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Prof

Paul Donnelly

Professor In Chemistry
Chemistry
radiopharmaceuticals
coordination chemistry
transition metal chemistry
bioinorganic chemistry
macrocycles
inorganic synthesis
science & technology
physical sciences
chemistry
Paul Donnelly's Profile Picture
Prof

Paul Donnelly

 
Division
Science
 
Primary Interest
Inorganic Chemistry and Metals in Medicine
Paul Donnelly's Profile Picture
Prof

Paul Donnelly

 

Projects

Displaying the 66 most recent projects by Paul Donnelly.

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Diagnostic Imaging And Therapy Of Cancers With Copper Radiopharmaceuticals

2020 - 2023
Active
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Imcrc Project Agreement - Centralised Manufacture Of Molecularly-Targeted Radiation Drug Products For Treatment Of Cancer

2020 - 2022
Active
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Discovering New Chemistry And Potential Applications Of Metal Tetrapyrroles

2020 - 2022
Active
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New Theranostic Agents Based On Copper-64 And Copper-67.

2019 - 2020
Active
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Collaboration Agreement (Academic) - Novel Peptide-Based Imaging Probes For Brain Cancer Targets And Biologic Pathways

2019 - 2023
Active
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ARC Training Centre For The Chemical Industries (UOM Contribution)

The ARC Training Centre for the Chemical Industries will foster a world-class environment of transformative innovative research in Australia..

2018 - 2023
Active
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ARC Training Centre For The Chemical Industries (Arc-Qiao Child)

The ARC Training Centre for the Chemical Industries will foster a world-class environment of transformative innovative research in Australia..

2018 - 2023
Active
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Metal-Promoted Bond Functionalisation: New Routes To Amides And Thioamides

This project aims to discover new metal-promoted methods to synthesise amides and thioamides, important structural motifs in chemistry and b..

2018 - 2021
Active
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Cryogenic Quantum Microscope Facility (ARC Cash)

This project aims to establish a cryogenic, quantum microscope facility in Australia. Quantum sensing is a new field that harnesses the prop..

2018 - 2018
Completed
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Cryogenic Quantum Microscope Facility (NON-ARC Cash)

This project aims to establish a cryogenic, quantum microscope facility in Australia. Quantum sensing is a new field that harnesses the prop..

2018 - 2018
Completed
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A Therapeutic Copper Compound To Treat Progressive Multiple Sclerosis

2018 - 2020
Active
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Alpha Particle Therapy Of Solid Tumours (Non Lead)

Alpha-particles linked to recombinant antibodies targeting tumour cells have potential to effectively treat tumours while minimising normal ..

2018 - 2020
Active
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Zirconium-89 Radiolabeled Antibody For Pre-Clinical Inflammation Imaging

2017 - 2018
Completed
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Zirconium-89 Based Immunodiagnostics

2017 - 2019
Completed
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Lead Optimisation Studies Lex29446

2017 - 2017
Completed
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Targeting A Deregulated Copper-Iron Axis To Treat Sporadic Mnd: A Combination Treatment Strategy

2017 - 2020
Completed
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Building An Immunocompetent Alzheimer'S Disease Brain-On-A-Chip

New human cell culture models of Alzheimer's disease are urgently needed to help translate drugs into successful patient outcomes. In this p..

2017 - 2019
Completed
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Preparative High Performance Liquid Chromatography System

2016 - 2017
Completed
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Collaborative Research Agreement Between Olivia Newton-John Cancer Research Institute (Onjcri) And Uom (Donnelly)

2016 - 2019
Completed
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Gallium, Copper And Metal Fluoride Complexes Designed For Brain Imaging

This project aims to develop fundamental synthetic coordination chemistry directed toward the development of new agents for imaging brain pe..

2016 - 2019
Completed
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Gallium, Copper And Metal Fluoride Complexes Designed For Brain Imaging

This project aims to develop fundamental synthetic coordination chemistry directed toward the development of new agents for imaging brain pe..

2016 - 2019
Completed
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Technetium And Copper Complexes For Diagnostic Imaging Of Neurodegeneration

This project aims to develop new synthetic coordination chemistry for making metal complexes to assist in the diagnosis of neurodegeneration..

2016 - 2019
Completed
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Molecular Imaging Of Cancers With Copper And Zirconium Radiopharmaceuticals

This research aims to develop new imaging agents to assist in the diagnosis of breast cancer. This research will advance knowledge in the ar..

2016 - 2019
Completed
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Molecular Imaging Of Cancers With Copper And Zirconium Radiopharmaceuticals

This research aims to develop new imaging agents to assist in the diagnosis of breast cancer. This research will advance knowledge in the ar..

2016 - 2019
Completed
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Supply Of Services Agreement Between Clarity Pharmaceuticals And The University Of Melbourne

2015 - 2022
Active
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Technetium And Copper Complexes For Diagnostic Imaging Of Neurodegeneration

2015 - 2015
Completed
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Supply Of Services Agreement

2014 - 2015
Completed
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Site-Specific Conjugation Of Zirconium And Copper Complexes To Antibodies For Application In Diagnostic Imaging And Therapy

This project will focus on fundamental chemistry that underpins innovations in the synthesis of metal-based imaging and therapeutic agents. ..

2014 - 2017
Completed
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Harnessing The Consequences Of Impaired Mitochondrial Energy Metabolism To Treat The Symptoms Of Age-Related Neuronal Decline

Cognitive function and locomotor ability decline due to advanced age and disorders such as motor neuron disease, Alzheimer’s and Parkinson’s..

2014 - 2016
Completed
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Harnessing The Consequences Of Impaired Mitochondrial Energy Metabolism To Treat The Symptoms Of Age-Related Neuronal Decline

Cognitive function and locomotor ability decline due to advanced age and disorders such as motor neuron disease, Alzheimer’s and Parkinson’s..

2014 - 2016
Completed
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Site-Specific Conjugation Of Zirconium And Copper Complexes To Antibodies For Application In Diagnostic Imaging And Therapy

This project will focus on fundamental chemistry that underpins innovations in the synthesis of metal-based imaging and therapeutic agents. ..

2014 - 2017
Completed
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Harnessing The Consequences Of Impaired Mitochondrial Energy Metabolism To Treat The Symptoms Of Age-Related Neuronal Decline

Cognitive function and locomotor ability decline due to advanced age and disorders such as motor neuron disease, Alzheimer’s and Parkinson’s..

2014 - 2016
Completed
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Research Synthesis And Development Of Metal Based Complexes For The Treatment Of Neurodegenerative Diseases

2013 - 2014
Completed
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Copper And Gallium Radiopharmaceuticals For The Diagnosis And Therapy Of Cancer

The goal of this project is to develop the chemistry required to prepare molecular imaging and therapeutic agents for the diagnosis and trea..

2012 - 2015
Completed
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Copper And Gallium Radiopharmaceuticals For The Diagnosis And Therapy Of Cancer

The goal of this project is to develop the chemistry required to prepare molecular imaging and therapeutic agents for the diagnosis and trea..

2012 - 2015
Completed
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Research Synthesis And Development Of Metal Based Complexes For The Treatment Of Neurodegenerative Diseases

2012 - 2013
Completed
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Redox Sulfur Chemistry In Copper Nutrition

Problems with metabolism of the nutrient metal copper are associated with many diseases including tuberculosis, heart disease and Alzheimer'..

2012 - 2015
Completed
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Copper Complexes For The Diagnostic Imaging Of Alzheimer'S Disease

This research will develop new chemistry to produce new imaging agents for earlier and more accurate diagnosis of Alzheimer's disease.

2012 - 2015
Completed
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Novel Targeted Pet Nanoparticles For Diagnosis Of Thrombosis, Inflammation And Prevention Of Myocardial Infection.

The aim of this project is to develop novel targeted positron emission tomography imaging agents that seek out specific markers for various ..

2012 - 2014
Completed
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Novel Therapies For Neurodegenerative Diseases

Exitotoxicity has been implicated in many neurological disorders incluing Alzheimer's and Huntington's disesaes. This toxicity can be inhibi..

2012 - 2014
Completed
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Contract Research In To The Synthesis Of New Radiopharmaceuticals

2011 - 2011
Completed
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Targeting Tdp-43 To Treat Neurodegenerative Diseases

2011 - 2011
Completed
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Targetting Calcineurin To Treat Alzheimer'S Disease

2011 - 2011
Completed
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Testing A New Treatment For Motor Neuron Disease

ALS is a form of motor neuron disease that quickly renders people paralysed by killing off the nerves needed for muscle control. It affects ..

2011 - 2013
Completed
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Testing A New Treatment For Motor Neuron Disease

ALS is a form of motor neuron disease that quickly renders people paralysed by killing off the nerves needed for muscle control. It affects ..

2011 - 2013
Completed
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Targetting Calcineurin With A Metal-Ligand Complex To Treat Alzheimer'S Disease

2011 - 2011
Completed
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Targeting Tdp-43 To Treat Neurodegenerative Diseases

2011 - 2011
Completed
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Targetting Calcineurin With A Metal-Ligand Complex To Treat Alzheimer'S Disease

2011 - 2011
Completed
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Small Molecule X-Ray Molecular Structure Elucidation Facility

X-ray diffraction plays a key role in identification and molecular characterisation. X-ray techniques are the single most widely used analyt..

2010 - 2011
Completed
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Investigating The In Vivo Targets Affected By A Novel Therapeutic Agent For Motor Neurone Disease

2010 - 2010
Completed
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Investigating Cellular Hypoxia As A Causative Factor In Mnd And As A Potential Therapeutic Target

2010 - 2010
Completed
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Modulation Of Cell Signalling By Metal-Based Compounds As A Therapeutic Treament For Alzheimer'S Disease.

