Katherine Kedzierska

A Dual-Antigen Enzyme-Linked Immunosorbent Assay Allows the Assessment of Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Seroprevalence in a Low-Transmission Setting.

Sarah M Hicks, Kai Pohl, Teresa Neeman, Hayley A McNamara, Kate M Parsons, Jin-Shu He, Sidra A Ali, Samina Nazir, Louise C Rowntree, Thi HO Nguyen, Katherine Kedzierska, Denise L Doolan, Carola G Vinuesa, Matthew C Cook, Nicholas Coatsworth, Paul S Myles, Florian Kurth, Leif E Sander, Graham J Mann, Russell L Gruen, et al.

Journal article  |  2021  |  Journal of Infectious Diseases

Estimates of seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies have been hampered by inade..

Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19

Shidan Tosif, Melanie R Neeland, Philip Sutton, Paul V Licciardi, Sohinee Sarkar, Kevin J Selva, Anh Ha Do Lien, Celeste Donato, Zheng Quan Toh, Rachel Higgins, Carolien Van de Sandt, Melissa M Lemke, Christina Y Lee, Suzanne K Shoffner, Katie L Flanagan, Kelly B Arnold, Francesca L Mordant, Kim Mulholland, Julie Bines, Kate Dohle, et al.

Journal article  |  2020  |  Nature Communications

Compared to adults, children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have predominantly mild or asymptom..

Viral burden, inflammatory milieu and CD8( )T-cell responses to influenza virus in a second-generation thiazolide (RM-5061) and oseltamivir combination therapy study

Simone Nuessing, Edin Mifsud, Luca Hensen, Marios Koutsakos, Zhongfang Wang, Lukasz Kedzierski, Francesca Mercuri, Jean-Francois Rossignol, Aeron C Hurt, Katherine Kedzierska

Journal article  |  2020  |  Influenza and Other Respiratory Viruses

BACKGROUND: Influenza viruses cause significant morbidity and mortality, especially in young children, elderly, pregnant women and..

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Simone Nüssing, Edin Mifsud, Luca Hensen, Marios Koutsakos, Zhongfang Wang, Lukasz Kedzierski, Francesca Mercuri, Jean‐Francois Rossignol, Aeron C Hurt, Katherine Kedzierska

Journal article  |  2020  |  Influenza and Other Respiratory Viruses

Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes

James G Bedford, Melanie Heinlein, Alexandra L Garnham, Thi HO Nguyen, Tom Loudovaris, Chenghao Ge, Stuart Mannering, Michael Elliott, Stuart G Tangye, Katherine Kedzierska, Daniel HD Gray, William R Heath, Linda M Wakim

Journal article  |  2020  |  Science Immunology

The nasal-associated lymphoid tissues (NALTs) are mucosal-associated lymphoid organs embedded in the submucosa of the nasal passag..

Suboptimal SARS-CoV-2-specific CD8( ) T cell response associated with the prominent HLA-A*02:01 phenotype

Jennifer R Habel, Thi HO Nguyen, Carolien E van de Sandt, Jennifer A Juno, Priyanka Chaurasia, Kathleen Wragg, Marios Koutsakos, Luca Hensen, Xiaoxiao Jia, Brendon Chua, Wuji Zhang, Hyon-Xhi Tan, Katie L Flanagan, Denise L Doolan, Joseph Torresi, Weisan Chen, Linda M Wakim, Allen C Cheng, Peter C Doherty, Jan Petersen, et al.

Journal article  |  2020  |  Proceedings of the National Academy of Sciences of USA

An improved understanding of human T cell-mediated immunity in COVID-19 is important for optimizing therapeutic and vaccine strate..

The Dynamics of the Ferret Immune Response During H7N9 Influenza Virus Infection

William SJ Horman, Thi HO Nguyen, Katherine Kedzierska, Jeffrey Butler, Songhua Shan, Rachel Layton, John Bingham, Jean Payne, Andrew GD Bean, Daniel S Layton

Journal article  |  2020  |  Frontiers in Immunology

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals

Louise C Rowntree, Thi HO Nguyen, Carine Farenc, Hanim Halim, Luca Hensen, Jamie Rossjohn, Tom C Kotsimbos, Anthony W Purcell, Katherine Kedzierska, Stephanie Gras, Nicole A Mifsud

Journal article  |  2020  |  The Journal of Immunology

EBV is one of the most common viruses found in humans and is prototypic of a persistent viral infection characterized by periods o..

Immune profiling of influenza-specific B- and T-cell responses in macaques using flow cytometry-based assays

Marios Koutsakos, Toshiki Sekiya, Brendon Y Chua, Hoang Oanh Nguyen Thi, Adam K Wheatley, Jennifer A Juno, Marumi Ohno, Naoki Nomura, Yuki Ohara, Tomohiro Nishimura, Masafumi Endo, Saori Suzuki, Hirohito Ishigaki, Misako Nakayama, Cong T Nguyen, Yasushi Itoh, Masashi Shingai, Kazumasa Ogasawara, Yoichiro Kino, Stephen J Kent, et al.

Journal article  |  2020  |  Immunology and Cell Biology

Influenza remains a significant global public health burden, despite substantial annual vaccination efforts against circulating vi..

Innate and adaptive immunity toward influenza B viruses

Luca Hensen, Katherine Kedzierska, Marios Koutsakos

Journal article  |  2020  |  Future Microbiology

Despite annual vaccination, influenza B viruses (IBV) cause significant disease with substantial health and socio-economic impacts..