margins for pT2-pT4 Primary Cutaneous Melanoma (MelMarT): A Feasibility Study

Marc D Moncrieff, David Gyorki, Robyn Saw, Andrew J Spillane, Howard Peach, Deemesh Oudit, Jenny Geh, Peter Dziewulski, Ewan Wilson, Paolo Matteucci, Rowan Pritchard-Jones, Roger Olofsson Bagge, Frances C Wright, Nic Crampton, Oliver Cassell, Navid Jallali, Adam Berger, John Kelly, Stephen Hamilton, Amer Durrani, et al.

Journal article  |  2018  |  Annals of Surgical Oncology

Melanoma in the very elderly, management in patients 85 years of age and over

Matthew J Rees, Henry Liao, John Spillane, David Speakman, Chris McCormack, Simon Donahoe, Miki Pohl, Angela Webb, David Gyorki, Michael A Henderson

Journal article  |  2018  |  Journal of Geriatric Oncology

Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

H Halse, AJ Colebatch, P Petrone, MA Henderson, JK Mills, H Snow, JA Westwood, S Sandhu, JM Raleigh, A Behren, J Cebon, PK Darcy, MH Kershaw, GA McArthur, DE Gyorki, PJ Neeson

Journal article  |  2018  |  Scientific Reports

Surveillance imaging with FDG-PET/CT in the post-operative follow-up of stage 3 melanoma

J Lewin, L Sayers, D Kee, I Walpole, A Sanelli, L te Marvelde, A Herschtal, J Spillane, D Gyorki, D Speakman, V Estall, S Donahoe, M Pohl, K Pope, M Chua, S Sandhu, GA McArthur, CJ McCormack, M Henderson, RJ Hicks, et al.

Journal article  |  2018  |  Annals of Oncology

Incidental Metastatic Melanoma Identified on 68Ga-Prostate-Specific Membrane Antigen PET/CT for Metastatic Prostate Cancer

Hayden A Snow, Michael S Hofman, Catherine A Mitchell, David E Gyorki, Myles JF Smith

Journal article  |  2018  |  Clinical Nuclear Medicine

Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

Peter Savas, Balaji Virassamy, Chengzhong Ye, Agus Salim, Christopher P Mintoff, Franco Caramia, Roberto Salgado, David J Byrne, Zhi L Teo, Sathana Dushyanthen, Ann Byrne, Lironne Wein, Stephen J Luen, Catherine Poliness, Sophie S Nightingale, Anita S Skandarajah, David E Gyorki, Chantel M Thornton, Paul A Beavis, Stephen B Fox, et al.

Journal article  |  2018  |  Nature Medicine

Adoptive cell therapy for melanoma

J Mills, P Darcy, DE Gyorki

Book Chapter  |  2018

Systematic Review of Clinical Outcomes Following Various Treatment Options for Patients with Extraabdominal Desmoid Tumors

Kortnye Smith, Jayesh Desai, Smaro Lazarakis, David Gyorki

Journal article  |  2018  |  Annals of Surgical Oncology

Management of In-Transit Melanoma: We Need Some High-Quality Data

David E Gyorki

Journal article  |  2018  |  Journal of Oncology Practice

Importance of preoperative diagnosis for management of patients with suspected retroperitoneal sarcoma

David E Gyorki, Peter FM Choong, John Slavin, Michael A Henderson

Journal article  |  2018  |  ANZ Journal of Surgery

Restricted venous access after lymph node dissection: no evidence (voodoo)

Hayden Snow, Bernhard Riedel, David Gyorki, Michael A Henderson, David Speakman

Journal article  |  2018  |  ANZ Journal of Surgery

Preoperative Positron Emission Tomography for Node-Positive Head and Neck Cutaneous Squamous Cell Carcinoma

Nir Hirshoren, Elizabeth Olayos, Alan Herschtal, Aravind S Ravi Kumar, David E Gyorki

Journal article  |  2018  |  Otolaryngology–Head and Neck Surgery

Subungual melanoma: Management in the modern era

DJ Reilly, G Aksakal, RF Gilmour, DE Gyorki, A Chauhan, A Webb, MA Henderson

Journal article  |  2017  |  Journal of Plastic, Reconstructive & Aesthetic Surgery

When is a sentinel node biopsy indicated for patients with primary melanoma? An update of the 'Australian guidelines for the management of cutaneous melanoma'

David E Gyorki, Andrew Barbour, Mark Hanikeri, Victoria Mar, Shahneen Sandhu, John F Thompson

Journal article  |  2017  |  Australasian Journal of Dermatology

Surgical referral coordination from a first-level hospital: a prospective case study from rural Nepal