Alzheimer's disease (AD) is an enormous burden on the Australian health care system . We have begun to investigate therapeutic treatments ba..

2009 - 2012
Completed
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Enhanced Capacity In Ultra-Trace Level Detection And Speciation Of Compounds Of Environmental, Biological And Materials Science Interest

The proposed integrated facility will strongly support collaborative research in areas of high national priority. These are environmental su..

2009 - 2009
Completed
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Application Of Copper-64 In Studies Of The Role Of Copper In Alzheimer'S Disease

2009 - 2009
Completed
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Modulation Of Cell Signalling By Metal-Based Compounds As A Therapeutic Treament For Alzheimer'S Disease.

Alzheimer's disease (AD) is an enormous burden on the Australian health care system . We have begun to investigate therapeutic treatments ba..

2009 - 2012
Completed
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Molecular Probes For Bio-Metals

The nutrient trace metals are essential to life. Problems with the metabolism of iron, copper and zinc are associated with neuro-degenerativ..

2008 - 2012
Completed
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The Use Of Cu-Atsm Treatment To Identify Cellular Mechanisms Of Motor Neuron Degeneration In Amyotrophic Lateral Sclerosis.

2008 - 2008
Completed
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Investigating Protein/Protein Interactions

To establish and maintain a prominent position in scientific research, Australian scientists must have access to state of the art technology..

2008 - 2009
Completed
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New Copper And Rhenium Radiopharmaceuticals

The aims of this project are to provide new metal-based radiopharmaceuticals for the treatment of cancer, and the imaging of cancer and othe..

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The Synthesis Of New Copper And Rhenium Chelators For Application In Medicine, Industry And Environment

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Application Of Copper-64 To Studies On Alzheimer'S Disease And Characterisation Of Novel Genes And Proteins Involved In Copper Homeostasis

Completed
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Copper Radiopharmaceuticals For Molecular Imaging Of Alzheimer'S Disease

The expected outcome of this research is to develop molecular agents to allow non-invasive diagnostic imaging of senile plaques associated w..

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X-Ray Molecular Structure Elucidation Facility (Msef)

X-ray diffraction plays a key role in identification and molecular characterization. X-ray techniques are the single most widely used analyt..

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Molecular Imaging Of Alzheimer'S Disease

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A National Biomedical Electron Paramagnetic Resonance And Molecular Imaging Centre

Multifrequency continuous wave and pulsed electron paramagnetic resonance spectroscopy and molecular imaging instrumentation will provide fo..

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Enhanced Capacity In Ultra-Trace Level Detection And Speciation Of Compounds Of Environmental, Biological And Materials Science Interest

The proposed integrated facility will strongly support collaborative research in areas of high national priority. These are environmental su..

66

Projects

Project Types

48

Research Grant

13

Research Contracts

5

Internal Research Grant

Scholarly Works

Displaying the 179 most recent scholarly works by Paul Donnelly.

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Preclinical Evaluation of a High-Affinity Sarcophagine-Containing PSMA Ligand for 64Cu/67Cu-Based Theranostics in Prostate Cancer.

James M Kelly, Shashikanth Ponnala, Alejandro Amor-Coarasa, Nicholas A Zia, Anastasia Nikolopoulou, Clarence Williams, David J Schlyer, Stephen G DiMagno, Paul S Donnelly, John W Babich

Journal article  |  2020  |  Molecular Pharmaceutics

The application of small molecules targeting prostate-specific membrane antigen (PSMA) has emerged as a highly promising clinical ..

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Charge neutral rhenium tricarbonyl complexes of tridentate N-heterocyclic carbene ligands that bind to amyloid plaques of Alzheimer's disease

Nuchareenat Wiratpruk, Asif Noor, Catriona A McLean, Paul S Donnelly, Peter J Barnard

Journal article  |  2020  |  Dalton Transactions

Two tridentate ligand systems bearing N-heterocyclic carbene (NHC), amine and carboxylate donor groups coupled to benzothiazole- o..

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Identification of the Side Products That Diminish the Yields of the Monoamidated Product in Metal-Catalyzed C-H Amidation of 2-Phenylpyridine with Arylisocyanates

Alasdair I McKay, Weam AO Altalhi, Lachlan E McInnes, Milena L Czyz, Allan J Canty, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2020  |  The Journal of Organic Chemistry

The Ru(II)-catalyzed amidation of 2-arylpyridines with aryl isocyanates via C-H bond activation is less efficient than described p..

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Palladium-Mediated CO2 Extrusion Followed by Insertion of Isocyanates for the Synthesis of Benzamides: Translating Fundamental Mechanistic Studies To Develop a Catalytic Protocol

Yang Yang, Allan J Canty, Alasdair McKay, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2020  |  Organometallics

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Cu-II(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease

Adam Southon, Kathryn Szostak, Karla M Acevedo, Krista A Dent, Irene Volitakis, Abdel A Belaidi, Kevin J Barnham, Peter J Crouch, Scott Ayton, Paul S Donnelly, Ashley Bush

Journal article  |  2020  |  British Journal of Pharmacology

BACKGROUND AND PURPOSE: Diacetyl-bis(4-methyl-3-thiosemicarbazonato)copperII (CuII (atsm)) ameliorates neurodegeneration and delay..

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A conceptual framework for the development of iridium(iii) complex-based electrogenerated chemiluminescence labels

Lifen Chen, David J Hayne, Egan H Doeven, Johnny Agugiaro, David JD Wilson, Luke C Henderson, Timothy U Connell, Yi Heng Nai, Richard Alexander, Serena Carrara, Conor F Hogan, Paul S Donnelly, Paul S Francis

Journal article  |  2019  |  Chemical Science

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A Sarcophagine Containing PSMA Ligand for Targeting Prostate Cancer with Cu-64/67

JM Kelly, S Ponnala, A Nikolopoulou, N Zia, C Williams, PS Donnelly, JW Babich

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

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Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium

Hannah A Pearce, Hongwei Qian, Timothy U Connell, Dexing Huang, Claudia Gottstein, Paul S Donnelly, Karlheinz Peter, Paul Gregorevic, Christoph E Hagemeyer

Journal article  |  2019  |  Molecular Therapy - Methods & Clinical Development

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A Bivalent Inhibitor of Prostate Specific Membrane Antigen Radiolabeled with Copper-64 with High Tumor Uptake and Retention

Nicholas A Zia, Carleen Cullinane, Jessica K Van Zuylekom, Kelly Waldeck, Lachlan E McInnes, Gojko Buncic, Mohammad B Haskali, Peter D Roselt, Rodney J Hicks, Paul S Donnelly

Journal article  |  2019  |  Angewandte Chemie International Edition

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An effective cis-beta-octahedral Mn(iii) SALPN catalyst for the Mukaiyama-Isayama hydration of alpha,beta-unsaturated esters

Paul S Donnelly, Andrea J North, Natalia Caren Radjah, Michael Ricca, Angus Robertson, Jonathan M White, Mark A Rizzacasa

Journal article  |  2019  |  Chemical Communications

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Cu-64-SARTATE PET Imaging of Patients with Neuroendocrine Tumors Demonstrates High Tumor Uptake and Retention, Potentially Allowing Prospective Dosimetry for Peptide Receptor Radionuclide Therapy

Rodney J Hicks, Price Jackson, Grace Kong, Robert E Ware, Michael S Hofman, David A Pattison, Timothy A Akhurst, Elizabeth Drummond, Peter Roselt, Jason Callahan, Roger Price, Charmaine M Jeffery, Emily Hong, Wayne Noonan, Alan Herschtal, Lauren J Hicks, Amos Hedt, Matthew Harris, Brett M Paterson, Paul S Donnelly

Journal article  |  2019  |  Journal of Nuclear Medicine

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Development of a new bifunctional PSMA ligand as a theranostic for prostate cancer

Nicholas Zia, Carleen Cullinane, Jessica Van Zuylekom, Mohammad Haskali, Peter Roselt, Ellen van Dam, Matthew Harris, Rodney Hicks, Paul Donnelly

Conference Proceedings  |  2019  |  JOURNAL OF NUCLEAR MEDICINE

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Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies

Jiwei Cui, Yi Ju, Zachary H Houston, Joshua J Class, Nicholas L Fletcher, Sheilajen Alcantara, Qiong Dai, Christopher B Howard, Stephen M Mahler, Adam K Wheatley, Robert De Rose, Paul T Brannon, Brett M Paterson, Paul S Donnelly, Kristoferj Thurecht, Frank Caruso, Stephen J Kent

Journal article  |  2019  |  Advanced Healthcare Materials

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Modification of Biodistribution and Brain Uptake of Copper Bis(thiosemicarbazonato) Complexes by the Incorporation of Amine and Polyamine Functional Groups

Brett M Paterson, Carleen Cullinane, Peter J Crouch, Anthony R White, Kevin J Barnham, Peter D Roselt, Wayne Noonan, David Binns, Rodney J Hicks, Paul S Donnelly

Journal article  |  2019  |  Inorganic Chemistry

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Potential Diagnostic Imaging of Alzheimer's Disease with Copper-64 Complexes That Bind to Amyloid-beta Plaques

Lachlan E McInnes, Asif Noor, Kai Kysenius, Carleen Cullinane, Peter Roselt, Catriona A McLean, Francis CK Chiu, Andrew K Powell, Peter J Crouch, Jonathan M White, Paul S Donnelly

Journal article  |  2019  |  Inorganic Chemistry

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Desulfination versus decarboxylation as a means of generating three-and five-coordinate organopalladium complexes [(phen)(n)Pd(C6H5)]( ) (n=1 and 2) to study their fundamental bimolecular reactivity

Zilin Wang, Yang Yang, Paul S Donnelly, Allan J Canty, Richard AJ O'Hair

Journal article  |  2019  |  Journal of Organometallic Chemistry

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Synthesis of Amidines by Palladium-Mediated CO2 Extrusion Followed by Insertion of Carbodiimides: Translating Mechanistic Studies to Develop a One-Pot Method

Yang Yang, Asif Noor, Allan J Canty, Alireza Ariafard, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2019  |  Organometallics

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A Copper Complex of a Thiosemicarbazone-Pyridylhydrazone Ligand Containing a Vinylpyridine Functional Group as a Potential Imaging Agent for Amyloid-beta Plaques

Lachlan E McInnes, Asif Noor, Peter D Roselt, Catriona A McLean, Jonathan M White, Paul S Donnelly

Journal article  |  2019  |  Australian Journal of Chemistry

Complexes containing positron-emitting radionuclides of copper have the potential to be of use for diagnostic imaging with positro..

