Paul Donnelly

Examination of N,N-dimethylbenzylamine as a substrate for ruthenium-catalysed C-H (thio)amidation: A mass spectrometry and DFT directed study

Weam AO Altalhi, Alasdair I McKay, Benjamin Spyrou, Allan J Canty, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2021  |  JOURNAL OF ORGANOMETALLIC CHEMISTRY

Key steps in the potential application of N,N-dimethylbenzylamine, a widely used substrate in organometallic chemistry, in rutheni..

Collagen-Targeted Peptides for Molecular Imaging of Diffuse Cardiac Fibrosis.

Martin Ezeani, Asif Noor, Karen Alt, Sean Lal, Paul S Donnelly, Christoph E Hagemeyer, Be'eri Niego

Journal article  |  2021  |  J Am Heart Assoc

Background Cardiac fibrosis is the excessive deposition of extracellular matrix in the heart, triggered by a cardiac insult, aging..

Oxorhenium(V) and Oxotechnetium(V) Complexes of N3S Tetradentate Ligands with a Styrylpyridyl Functional Group: Toward Imaging Agents to Assist in the Diagnosis of Alzheimer's Disease.

Benjamin Spyrou, Ingebjørg N Hungnes, Filipa Mota, Jayanta Bordoloi, Philip J Blower, Jonathan M White, Michelle T Ma, Paul S Donnelly

Journal article  |  2021  |  Inorg Chem

Alzheimer's disease (AD) is associated with the presence of amyloid plaques in the brain mainly comprised of aggregated forms of a..

Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB (R) Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models (Jul, 10.1007/s11307-021-01620-1, 2021)

Vasilios Liapis, William Tieu, Nicole L Wittwer, Tessa Gargett, Andreas Evdokiou, Prab Takhar, Stacey E Rudd, Paul S Donnelly, Michael P Brown, Alexander H Staudacher

Journal article  |  2021  |  MOLECULAR IMAGING AND BIOLOGY

This article was updated to amend the Acknowledgments.

Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB (R) Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models

Vasilios Liapis, William Tieu, Nicole L Wittwer, Tessa Gargett, Andreas Evdokiou, Prab Takhar, Stacey E Rudd, Paul S Donnelly, Michael P Brown, Alexander H Staudacher

Journal article  |  2021  |  MOLECULAR IMAGING AND BIOLOGY

PURPOSE: Early detection of tumor treatment responses represents an unmet clinical need with no approved noninvasive methods. DAB4..

Imaging Somatostatin Positive Tumors with Tyr(3)-Octreotate/Octreotide Conjugated to Desferrioxamine B Squaramide Radiolabeled with either Zirconium-89 or Gallium-68

Asif Noor, Jessica K Van Zuylekom, Stacey E Rudd, Peter D Roselt, Mohammad B Haskali, Eddie Yan, Michael Wheatcroft, Rodney J Hicks, Carleen Cullinane, Paul S Donnelly

Journal article  |  2021  |  BIOCONJUGATE CHEMISTRY

Radiolabeled derivatives of Tyr3-octreotide and Tyr3-octreotate, synthetic analogues of the peptide hormone somatostatin, can be u..

Therapeutic Efficacy of a Bivalent Inhibitor of Prostate-Specific Membrane Antigen Labeled with( 67)Cu

Lachlan E McInnes, Carleen Cullinane, Peter D Roselt, Susan Jackson, Benjamin J Blyth, Ellen M van Dam, Nicholas A Zia, Matthew J Harris, Rodney J Hicks, Paul S Donnelly

Journal article  |  2021  |  JOURNAL OF NUCLEAR MEDICINE

Radionuclide therapy targeting prostate-specific membrane antigen (PSMA) is promising for prostate cancer. We previously reported ..

Enzyme mediated incorporation of zirconium-89 or copper-64 into a fragment antibody for same day imaging of epidermal growth factor receptor

Stacey E Rudd, Jessica K Van Zuylekom, Anna Raicevic, Lesley A Pearce, Carleen Cullinane, Charlotte C Williams, Timothy E Adams, Rodney J Hicks, Paul S Donnelly

Journal article  |  2021  |  CHEMICAL SCIENCE

Identification of tumors which over-express Epidermal Growth Factor Receptor (EGFR) is important in selecting patients for anti-EG..

A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls

James H McMahon, Jennifer M Zerbato, Jillian SY Lau, Jaclyn L Lange, Michael Roche, Carolin Tumpach, Ashanti Dantanarayana, Ajantha Rhodes, Judy Chang, Thomas A Rasmussen, Charlene A Mackenzie, Karen Alt, Michelle Hagenauer, Janine Roney, Jessica O'Bryan, Alexandra Carey, Richard McIntyre, Paul Beech, Graeme J O'Keefe, Christian W Wichmann, et al.

Journal article  |  2021  |  EBIOMEDICINE

BACKGROUND: A research priority in finding a cure for HIV is to establish methods to accurately locate and quantify where and how ..

Metallic radionuclides for diagnostic imaging and cancer radiotherapy: The development of theragnostic matched pairs and targeted alpha therapy

KA Morgan, PS Donnelly

Journal article  |  2021  |  Advances in inorganic chemistry

This account highlights the development of theragnostic pairs of radionuclides for imaging and therapy. The current use of diagnos..