Matthew Fleming, Caroline King, Sindhya Rajeev, Ashma Baruwal, Dan Schwarz, Ryan Schwarz, Nirajan Khadka, Sami Pande, Sumesh Khanal, Bibhav Acharya, Adia Benton, Selwyn O Rogers, Maria Panizales, David Gyorki, Heather McGee, David Shaye, Duncan Maru

Journal article  |  2017  |  BMC Health Services Research

Prognostic markers in metastatic cutaneous squamous cell carcinoma of the head and neck

Nir Hirshoren, Julia Danne, Benjamin John Dixon, Matthew Magarey, Stephen Kleid, Angela Webb, Albert Tiong, June Corry, David Gyorki

Journal article  |  2017  |  Head & Neck

Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

Paul A Beavis, Melissa A Henderson, Lauren Giuffrida, Jane K Mills, Kevin Sek, Ryan S Cross, Alexander J Davenport, Liza B John, Sherly Mardiana, Clare Y Slaney, Ricky W Johnstone, Joseph A Trapani, John Stagg, Sherene Loi, Lev Kats, David Gyorki, Michael H Kershaw, Phillip K Darcy

Journal article  |  2017  |  Journal of Clinical Investigation

Prospective evaluation of prognostic indicators for early recurrence of cutaneous melanoma

Julia AH Matheson, Luc te Marvelde, Sonia Mailer, David Speakman, John Spillane, Michael A Henderson, David E Gyorki

Journal article  |  2017  |  Melanoma Research

Circulating Tumor DNA Analysis and Functional Imaging Provide Complementary Approaches for Comprehensive Disease Monitoring in Metastatic Melanoma

Stephen Q Wong, Jeanette M Raleigh, Jason Callahan, Ismael A Vergara, Sarah Ftouni, Athena Hatzimihalis, Andrew J Colebatch, Jason Li, Timothy Semple, Kenneth Doig, Christopher Mintoff, Devbarna Sinha, Paul Yeh, Maria Joao Silva, Kathryn Alsop, Heather Thorne, David D Bowtell, David E Gyorki, Gisela Mir Arnau, Carleen Cullinane, et al.

Journal article  |  2017  |  JCO Precision Oncology

A community-based model of rapid autopsy in end-stage cancer patients

Kathryn Alsop, Heather Thorne, Shahneen Sandhu, Anne Hamilton, Christopher Mintoff, Elizabeth Christie, Odette Spruyt, Scott Williams, Orla McNally, Linda Mileshkin, Sumitra Ananda, Julene Hallo, Sherene Loi, Clare Scott, Peter Savas, Lisa Devereux, Patricia O'Brien, Sameera Gunawardena, Clare Hampson, Kate Strachan, et al.

Journal article  |  2016  |  Nature Biotechnology

Excision margins and sentinel lymph node status as prognostic factors in thick melanoma of the head and neck: A retrospective analysis

Olivia Ruskin, Alexandra Sanelli, Alan Herschtal, Angela Webb, Ben Dixon, Miklos Pohl, Simon Donahoe, John Spillane, Michael A Henderson, David E Gyorki

Journal article  |  2016  |  Head & Neck

Localized melanoma in older patients, the impact of increasing age and comorbid medical conditions

MJ Rees, H Liao, J Spillane, D Speakman, C McCormack, S Donahoe, M Pohl, A Webb, D Gyorki, MA Henderson

Journal article  |  2016  |  European Journal of Surgical Oncology (EJSO)

Intralesional PV-10 for in-transit melanomaA single-center experience

Jocelyn Lippey, Rhiannon Bousounis, Cori Behrenbruch, Bartholomew McKay, John Spillane, Michael A Henderson, David Speakman, David E Gyorki

Journal article  |  2016  |  Journal of Surgical Oncology

CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity

Samantha E Boyle, Clare G Fedele, Vincent Corbin, Elisha Wybacz, Pacman Szeto, Jeremy Lewin, Richard J Young, Annie Wong, Robert Fuller, John Spillane, David Speakman, Simon Donahoe, Miklos Pohl, David Gyorki, Michael A Henderson, Ricky W Johnstone, Anthony T Papenfuss, Mark Shackleton

Journal article  |  2016  |  Cancer Research

A prospective study comparing digital breast tomosynthesis with digital mammography in surveillance after breast cancer treatment

Joseph Sia, Kate Moodie, Mathias Bressel, Eddie Lau, David Gyorki, Anita Skandarajah, Boon Chua

Journal article  |  2016  |  European Journal of Cancer

Recent Insights and Advances in the Management of Merkel Cell Carcinoma

Patricia D Banks, Shahneen Sandhu, David E Gyorki, Meredith L Johnston, Danny Rischin