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Labelling proteins and peptides with phosphorescent d(6) transition metal complexes

Timothy U Connell, Paul S Donnelly

Journal article  |  2018  |  Coordination Chemistry Reviews

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Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies

Simon McKenzie-Nickson, Jacky Chan, Keyla Perez, Lin W Hung, Lesley Cheng, Amelia Sedjahtera, Lydia Gunawan, Paul A Adlard, David J Hayne, Lachlan E McInnes, Paul S Donnelly, David Finkelstein, Andrew F Hill, Kevin J Barnham

Journal article  |  2018  |  ACS Chemical Neuroscience

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The social defeat/overcrowding murine psychosocial stress model results in a pharmacologically reversible body weight gain but not depression - related behaviours

Ryan J Keenan, Jacky Chan, Paul S Donnelly, Kevin J Barnham, Laura H Jacobson

Journal article  |  2018  |  Neurobiology of Stress

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Rhenium and technetium complexes of thioamide derivatives of pyridylhydrazine that bind to amyloid-beta plaques

Scott P Fletcher, Asif Noor, James L Hickey, Catriona A McLean, Jonathan M White, Paul S Donnelly

Journal article  |  2018  |  JBIC Journal of Biological Inorganic Chemistry

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Cu-II(atsm) Attenuates Neuroinflammation

Xin Yi Choo, Jeffrey R Liddell, Mikko T Huuskonen, Alexandra Grubman, Diane Moujalled, Jessica Roberts, Kai Kysenius, Lauren Patten, Hazel Quek, Lotta E Oikari, Clare Duncan, Simon A James, Lachlan E McInnes, David J Hayne, Paul S Donnelly, Eveliina Pollari, Suvi Vahatalo, Katarina Lejavova, Mikko Kettunen, Tarja Malm, et al.

Journal article  |  2018  |  Frontiers in Neuroscience

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Mixed annihilation electrogenerated chemiluminescence of iridium(iii) complexes

Lachlan C Soulsby, David J Hayne, Egan H Doeven, David JD Wilson, Johnny Agugiaro, Timothy U Connell, Lifen Chen, Conor F Hogan, Emily Kerr, Jacqui L Adcock, Paul S Donnelly, Jonathan M White, Paul S Francis

Journal article  |  2018  |  Physical Chemistry Chemical Physics

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Comparing the therapeutic efficacy of Cu-67-SARTATE and (17)7Lu-DOTA-octreotate in a neuroendocrine tumor model

Carleen Cullinane, Charmaine Jeffery, Rachael Walker, Peter Roselt, David Binns, Ellen van Dam, Matthew Harris, Paul Donnelly, Rodney Hicks

Conference Proceedings  |  2018  |  JOURNAL OF NUCLEAR MEDICINE

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Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P-Glycoprotein Mediated Efflux

Karla M Acevedo, David J Hayne, Lachlan E McInnes, Asif Noor, Clare Duncan, Diane Moujalled, Irene Volitakis, Angela Rigopoulos, Kevin J Barnham, Victor L Villemagne, Anthony R White, Paul S Donnelly

Journal article  |  2018  |  Journal of Medicinal Chemistry

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Copper, gallium and zirconium positron emission tomography imaging agents: The importance of metal ion speciation

Lachlan E McInnes, Stacey E Rudd, Paul S Donnelly

Journal article  |  2017  |  Coordination Chemistry Reviews

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Electron paramagnetic resonance microscopy using spins in diamond under ambient conditions

David A Simpson, Robert G Ryan, Liam T Hall, Evgeniy Panchenko, Simon C Drew, Steven Petrou, Paul S Donnelly, Paul Mulvaney, Lloyd CL Hollenberg

Journal article  |  2017  |  Nature Communications

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Rhenium and Technetium-oxo Complexes with Thioamide Derivatives of Pyridylhydrazine Bifunctional Chelators Conjugated to the Tumour Targeting Peptides Octreotate and Cyclic-RGDfK

Andrea J North, John A Karas, Michelle T Ma, Philip J Blower, Uwe Ackermann, Jonathan M White, Paul S Donnelly

Journal article  |  2017  |  Inorganic Chemistry

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Frontispiz: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Brett M Paterson, Keith F White, Jonathan M White, Brendan F Abrahams, Paul S Donnelly

Journal article  |  2017  |  Angewandte Chemie

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Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Brett M Paterson, Keith F White, Jonathan M White, Brendan F Abrahams, Paul S Donnelly

Journal article  |  2017  |  Angewandte Chemie

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Frontispiece: Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Brett M Paterson, Keith F White, Jonathan M White, Brendan F Abrahams, Paul S Donnelly

Journal article  |  2017  |  Angewandte Chemie International Edition

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Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes

Brett M Paterson, Keith F White, Jonathan M White, Brendan F Abrahams, Paul S Donnelly

Journal article  |  2017  |  Angewandte Chemie International Edition

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The efficient synthesis and purification of amyloid-beta(1-42) using an oligoethylene glycol-containing photocleavable lysine tag

John A Karas, Asif Noor, Christine Schieber, Timothy U Connell, Frances Separovic, Paul S Donnelly

Journal article  |  2017  |  Chemical Communications

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Tunable Porous Coordination Polymers for the Capture, Recovery and Storage of Inhalation Anesthetics

Brendan F Abrahams, A David Dharma, Paul S Donnelly, Timothy A Hudson, Cameron J Kepert, Richard Robson, Peter D Southon, Keith F White

Journal article  |  2017  |  Chemistry - A European Journal

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Gas-Phase Structural and Optical Properties of Homo- and Heterobimetallic Rhombic Dodecahedral Nanoclusters [Ag14-nCun(C CtBu)(12)X]( ) (X = CI and Br): Ion Mobility, VUV and UV Spectroscopy, and DFT Calculations

Steven Daly, Chang Min Choi, Athanasios Zavras, Marjan Krstic, Fabien Chirot, Timothy U Connell, Spencer J Williams, Paul S Donnelly, Rodolphe Antoine, Alexandre Giuliani, Vlasta Bonaseic-Koutecky, Philippe Dugourd, Richard AJ O'Hair

Journal article  |  2017  |  The Journal of Physical Chemistry C

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A one-pot route to thioamides discovered by gas-phase studies: palladium-mediated CO2 extrusion followed by insertion of isothiocyanates

Asif Noor, Jiawei Li, George N Khairallah, Zhen Li, Hossein Ghari, Allan J Canty, Alireza Ariafard, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2017  |  Chemical Communications

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The Copper bis(thiosemicarbazone) Complex Cu-II(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu

Mikko T Huuskonen, Qing-zhang Tuo, Sanna Loppi, Hiramani Dhungana, Paula Korhonen, Lachlan E McInnes, Paul S Donnelly, Alexandra Grubman, Sara Wojciechowski, Katarina Lejavova, Yuriy Pomeshchik, Laura Periviita, Lotta Kosonen, Martina Giordano, Frederick R Walker, Rong Liu, Ashley I Bush, Jari Koistinaho, Tarja Malm, Anthony R White, et al.

Journal article  |  2017  |  Neurotherapeutics

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Rhenium(I) complexes of N-heterocyclic carbene ligands that bind to amyloid plaques of Alzheimer's disease

Chung Ying Chan, Asif Noor, Catriona A McLean, Paul S Donnelly, Peter J Barnard

Journal article  |  2017  |  Chemical Communications

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Cu-II(atsm) improves the neurological phenotype and survival of SOD1(G93A) mice and selectively increases enzymatically active SOD1 in the spinal cord

James B Hilton, Stephen W Mercer, Nastasia KH Lim, Noel G Faux, Gojko Buncic, Joseph S Beckman, Blaine R Roberts, Paul S Donnelly, Anthony R White, Peter J Crouch

Journal article  |  2017  |  Scientific Reports

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Targeting Activated Platelets: A Unique and Potentially Universal Approach for Cancer Imaging

May Lin Yap, James D McFadyen, Xiaowei Wang, Nicholas A Zia, Jan David Hohmann, Melanie Ziegler, Yu Yao, Alan Pham, Matthew Harris, Paul S Donnelly, P Mark Hogarth, Geoffrey A Pietersz, Bock Lim, Karlheinz Peter

Journal article  |  2017  |  Theranostics

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Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets

Melanie Ziegler, Karen Alt, Brett M Paterson, Peter Kanellakis, Alex Bobik, Paul S Donnelly, Christoph E Hagemeyer, Karlheinz Peter

Journal article  |  2016  |  Scientific Reports

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Synthesis, Structural Characterization, and Gas-Phase Unimolecular Reactivity of Bis(diphenylphosphino)amino Copper Hydride Nanoclusters [Cu-3(X)(mu(3)-H)((PPh2)(2)NH)(3)](BF4), Where X = mu(2)-Cl and mu(3)-BH4

Jiaye Li, Jonathan M White, Roger J Mulder, Gavin E Reid, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2016  |  Inorganic Chemistry

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A gallium(III) Schiff base-curcumin complex that binds to amyloid-beta plaques

Jaclyn L Lange, David J Hayne, Peter Roselt, Catriona A McLean, Jonathan M White, Paul S Donnelly

Journal article  |  2016  |  Journal of Inorganic Biochemistry

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Synthesis of Oxorhenium(V) and Oxotechnetium(V) Complexes That Bind to Amyloid-beta Plaques

David J Hayne, Jonathan M White, Catriona A McLean, Victor L Villemagne, Kevin J Barnham, Paul S Donnelly

Journal article  |  2016  |  Inorganic Chemistry

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Synthesis of Homochiral Co-III- and Mn-IV-[2.2]Paracyclophane Schiff Base Complexes with Predetermined Chirality at the Metal Centre

Darran Loits, Stefan Braese, Andrea J North, Jonathan M White, Paul S Donnelly, Mark A Rizzacasa

Journal article  |  2016  |  European Journal of Inorganic Chemistry

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Luminescent Iridium(111) Cyclometalated Complexes with 1,2,3-Triazole "Click" Ligands

Timothy U Connell, Jonathan M White, Trevor A Smith, Paul S Donnelly

Journal article  |  2016  |  Inorganic Chemistry

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Macrocyclic Bifunctional Chelators and Conjugation Strategies for Copper-64 Radiopharmaceuticals

Brett M Paterson, Paul S Donnelly

Journal article  |  2016  |  ADVANCES IN INORGANIC CHEMISTRY, VOL 68: INSIGHTS FROM IMAGING IN BIOINORGANIC CHEMISTRY

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Macrocyclic Bifunctional Chelators and Conjugation Strategies for Copper-64 Radiopharmaceuticals

P DONNELLY, B paterson

Book Chapter  |  2016

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Analytically useful blue chemiluminescence from a water-soluble iridium(III) complex containing a tetraethylene glycol functionalised triazolylpyridine ligand

Zoe M Smith, Emily Kerr, Egan H Doeven, Timothy U Connell, Neil W Barnett, Paul S Donnelly, Stephen J Haswell, Paul S Francis

Journal article  |  2016  |  The Analyst

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New perspectives on the annihilation electrogenerated chemiluminescence of mixed metal complexes in solution

Emily Kerr, Egan H Doeven, Gregory J Barbante, Conor F Hogan, David J Hayne, Paul S Donnelly, Paul S Francis

Journal article  |  2016  |  Chemical Science

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A desferrioxamine B squaramide ester for the incorporation of zirconium-89 into antibodies (vol 52, 11889, 2016)

Stacey E Rudd, Peter Roselt, Carleen Cullinane, Rodney J Hicks, Paul S Donnelly

Journal article  |  2016  |  Chemical Communications

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A desferrioxamine B squaramide ester for the incorporation of zirconium-89 into antibodies

Stacey E Rudd, Peter Roselt, Carleen Cullinane, Rodney J Hicks, Paul S Donnelly

Journal article  |  2016  |  Chemical Communications

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In Vitro and In Vivo Evaluation of Zr-89-DS-8273a as a Theranostic for Anti-Death Receptor 5 Therapy

Ingrid JG Burvenich, Fook-Thean Lee, Nancy Guo, Hui K Gan, Angela Rigopoulos, Adam C Parslow, Graeme J O'Keefe, Sylvia J Gong, Henri Tochon-Danguy, Stacey E Rudd, Paul S Dormelly, Masakatsu Kotsuma, Toshiaki Ohtsuka, Giorgio Senaldi, Andrew M Scott

Journal article  |  2016  |  Theranostics

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Blue Electrogenerated Chemiluminescence from Water-Soluble Iridium Complexes Containing Sulfonated Phenylpyridine or Tetraethylene Glycol Derivatized Triazolylpyridine Ligands

Emily Kerr, Egan H Doeven, Gregory J Barbante, Timothy U Connell, Paul S Donnelly, David JD Wilson, Trent D Ashton, Frederick M Pfeffer, Paul S Francis

Journal article  |  2015  |  Chemistry - A European Journal

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Intracellular Distribution of Fluorescent Copper and Zinc Bis(thiosemicarbazonato) Complexes Measured with Fluorescence Lifetime Spectroscopy

James L Hickey, Janine L James, Clare A Henderson, Katherine A Price, Alexandra I Mot, Gojko Buncic, Peter J Crouch, Jonathan M White, Anthony R White, Trevor A Smith, Paul S Donnelly

Journal article  |  2015  |  Inorganic Chemistry

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Toward Hypoxia-Selective Rhenium and Technetium Tricarbonyl Complexes

Andrea J North, David J Hayne, Christine Schieber, Katherine Price, Anthony R White, Peter J Crouch, Angela Rigopoulos, Graeme J O'Keefe, Henri Tochon-Danguy, Andrew M Scott, Jonathan M White, Uwe Ackermann, Paul S Donnelly

Journal article  |  2015  |  Inorganic Chemistry

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Copper(II)-Bis(Thiosemicarbazonato) Complexes as Antibacterial Agents: Insights into Their Mode of Action and Potential as Therapeutics

Karrera Y Djoko, Maira M Goytia, Paul S Donnelly, Mark A Schembri, William M Shafer, Alastair G McEwan

Journal article  |  2015  |  Antimicrobial Agents and Chemotherapy

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Protein Labelling with Versatile Phosphorescent Metal Complexes for Live Cell Luminescence Imaging

Timothy U Connell, Janine L James, Anthony R White, Paul S Donnelly

Journal article  |  2015  |  Chemistry – A European Journal

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Zn-II(atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism

Erin J McAllum, Blaine R Roberts, James L Hickey, Theresa N Dang, Alexandra Grubman, Paul S Donnelly, Jeffrey R Liddell, Anthony R White, Peter J Crouch

Journal article  |  2015  |  Neurobiology of Disease

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Mobile phone-based electrochemiluminescence sensing exploiting the 'USB On-The-Go' protocol

Egan H Doeven, Gregory J Barbante, Anthony J Harsant, Paul S Donnelly, Timothy U Connell, Conor F Hogan, Paul S Francis

Journal article  |  2015  |  Sensors and Actuators B: Chemical

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PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning

Timothy Johanssen, Nuttawat Suphantarida, Paul S Donnelly, Xiang M Liu, Steven Petrou, Andrew F Hill, Kevin J Barnham

Journal article  |  2015  |  Neurobiology of Disease

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Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer

Eleni Gourni, Luigi Del Pozzo, Emilie Kheirallah, Christiane Smerling, Beatrice Waser, Jean-Claude Reubi, Brett M Paterson, Paul S Donnelly, Philipp T Meyer, Helmut R Maecke

Journal article  |  2015  |  Molecular Pharmaceutics

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A Versatile Approach for the Site-Specific Modification of Recombinant Antibodies Using a Combination of Enzyme-Mediated Bioconjugation and Click Chemistry

Karen Alt, Brett M Paterson, Erik Westein, Stacey E Rudd, Stan S Poniger, Shweta Jagdale, Katie Ardipradja, Timothy U Connell, Guy Y Krippner, Ashish KN Nair, Xiaowei Wang, Henri J Tochon-Danguy, Paul S Donnelly, Karlheinz Peter, Christoph E Hagemeyer

Journal article  |  2015  |  Angewandte Chemie International Edition

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The Ionic Charge of Copper-64 Complexes Conjugated to an Engineered Antibody Affects Biodistribution

Jason LJ Dearing, Brett M Paterson, Vamsidhar Akurathi, Soledad Betanzos-Lara, S Ted Treves, Stephan D Voss, Jonathan M White, James S Huston, Suzanne V Smith, Paul S Donnelly, Alan B Packard

Journal article  |  2015  |  Bioconjugate Chemistry

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Engineering Poly(ethylene glycol) Particles for Improved Biodistribution

Jiwei Cui, Robert De Rose, Karen Alt, Sheilajen Alcantara, Brett M Paterson, Kang Liang, Ming Hu, Joseph J Richardson, Yan Yan, Charmaine M Jeffery, Roger I Price, Karlheinz Peter, Christoph E Hagemeyer, Paul S Donnelly, Stephen J Kent, Frank Caruso

Journal article  |  2015  |  ACS Nano

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Rhenium and technetium complexes that bind to amyloid-beta plaques

David J Hayne, Andrea J North, Michelle Fodero-Tavoletti, Jonathan M White, Lin W Hung, Angela Rigopoulos, Catriona A McLean, Paul A Adlard, Uwe Ackermann, Henri Tochon-Danguy, Victor L Villemagne, Kevin J Barnham, Paul S Donnelly

Journal article  |  2015  |  Dalton Transactions

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Annihilation electrogenerated chemiluminescence of mixed metal chelates in solution: modulating emission colour by manipulating the energetics

Emily Kerr, Egan H Doeven, Gregory J Barbante, Conor F Hogan, David J Bower, Paul S Donnelly, Timothy U Connell, Paul S Francis

Journal article  |  2015  |  Chemical Science

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Bifunctional Cu-64-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography

Brett M Paterson, Gojko Buncic, Lachlan E McInnes, Peter Roselt, Carleen Cullinane, David S Binns, Charmaine M Jeffery, Roger I Price, Rodney J Hicks, Paul S Donnelly

Journal article  |  2015  |  Dalton Transactions

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A set of robust fluorescent peptide probes for quantification of Cu(II) binding affinities in the micromolar to femtomolar range

Tessa R Young, Chathuri JK Wijekoon, Benjamin Spyrou, Paul S Donnelly, Anthony G Wedd, Zhiguang Xiao