Journal article  |  2016  |  Journal of Oncology Practice

Reprogramming the tumor microenvironment to enhance adoptive cellular therapy

Paul A Beavis, Clare Y Slaney, Michael H Kershaw, David Gyorki, Paul J Neeson, Phillip K Darcy

Journal article  |  2016  |  Seminars in Immunology

Sentinel Lymph Node Biopsy in T4 Melanoma: An Important Risk-Stratification Tool

David E Gyorki, Alexandra Sanelli, Alan Herschtal, Smaro Lazarakis, Grant A McArthur, David Speakman, John Spillane, Michael A Henderson

Journal article  |  2016  |  Annals of Surgical Oncology

Sentinel node biopsy in patients with intermediate and thick melanomas - A balanced view

Robyn Saw, Christopher Allan, Andrew Barbour, Sydney Ch'ng, Brendon J Coventry, David Gyorki, Michael Henderson, Julie Howle, T Michael Hughes, Kenneth Lee, Susan Neuhaus, Christobel Saunders, Kerwin Shannon, Mark Smithers, David Speakman, John Spillane, Jonathan Stretch

Journal article  |  2015  |  Australian Family Physician

Post-operative survival following metastasectomy for patients receiving BRAF inhibitor therapy is associated with duration of pre-operative treatment and elective indication

Mike He, Jane Lovell, Bee Ling Ng, John Spillane, David Speakman, Michael A Henderson, Mark Shackleton, David E Gyorki

Journal article  |  2015  |  Journal of Surgical Oncology

Sentinel lymph node biopsy for melanoma: an important risk-stratification tool REPLY

David E Gyorki, Michael A Henderson

Journal article  |  2015  |  Medical Journal of Australia

Sentinel lymph node biopsy for melanoma: an important risk-stratification tool

David E Gyorki, Michael A Henderson

Journal article  |  2014  |  The Medical Journal of Australia

Current management of advanced melanoma: a transformed landscape

David E Gyorki, John Spillane, David Speakman, Mark Shackleton, Michael A Henderson

Journal article  |  2014  |  ANZ Journal of Surgery

Incidence and location of positive nonsentinel lymph nodes in head and neck melanoma

DE Gyorki, JO Boyle, I Ganly, L Morris, AR Shaha, B Singh, RJ Wong, JP Shah, K Busam, D Kraus, DG Coit, S Patel

Journal article  |  2014  |  European Journal of Surgical Oncology (EJSO)

Improving the impact of didactic resident training with online spaced education

David E Gyorki, Tim Shaw, James Nicholson, Caroline Baker, Meron Pitcher, Anita Skandarajah, Eva Segelov, G Bruce Mann

Journal article  |  2013  |  ANZ Journal of Surgery

Spontaneous bacterial peritonitis: a rare mimic of acute appendicitis

Eliza R Preece, Eugene Athan, David AK Watters, David E Gyorki

Journal article  |  2012  |  ANZ Journal of Surgery

Gata-3 Negatively Regulates the Tumor-Initiating Capacity of Mammary Luminal Progenitor Cells and Targets the Putative Tumor Suppressor Caspase-14

Marie-Liesse Asselin-Labat, Kate D Sutherland, Francois Vaillant, David E Gyorki, Di Wu, Sheridan Holroyd, Kelsey Breslin, Teresa Ward, Wei Shi, Mary L Bath, Siddhartha Deb, Stephen B Fox, Gordon K Smyth, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2011  |  Molecular and Cellular Biology

Endoscopic management of post-cholecystectomy biliary fistula.

Michael W Hii, David E Gyorki, Kentaro Sakata, Richard J Cade, Simon W Banting

Journal article  |  2011  |  HPB

OBJECTIVE: Bile duct injury is an uncommon but potentially serious complication in cholecystectomy. A recognized treatment for min..

Management of synchronous tumours of the oesophagus and pancreatic head: a novel approach.

DE Gyorki, NE Clarke, MW Hii, SW Banting, RJ Cade

Journal article  |  2011  |  The Annals of The Royal College of Surgeons of England

Synchronous tumours of the oesophagus and pancreatic head are very rare. This report describes a unique case of an adenocarcinoma ..

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

Elgene Lim, Francois Vaillant, Di Wu, Natasha C Forrest, Bhupinder Pal, Adam H Hart, Marie-Liesse Asselin-Labat, David E Gyorki, Teresa Ward, Audrey Partanen, Frank Feleppa, Lily I Huschtscha, Heather J Thorne, Stephen B Fox, Max Yan, Juliet D French, Melissa A Brown, Gordon K Smyth, Jane E Visvader, Geoffrey J Lindeman

Journal article  |  2009  |  Nature Medicine

Resident macrophages influence stem cell activity in the mammary gland

David E Gyorki, Marie-Liesse Asselin-Labat, Nico van Rooijen, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2009  |  Breast Cancer Research