Journal article  |  2015  |  Metallomics

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[Re(CO)(3)]( ) Complexes of exo-Functionalized Tridentate "Click" Macrocycles: Synthesis, Stability, Photophysical Properties, Bioconjugation, and Antibacterial Activity

Asif Noor, Gregory S Huff, Sreedhar V Kumar, James EM Lewis, Brett M Paterson, Christine Schieber, Paul S Donnelly, Heather JL Brooks, Keith C Gordon, Stephen C Moratti, James D Crowley

Journal article  |  2014  |  Organometallics

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Decarboxylative-Coupling of Allyl Acetate Catalyzed by Group 10 Organometallics, Uphen)M(CH3)]( )

Matthew Woolley, Alireza Ariafard, George N Khairalah, Kim Hong-Yin Kwan, Paul S Donnelly, Jonathan M White, Allan J Canty, Brian F Yates, Richard AJ O'Hair

Journal article  |  2014  |  The Journal of Organic Chemistry

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Direct versus Water-Mediated Protodecarboxylation of Acetic Acid Catalyzed by Group 10 Carboxylates, [(phen)M(O2CCH3)]( )

Matthew Woolley, George N Khairallah, Gabriel da Silva, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2014  |  Organometallics

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Single-Chain Antibody Conjugated to a Cage Amine Chelator and Labeled with Positron-Emitting Copper-64 for Diagnostic Imaging of Activated Platelets

Karen Alt, Brett M Paterson, Katie Ardipradja, Christine Schieber, Gojko Buncic, Bock Lim, Stan S Poniger, Bjoern Jakoby, Xiaowei Wang, Graeme J O'Keefe, Henri J Tochon-Dansuy, Andrew M Scott, Uwe Ackermann, Karlheinz Peter, Paul S Donnelly, Christoph E Hagemeyer

Journal article  |  2014  |  Molecular Pharmaceutics

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Synthesis, Structural Characterization, and Gas-Phase Unimolecular Reactivity of the Silver Hydride Nanocluster [Ag-3((PPh2)(2)CH2)(3)(mu(3)-H)](BF4)(2)

Athanasios Zavras, George N Khairallah, Timothy U Connell, Jonathan M White, Alison J Edwards, Roger J Mulder, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2014  |  Inorganic Chemistry

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Copper and Silver Complexes of Tris(triazole)amine and Tris(benzimidazole)amine Ligands: Evidence that Catalysis of an Azide-Alkyne Cycloaddition ("Click") Reaction by a Silver Tris(triazole)amine Complex Arises from Copper Impurities

Timothy U Connell, Christine Schieber, Ilaria Proietti Silvestri, Jonathan M White, Spencer J Williams, Paul S Donnelly

Journal article  |  2014  |  Inorganic Chemistry

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Oral Treatment with Cu-II(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Blaine R Roberts, Nastasia KH Lim, Erin J McAllum, Paul S Donnelly, Dominic J Hare, Philip A Doble, Bradley J Turner, Katherine A Price, Sin Chun Lim, Brett M Paterson, James L Hickey, Timothy W Rhoads, Jared R Williams, Katja M Kanninen, Lin W Hung, Jeffrey R Liddell, Alexandra Grubman, Jean-Francois Monty, Roxana M Llanos, David R Kramer, et al.

Journal article  |  2014  |  Journal of Neuroscience

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Enzyme-Mediated Site-Specific Bioconjugation of Metal Complexes to Proteins: Sortase-Mediated Coupling of Copper-64 to a Single-Chain Antibody

Brett M Paterson, Karen Alt, Charmaine M Jeffery, Roger I Price, Shweta Jagdale, Sheena Rigby, Charlotte C Williams, Karlheinz Peter, Christoph E Hagemeyer, Paul S Donnelly

Journal article  |  2014  |  Angewandte Chemie - International Edition

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Understanding Electrogenerated Chemiluminescence Efficiency in Blue-Shifted Iridium(III)-Complexes: An Experimental and Theoretical Study

Gregory J Barbante, Egan H Doeven, Emily Kerr, Timothy U Connell, Paul S Donnelly, Jonathan M White, Thais Lopes, Sarah Laird, David JD Wilson, Peter J Barnard, Conor F Hogan, Paul S Francis

Journal article  |  2014  |  Chemistry - A European Journal

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Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation

Laura Bica, Jeffrey R Liddell, Paul S Donnelly, Clare Duncan, Aphrodite Caragounis, Irene Volitakis, Brett M Paterson, Roberto Cappai, Alexandra Grubman, James Camakaris, Peter J Crouch, Anthony R White

Journal article  |  2014  |  PLoS ONE

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PET imaging of tumours with a Cu-64 labeled macrobicyclic cage amine ligand tethered to Tyr(3)-octreotate

Brett M Paterson, Peter Roselt, Delphine Denoyer, Carleen Cullinane, David Binns, Wayne Noonan, Charmaine M Jeffery, Roger I Price, Jonathan M White, Rodney J Hicks, Paul S Donnelly

Journal article  |  2014  |  Dalton Transactions

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Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

Karrera Y Djoko, Brett M Paterson, Paul S Donnelly, Alastair G McEwan

Journal article  |  2014  |  Metallomics: integrated biometal science

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X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder

A Grubman, SA James, J James, C Duncan, I Volitakis, JL Hickey, PJ Crouch, PS Donnelly, KM Kanninen, JR Liddell, SL Cotman, MD de Jonge, AR White

Journal article  |  2014  |  Chemical Science

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Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

Alexandra Grubman, Grace E Lidgerwood, Clare Duncan, Laura Bica, Jiang-Li Tan, Sarah J Parker, Aphrodite Caragounis, Jodi Meyerowitz, Irene Volitakis, Diane Moujalled, Jeffrey R Liddell, James L Hickey, Malcolm Horne, Shoshanah Longmuir, Jari Koistinaho, Paul S Donnelly, Peter J Crouch, Imke Tammen, Anthony R White, Katja M Kanninen

Journal article  |  2014  |  Acta Neuropathologica Communications

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Metal complexes designed to bind to amyloid-beta for the diagnosis and treatment of Alzheimer's disease

David J Hayne, SinChun Lim, Paul S Donnelly

Journal article  |  2014  |  Chem. Soc. Rev.

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Inhibition of respiratory Complex I by copper(II)-bis(thiosemicarbazonato) complexes

Karrera Y Djoko, Paul S Donnelly, Alastair G McEwan

Journal article  |  2014  |  Metallomics

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Role of the Metal, Ligand, and Alkyl/Aryl Group in the Hydrolysis Reactions of Group 10 Organometallic Cations [(L)M(R)]( )

Matthew J Woolley, George N Khairallah, Gabriel da Silva, Paul S Donnelly, Brian F Yates, Richard AJ O'Hair

Journal article  |  2013  |  Organometallics

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Therapeutic effects of Cu-II(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

Erin J McAllum, Nastasia K-H Lim, James L Hickey, Brett M Paterson, Paul S Donnelly, Qiao-Xin Li, Jeffrey R Liddell, Kevin J Barnham, Anthony R White, Peter J Crouch

Journal article  |  2013  |  Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

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Erratum: Copper modulates the large dense core vesicle secretory pathway in PC12 cells (Metallomics (2013) 5 (700-714) DOI:10.1039/C3MT20231C)

C Duncan, L Bica, PJ Crouch, A Caragounis, GE Lidgerwood, SJ Parker, J Meyerowitz, I Volitakis, JR Liddell, R Raghupathi, BM Paterson, MD Duffield, R Cappai, PS Donnelly, A Grubman, J Camakaris, DJ Keating, AR White

Journal article  |  2013  |  Metallomics

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Diagnostic Imaging Agents for Alzheimer's Disease: Copper Radiopharmaceuticals that Target A beta Plaques

James L Hickey, SinChun Lim, David J Hayne, Brett M Paterson, Jonathan M White, Victor L Villemagne, Peter Roselt, David Binns, Carleen Cullinane, Charmaine M Jeffery, Roger I Price, Kevin J Barnham, Paul S Donnelly

Journal article  |  2013  |  Journal of the American Chemical Society

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Synthesis, Structure and Gas-Phase Reactivity of a Silver Hydride Complex [Ag-3{(PPh2)(2)CH2}(3)(mu(3)-H)(mu(3)-Cl)]BF4

Athanasios Zavras, George N Khairallah, Timothy U Connell, Jonathan M White, Alison J Edwards, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2013  |  Angewandte Chemie - International Edition

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A Click Chemistry Approach to 5,5 '-Disubstituted-3,3 '-Bisisoxazoles from Dichloroglyoxime and Alkynes: Luminescent Organometallic Iridium and Rhenium Bisisoxazole Complexes

Phillip L van der Peet, Timothy U Connell, Christian Gunawan, Jonathan M White, Paul S Donnelly, Spencer J Williams

Journal article  |  2013  |  Journal of Organic Chemistry

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Increasing Intracellular Bioavailable Copper Selectively Targets Prostate Cancer Cells

Michael A Cater, Helen B Pearson, Kamil Wolyniec, Paul Klaver, Maree Bilandzic, Brett M Paterson, Ashley I Bush, Patrick O Humbert, Sharon La Fontaine, Paul S Donnelly, Ygal Haupt

Journal article  |  2013  |  ACS Chemical Biology

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Sarcophane bifunctional chelators: Effect of chelator charge on renal uptake

Jason LJ Dearling, Brett M Paterson, S Ted Treves, Stephan D Voss, Paul S Donnelly, Alan B Packard

Conference Proceedings  |  2013  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

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Increased Zinc and Manganese in Parallel with Neurodegeneration, Synaptic Protein Changes and Activation of Akt/GSK3 Signaling in Ovine CLN6 Neuronal Ceroid Lipofuscinosis

Katja M Kanninen, Alexandra Grubman, Jodi Meyerowitz, Clare Duncan, Jiang-Li Tan, Sarah J Parker, Peter J Crouch, Brett M Paterson, James L Hickey, Paul S Donnelly, Irene Volitakis, Imke Tammen, David N Palmer, Anthony R White

Journal article  |  2013  |  PLoS One

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Halide-ion-templated Ag8Cu6 rhombic dodecahedrons: synthesis, structure and reactivity of [Ag8Cu6(C=CtBu)(12)X]BF4 (X = Cl, Br)

Timothy U Connell, Saman Sandanayake, George N Khairallah, Jonathan M White, Richard AJ O'Hair, Paul S Donnelly, Spencer J Williams

Journal article  |  2013  |  Dalton Transactions

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Copper modulates the large dense core vesicle secretory pathway in PC12 cells

Clare Duncan, Laura Bica, Peter J Crouch, Aphrodite Caragounis, Grace E Lidgerwood, Sarah J Parker, Jodi Meyerowitz, Irene Volitakis, Jeffrey R Liddell, Ravinarayan Raghupathi, Brett M Paterson, Michael D Duffield, Roberto Cappai, Paul S Donnelly, Alexandra Grubman, James Camakaris, Damien J Keating, Anthony R White

Journal article  |  2013  |  Metallomics: integrated biometal science

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Rhenium and technetium tricarbonyl complexes of 1,4-substituted pyridyl-1,2,3-triazole bidentate ‘click’ ligands conjugated to a targeting RGD peptide

TU Connell, DJ Hayne, U Ackermenn, JM White, PS Donnelly, Henri TOCHON-DANGUY

Journal article  |  2013  |  Journal of Labelled Compounds and Radiopharmaceuticals

New 1,4‐substituted pyridyl‐1,2,3‐triazole ligands with pendent phenyl isothiocyanate functional groups linked to the heterocycle ..

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Interaction of cisplatin and analogue Pt(en)Cl-2 with the copper metallo-chaperone Atox1

Chak Ming Sze, Zhenyu Shi, George N Khairallah, Linda Feketeova, Richard AJ O'Hair, Zhiguang Xiao, Paul S Donnelly, Anthony G Wedd

Journal article  |  2013  |  Metallomics: integrated biometal science

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Copper modulates the large dense core vesicle secretory pathway in PC12 cells (vol 5, pg 700, 2013)

Clare Duncan, Laura Bica, Peter J Crouch, Aphrodite Caragounis, Grace E Lidgerwood, Sarah J Parker, Jodi Meyerowitz, Irene Volitakis, Jeffrey R Liddell, Ravinarayan Raghupathi, Brett M Paterson, Michael D Duffield, Roberto Cappai, Paul S Donnelly, Alexandra Grubman, James Camakaris, Damien J Keating, Anthony R White

Journal article  |  2013  |  METALLOMICS

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Diagnostic imaging of Alzheimer's disease with copper and technetium complexes

James L Hickey, Paul S Donnelly

Journal article  |  2012  |  Coordination Chemistry Reviews

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Inhibition of TDP-43 Accumulation by Bis(thiosemicarbazonato)-Copper Complexes

Sarah J Parker, Jodi Meyerowitz, Janine L James, Jeffrey R Liddell, Takashi Nonaka, Masato Hasegawa, Katja M Kanninen, SinChun Lim, Brett M Paterson, Paul S Donnelly, Peter J Crouch, Anthony R White

Journal article  |  2012  |  PLoS One

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Comparison of Cu-64-Complexing Bifunctional Chelators for Radioimmunoconjugation: Labeling Efficiency, Specific Activity, and in Vitro/in Vivo Stability

Maggie S Cooper, Michelle T Ma, Kavitha Sunassee, Karen P Shaw, Jennifer D Williams, Rowena L Paul, Paul S Donnelly, Philip J Blower

Journal article  |  2012  |  Bioconjugate Chemistry

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The hypoxia imaging agent Cu-II(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease

Lin W Hung, Victor L Villemagne, Lesley Cheng, Nicki A Sherratt, Scott Ayton, Anthony R White, Peter J Crouch, SinChun Lim, Su Ling Leong, Simon Wilkins, Jessica George, Blaine R Roberts, Chi LL Pham, Xiang Liu, Francis CK Chiu, David M Shackleford, Andrew K Powell, Colin L Masters, Ashley I Bush, Graeme O'Keefe, et al.

Journal article  |  2012  |  Journal of Experimental Medicine

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An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copper(II)

Paul S Donnelly, Jeffrey R Liddell, SinChun Lim, Brett M Paterson, Michael A Cater, Maria S Savva, Alexandra I Mot, Janine L James, Ian A Trounce, Anthony R White, Peter J Crouch

Journal article  |  2012  |  Proceedings of the National Academy of Sciences of the United States of America

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Conjugation of Transferrin to Azide-Modified CdSe/ZnS Core-Shell Quantum Dots using Cyclooctyne Click Chemistry

Christine Schieber, Alessandra Bestetti, Jet Phey Lim, Anneke D Ryan, Nguyen Tich-Lam, Robert Eldridge, Anthony R White, Paul A Gleeson, Paul S Donnelly, Spencer J Williams, Paul Mulvaney

Journal article  |  2012  |  Angewandte Chemie - International Edition

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The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells

Katherine A Price, James L Hickey, Zhiguang Xiao, Anthony G Wedd, Simon A James, Jeffrey R Liddell, Peter J Crouch, Anthony R White, Paul S Donnelly

Journal article  |  2012  |  Chemical Science

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Copper complexes of a novel non-innocent quadridentate ligand

Gojko Buncic, Zhiguang Xiao, Simon C Drew, Jonathan M White, Anthony G Wedd, Paul S Donnelly

Journal article  |  2012  |  Chemical Communications

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Diacetylbis(N(4)-methylthiosemicarbazonato) Copper(II) (Cu-II(atsm)) Protects against Peroxynitrite-induced Nitrosative Damage and Prolongs Survival in Amyotrophic Lateral Sclerosis Mouse Model

Cynthia PW Soon, Paul S Donnelly, Bradley J Turner, Lin W Hung, Peter J Crouch, Nicki A Sherratt, Jiang-Li Tan, Nastasia K-H Lim, Linh Lam, Laura Bica, SinChun Lim, James L Hickey, Julia Morizzi, Andrew Powell, David I Finkelstein, Janetta G Culvenor, Colin L Masters, James Duce, Anthony R White, Kevin J Barnham, et al.

Journal article  |  2011  |  Journal of Biological Chemistry

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Mechanisms Controlling the Cellular Accumulation of Copper Bis(thiosemicarbazonato) Complexes

Katherine Ann Price, Peter J Crouch, Irene Volitakis, Brett M Paterson, SinChun Lim, Paul S Donnelly, Anthony R White

Journal article  |  2011  |  Inorganic Chemistry

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Gallium-68 Complex of a Macrobicyclic Cage Amine Chelator Tethered to Two Integrin-Targeting Peptides for Diagnostic Tumor Imaging

Michelle T Ma, Oliver C Neels, Delphine Denoyer, Peter Roselt, John A Karas, Denis B Scanlon, Jonathan M White, Rodney J Hicks, Paul S Donnelly

Journal article  |  2011  |  Bioconjugate Chemistry

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The Alzheimer's therapeutic PBT2 promotes amyloid-beta degradation and GSK3 phosphorylation via a metal chaperone activity

Peter J Crouch, Maria S Savva, Lin W Hung, Paul S Donnelly, Alexandra I Mot, Sarah J Parker, Mark A Greenough, Irene Volitakis, Paul A Adlard, Robert A Cherny, Colin L Masters, Ashley I Bush, Kevin J Barnham, Anthony R White

Journal article  |  2011  |  Journal of Neurochemistry

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THE MECHANISM OF ACTION OF METAL-LIGAND COMPLEXES AS POTENTIAL THERAPEUTICS TO TREAT NEURODEGENERATIVE DISEASE

PJ Crouch, LW Hung, C Soon, PA Adlard, CL Masters, QX Li, PS Donnelly, KJ Barnham, AR White

Conference Proceedings  |  2011  |  JOURNAL OF NEUROCHEMISTRY

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Nitrogen adduction by three coordinate group 10 organometallic cations: platinum is favoured over nickel and palladium

Matthew J Woolley, George N Khairallah, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2011  |  Rapid Communications in Mass Spectrometry

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Macrobicyclic Cage Amine Ligands for Copper Radiopharmaceuticals: A Single Bivalent Cage Amine Containing Two Lys(3)-bombesin Targeting Peptides

Michelle T Ma, Margaret S Cooper, Rowena L Paul, Karen P Shaw, John A Karas, Denis Scanlon, Jonathan M White, Philip J Blower, Paul S Donnelly

Journal article  |  2011  |  Inorganic Chemistry

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Cellular Up-regulation of Nedd4 Family Interacting Protein 1 (Ndfip1) using Low Levels of Bioactive Cobalt Complexes

Christine Schieber, Jason Howitt, Ulrich Putz, Jonathan M White, Clare L Parish, Paul S Donnelly, Seong-Seng Tan

Journal article  |  2011  |  Journal of Biological Chemistry

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Metal Ionophore Treatment Restores Dendritic Spine Density and Synaptic Protein Levels in a Mouse Model of Alzheimer's Disease

Paul A Adlard, Laura Bica, Anthony R White, Milawaty Nurjono, Gulay Filiz, Peter J Crouch, Paul S Donnelly, Roberto Cappai, David I Finkelstein, Ashley I Bush

Journal article  |  2011  |  PLoS One

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Peptide Targeted Copper-64 Radiopharmaceuticals

Michelle T Ma, Paul S Donnelly

Journal article  |  2011  |  Current Topics in Medicinal Chemistry

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Cell cycle arrest in cultured neuroblastoma cells exposed to a bis(thiosemicarbazonato) metal complex

Laura Bica, Jodi Meyerowitz, Sarah J Parker, Aphrodite Caragounis, Tai Du, Brett M Paterson, Kevin J Barnham, Peter J Crouch, Anthony R White, Paul S Donnelly

Journal article  |  2011  |  Biometals

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Subcellular localization of a fluorescent derivative of Cu-II(atsm) offers insight into the neuroprotective action of Cu-II(atsm)

Katherine Ann Price, Peter J Crouch, SinChun Lim, Brett M Paterson, Jeffrey R Liddell, Paul S Donnelly, Anthony R White

Journal article  |  2011  |  Metallomics: integrated biometal science

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Copper complexes of bis(thiosemicarbazones): from chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals

Brett M Paterson, Paul S Donnelly

Journal article  |  2011  |  Chemical Society Reviews

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The role of coordination chemistry in the development of copper and rhenium radiopharmaceuticals

Paul S Donnelly

Journal article  |  2011  |  Dalton Transactions

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Copper(I)-catalyzed cycloaddition of silver acetylides and azides: Incorporation of volatile acetylenes into the triazole core

Ilaria Proietti Silvestri, Fikre Andemarian, George N Khairallah, Su Wan Yap, Tim Quach, Sammi Tsegay, Craig M Williams, Richard AJ O'Hair, Paul S Donnelly, Spencer J Williams

Journal article  |  2011  |  Organic & Biomolecular Chemistry

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Copper(II) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3 beta inhibition due to intracellular delivery of copper

James L Hickey, Peter J Crouch, Sithorn Mey, Aphrodite Caragounis, Jonathan M White, Anthony R White, Paul S Donnelly

Journal article  |  2011  |  Dalton Transactions

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Water-soluble Bis(thiosemicarbazonato)copper(II) Complexes

Gojko Buncic, James L Hickey, Christine Schieber, Jonathan M White, Peter J Crouch, Anthony R White, Zhiguang Xiao, Anthony G Wedd, Paul S Donnelly

Journal article  |  2011  |  Australian Journal of Chemistry

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A Water-Soluble Bis(thiosemicarbazone) Ligand. A Sensitive Probe and Metal Buffer for Zinc

Gojko Buncic, Paul S Donnelly, Brett M Paterson, Jonathan M White, Matthias Zimmermann, Zhiguang Xiao, Anthony G Wedd

Journal article  |  2010  |  Inorganic Chemistry

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Versatile New Bis(thiosemicarbazone) Bifunctional Chelators: Synthesis, Conjugation to Bombesin(7-14)-NH2, and Copper-64 Radiolabeling

Brett M Paterson, John A Karas, Denis B Scanlon, Jonathan M White, Paul S Donnelly

Journal article  |  2010  |  Inorganic Chemistry

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Copper and zinc bis(thiosemicarbazonato) complexes with a fluorescent tag: synthesis, radiolabelling with copper-64, cell uptake and fluorescence studies

SinChun Lim, Katherine A Price, Siow-Feng Chong, Brett M Paterson, Aphrodite Caragounis, Kevin J Barnham, Peter J Crouch, Josephine M Peach, Jonathan R Dilworth, Anthony R White, Paul S Donnelly

Journal article  |  2010  |  Journal of Biological Inorganic Chemistry

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Preparation of bis(thiosemicarbazone) derivatives and their metal complexes

PS Donnelly

Patent  |  2010

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A copper radiopharmaceutical for diagnostic imaging of Alzheimer's disease: a bis(thiosemicarbazonato)copper(II) complex that binds to amyloid-beta plaques

SinChun Lim, Brett M Paterson, Michelle T Fodero-Tavoletti, Graeme J O'Keefe, Roberto Cappai, Kevin J Barnham, Victor L Villemagne, Paul S Donnelly

Journal article  |  2010  |  Chemical Communications

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A hexadentate bis(thiosemicarbazonato) ligand: rhenium(V), iron(III) and cobalt(III) complexes

Brett M Paterson, Jonathan M White, Paul S Donnelly

Journal article  |  2010  |  Dalton Transactions

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Bis(thiosemicarbazonato) Cu-64 Complexes for Positron Emission Tomography Imaging of Alzheimer's Disease

Michelle T Fodero-Tavoletti, Victor L Villemagne, Brett M Paterson, Anthony R White, Qiao-Xin Li, James Camakaris, Graeme J O'Keefe, Roberto Cappai, Kevin J Barnham, Paul S Donnelly

Journal article  |  2010  |  Journal of Alzheimer's Disease

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Preparation of nitrogen-containing macrocyclic conjugates as radiopharmaceuticals

PS Donnelly, M MA, D Scanlon

Patent  |  2010

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Sustained Activation of Glial Cell Epidermal Growth Factor Receptor by Bis(thiosemicarbazonato) Metal Complexes Is Associated with Inhibition of Protein Tyrosine Phosphatase Activity

Katherine Ann Price, Aphrodite Caragounis, Brett M Paterson, Gulay Filiz, Irene Volitakis, Colin L Masters, Kevin J Barnham, Paul S Donnelly, Peter J Crouch, Anthony R White

Journal article  |  2009  |  Journal of Medicinal Chemistry

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MODULATING COPPER BIO-AVAILABILITY TO TREAT NEURODEGENERATIVE DISEASES

PJ Crouch, LW Hung, CP Soon, PA Adlard, A Bush, CL Masters, QX Li, PS Donnelly, KJ Barnham, AR White

Conference Proceedings  |  2009  |  JOURNAL OF NEUROCHEMISTRY

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Membrane-targeted strategies for modulating APP and A beta-mediated toxicity

Katherine A Price, Peter J Crouch, Paul S Donnelly, Colin L Masters, Anthony R White, Cyril C Curtain

Journal article  |  2009  |  Journal of Cellular and Molecular Medicine

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Interaction of cisplatin and analogues with a Met-rich protein site

Chak Ming Sze, George N Khairallah, Zhiguang Xiao, Paul S Donnelly, Richard AJ O'Hair, Anthony G Wedd

Journal article  |  2009  |  Journal of Biological Inorganic Chemistry

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Increasing Cu bioavailability inhibits A beta oligomers and tau phosphorylation

Peter J Crouch, Lin Wai Hung, Paul A Adlard, Mikhalina Cortes, Varsha Lal, Gulay Filiz, Keyla A Perez, Milawaty Nurjono, Aphrodite Caragounis, Tai Du, Katrina Laughton, Irene Volitakis, Ashley I Bush, Qiao-Xin Li, Colin L Masters, Roberto Cappai, Robert A Cherny, Paul S Donnelly, Anthony R White, Kevin J Barnham

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

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A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Michelle T Ma, John A Karas, Jonathan M White, Denis Scanlon, Paul S Donnelly

Journal article  |  2009  |  Chemical Communications

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Variations on a Cage Theme: Some Complexes of Bicyclic Polyamines as Supramolecular Synthons

Ian J Clark, Alessandra Crispini, Paul S Donnelly, Lutz M Engelhardt, Jack M Harrowfield, Seong-Hoon Jeong, Yang Kim, George A Koutsantonis, Young Hoon Lee, Nigel A Lengkeek, Mauro Mocerino, Gareth L Nealon, Mark I Ogden, Yu Chul Park, Claudio Pettinari, Lara Polanzan, Elisabeth Rukmini, Alan M Sargeson, BrianW Skelton, Alexandre N Sobolev, et al.

Journal article  |  2009  |  Australian Journal of Chemistry

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'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes

Paul S Donnelly, Shannon D Zanatta, Steven C Zammit, Jonathan M White, Spencer J Williams

Journal article  |  2008  |  Chemical Communications

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Transfer of copper between bis(thiosemicarbazone) ligands and intracellular copper-binding proteins. Insights into mechanisms of copper uptake and hypoxia selectivity

Zhiguang Xiao, Paul S Donnelly, Matthias Zimmermann, Anthony G Wedd

Journal article  |  2008  |  Inorganic Chemistry

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Selective intracellular release of copper and zinc ions from bis( thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide

Paul S Donnelly, Aphrodite Caragounis, Tai Du, Katrina M Laughton, Irene Volitakis, Robert A Cherny, Robyn A Sharples, Andrew F Hill, Qiao-Xin Li, Colin L Masters, Kevin J Barnham, Anthony R White

Journal article  |  2008  |  Journal of Biological Chemistry

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Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide

Katherine A Price, Gulay Filiz, Aphrodite Caragounis, Tai Du, Katrina M Laughton, Colin L Masters, Robyn A Sharples, Andrew F Hill, Qiao-Xin Li, Paul S Donnelly, Kevin J Barnham, Peter J Crouch, Anthony R White

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology

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Metal delivery agents and therapeutic uses of the same

K BARNHAM, P DONNELLY, A WHITE

Patent  |  2008

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Preparation of metal complexes for therapeutic uses

K BARNHAM, P DONNELLY, A WHITE

Patent  |  2008

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Copper and Alzheimer's disease

Paul S Donnelly, Zhiguang Xiao, Anthony G Wedd

Journal article  |  2007  |  Current Opinion in Chemical Biology

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Functionalized bis(thiosemicarbazonato) complexes of zinc and copper: Synthetic platforms toward site-specific radiopharmaceuticals

Jason P Holland, Franklin I Aigbirhio, Helen M Betts, Paul D Bonnitcha, Paul Burke, Martin Christlieb, Grant C Churchill, Andrew R Cowley, Jonathan R Dilworth, Paul S Donnelly, Jennifer C Green, Josephine M Peach, Sridhar R Vasudevan, John E Warren

Journal article  |  2007  |  Inorganic Chemistry

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Rhenium diazenide ternary complexes with dithiocarbamate ligands: towards new rhenium radiopharmaceuticals

Andrew R Cowley, Jonathan R Dilworth, Paul S Donnelly, Susan J Ross

Journal article  |  2007  |  Dalton Transactions

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Copper and zinc bis(thiosemicarbazonato) complexes for the treatment of Alzheimer's disease

P DONNELLY, K BARNHAM, A WHITE

Journal article  |  2007  |  Journal of Biological Inorganic Chemistry

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Bifunctional chelators for copper radiopharmaceuticals: the synthesis of [Cu(ATSM)-amino acid] and [Cu(ATSM)-octreotide] conjugates

Andrew R Cowley, Jonathan R Dilworth, Paul S Donnelly, Julia M Heslop, Steven J Ratcliffe

Journal article  |  2007  |  Dalton Transactions

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Alzheimer's disease and the chemistry of copper

P DONNELLY, A WEDD

Journal article  |  2007  |  Chemistry in Australia

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Preparation of transition metal thiosemicarbazone derivative complexes for medical imaging and therapy

R Dilworth, M Peach, M Heslop, P DONNELLY

Patent  |  2007

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New bimetallic compounds based on the bis(thiosemicarbazonato) motif

Martin Christlieb, Andrew R Cowley, Jonathan R Dilworth, Paul S Donnelly, Brett M Paterson, Harriet SR Struthersa, Jonathan M White

Journal article  |  2007  |  Dalton Transactions

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Copper complexes of thiosemicarbazone-pyridylhydrazine (THYNIC) hybrid ligands: A new versatile potential bifunctional chelator for copper radiopharmaceuticals

AR Cowley, JR Dilworth, PS Donnelly, JM White

Journal article  |  2006  |  Inorganic Chemistry

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75Re Therapeutic Rhenium Radiopharmaceuticals

JR Dilworth, PS Donnelly

Book Chapter  |  2005

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Investigations into some aryl substituted bis(thiosemicarbazones) and their copper complexes

L Alsop, AR Cowley, JR Dilworth, PS Donnelly, JM Peach, JT Rider

Journal article  |  2005  |  Inorganica Chimica Acta

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Fluorescence studies of the intra-cellular distribution of zinc bis(thiosemicarbazone) complexes in human cancer cells

AR Cowley, JJ Davis, JR Dilworth, PS Donnelly, R Dobson, A Nightingale, JM Peach, B Shore, D Kerr, L Seymour

Journal article  |  2005  |  Chemical Communications

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Method of Treatment of Neurodegenerative Disease

PS DONNELLY, T WHITE, KJ BARNHAM

Patent  |  2005

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Radiosynthesis of novel copper(II) bis(thiosemicarbazones) PET tracers

P DONNELLY, undefined Golovko, M Heslop, undefined Burke, C Clark, I Aigbirhio

Journal article  |  2005  |  Journal of Labelled Compounds & Radiopharmaceuticals

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Therapeutic rhenium radiopharmaceuticals

R Dilworth, P DONNELLY

Book Chapter  |  2005

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Functionalized thiosemicarbazone clusters of copper(I) and silver(I)

LJ Ashfield, AR Cowley, JR Dilworth, PS Donnelly

Journal article  |  2004  |  Inorganic Chemistry

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Diazenide and hydrazide(2-) derivatives of the [Re(CO)(3)]( ) core

R Alberto, AR Cowley, JR Dilworth, PS Donnelly, J Pratt

Journal article  |  2004  |  Dalton Transactions

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Acetylacetonate bis(thiosemicarbazone) complexes of copper and nickel: towards new copper radiopharmaceuticals

AR Cowley, JR Dilworth, PS Donnelly, AD Gee, JM Heslop

Journal article  |  2004  |  Dalton Transactions

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Pyridylthiocarbazide complexes of rhenium with potential radiopharmaceutical applications

C Clarke, AR Cowley, JR Dilworth, PS Donnelly

Journal article  |  2004  |  Dalton Transactions

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A mono-diazenide complex from perrhenate: Toward a new core for rhenium radiopharmaceuticals

AR Cowley, JR Dilworth, PS Donnelly

Journal article  |  2003  |  Inorganic Chemistry

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Synthesis and characterisation of new homoleptic rhenium thiosemicarbazone complexes

AR Cowley, JR Dilworth, PS Donnelly, J Woollard-Shore

Journal article  |  2003  |  Dalton Transactions

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'Neutralmolekulcomplexe' - Structural characterization of some adducts of urea and thiourea with N,N '-bidentate aromatic bases

PS Donnelly, BW Skelton, AH White

Journal article  |  2003  |  Australian Journal of Chemistry

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Structural trends in copper(II) bis(thiosemicarbazone) radiopharmaceuticals

PJ Blower, TC Castle, AR Cowley, JR Dilworth, PS Donnelly, E Labisbal, FE Sowrey, SJ Teat, MJ Went

Journal article  |  2003  |  Dalton Transactions

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An unusual dimeric structure of a Cu(I) bis(thiosemicarbazone) complex: Implications for the mechanism of hypoxic selectivity of the Cu(II) derivatives

AR Cowley, JR Dilworth, PS Donnelly, E Labisbal, A Sousa

Journal article  |  2002  |  Journal of the American Chemical Society

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Towards Rhenium Radiopharmaceuticals with Diazenide and Dithiocarbamate Ligands

R Cowley, R Dilworth, S Donnelly, J Ross

Book Chapter  |  2002

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Towards New Copper and Rhenium Based Radiopharmaceuticals

J Ashfield, undefined Carole, R Cowley, R Dilworth, S Donnelly, M Heslop

Book Chapter  |  2002

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Synthesis with coordinated ligands: biomolecule attachment to cage amines

PS Donnelly, JM Harrowfield

Journal article  |  2002  |  Journal of the Chemical Society - Dalton Transactions

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Chirality in coordination polymers: Homo- vs. hetero-chiral strand construction

PS Donnelly, JM Harrowfield, BW Skelton, AH White

Journal article  |  2001  |  Journal of the Chemical Society, Dalton Transactions

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Carboxymethylated cage amines: Coordination and lactamization

PS Donnelly, JM Harrowfield, BW Skelton, AH White

Journal article  |  2001  |  Inorganic Chemistry

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Functionalization of cage amines with pendant aromatic and heteroaromatic substituents

S Burnet, MH Choi, PS Donnelly, JM Harrowfield, I Ivanova, SH Jeong, Y Kim, M Mocerino, BW Skelton, AH White, CC Williams, ZL Zeng

Journal article  |  2001  |  European Journal of Inorganic Chemistry

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Chirality in coordination polymers: homo- vs. hetero-chiral strand construction

PS Donnelly, JM Harrowfield, BW Skelton, AH White

Journal article  |  2001  |  Journal of the Chemical Society - Dalton Transactions

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An octapositive cation incorporating multiple redox centres: Cage amine complexes of cobalt(III) linked by a 2,2 '-bis(pyridinium) unit

PS Donnelly, JM Harrowfield, BW Skelton, AH White

Journal article  |  2001  |  Australian Journal of Chemistry

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Carboxymethylation of cage amines: control of alkylation by metal ion coordination.

PS Donnelly, JM Harrowfield, BW Skelton, AH White

Journal article  |  2000  |  Inorganic Chemistry

Reactions between chloroacetate and both "free" and coordinated forms of the cage amine diaminosarcophagine (1,8-diamino-3,6,10,13..

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Scholarly Works

Keyword Analysis

Inorganic Chemistry
Expanding Knowledge
Non-Oriented Research
Organic Chemistry
Medicinal and Biomolecular Chemistry
Clinical Health (organs, Diseases and Abnormal Conditions)
Neurosciences
Physical Chemistry (incl. Structural)
Other Chemical Sciences
Biochemistry and Cell Biology

News

Displaying the 2 most recent news articles by Paul Donnelly.

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Surgeons go green: Recycling general anaesthetic

Richard Robson, Paul Donnelly, Brendan Abrahams

August 9, 2017
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Breakthrough in motor neurone disease research gives hope

Kevin Barnham, Paul Donnelly, Anthony White

January 17, 2017

2

News Articles

Honours, Awards and Fellowships

2016

David Syme Research Prize

University of Melbourne
2014

Grimwade Prize in Industrial Chemistry

University of Melbourne
2013

Future Fellowship

Australian Research Council
2012

Dean's Award for Excellence in Research

University of Melbourne, Faculty of Science
2012

Young Investigator Award

Gordon Research Conference: Metals in Medicine
2011

Biota Award for Medicinal Chemistry

Royal Australian Chemical Institute
2010

Rennie Memorial Medal (2010)

Royal Australian Chemical Institute
2008

Alan Sargeson Lectureship

Royal Australian Chemical Institute
2007

Selby Research Award 2007

University of Melbourne
2005

Kaye Merlin Brutton Prize

University of Melbourne
2005

Patent Support Grant

University of Melbourne
2004

Postdoctoral Research Fellowship

Australian Research Council Australian
2004

Fulford Junior Research Fellowship

Somerville College, University of Oxford
2004

Annual Merit Award

University of Oxford
2003

Annual Merit Award

University of Oxford

15

Awards

Credentials

Positions

Professor In Chemistry

Chemistry

Member

American Chemical Society

Member

Society of Biological Inorganic Chemistry

Mraci Cchem

Royal Australian Chemical Institute

Education

Doctor of Philosophy

The University of Western Australia

Bachelor of Science (honours)

The University of Western Australia

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