Katrina Binger

NCX1 represents an ionic Na sensing mechanism in macrophages.

Patrick Neubert, Arne Homann, David Wendelborn, Anna-Lorena Bär, Luka Krampert, Maximilian Trum, Agnes Schröder, Stefan Ebner, Andrea Weichselbaum, Valentin Schatz, Peter Linz, Roland Veelken, Jonas Schulte-Schrepping, Anna C Aschenbrenner, Thomas Quast, Christian Kurts, Sabrina Geisberger, Karl Kunzelmann, Karin Hammer, Katrina J Binger, et al.

Journal article  |  2020  |  PLOS Biology

Inflammation and infection can trigger local tissue Na+ accumulation. This Na+-rich environment boosts proinflammatory activation ..

Tetraspanin CD53 Promotes Lymphocyte Recirculation by Stabilizing L-Selectin Surface Expression

MC Demaria, L Yeung, R Peeters, JL Wee, M Mihaljcic, EL Jones, Z Nasa, F Alderuccio, P Hall, BC Smith, KJ Binger, G Hammerling, HF Kwok, A Newman, A Ager, A van Spriel, MJ Hickey, MD Wright

Journal article  |  2020  |  iScience

The amalgamation of cellular metabolism and immunology for host immunity

Justine D Mintern, Katrina J Binger

Journal article  |  2020  |  Clinical & Translational Immunology

Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic beta cells

Katrina J Binger, Martin Neukam, Sudhir Gopal Tattikota, Fatimunnisa Qadri, Dmytro Puchkov, Diana M Willmes, Sabrina Wurmsee, Sabrina Geisberger, Ralf Dechend, Klemens Raile, Thomas Kurth, Genevieve Nguyen, Matthew N Poy, Michele Solimena, Dominik N Muller, Andreas L Birkenfeld

Journal article  |  2019  |  Proceedings of the National Academy of Sciences

Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages

David P De Souza, Adrian Achuthan, Man KS Lee, Katrina J Binger, Ming-Chin Lee, Sophia Davidson, Dedreia L Tull, Malcolm J McConville, Andrew D Cook, Andrew J Murphy, John A Hamilton, Andrew J Fleetwood

Journal article  |  2019  |  Journal of Clinical Investigation

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8( ) T Cells

Annabel Bachem, Christina Makhlouf, Katrina J Binger, David P de Souza, Deidra Tull, Katharina Hochheiser, Paul G Whitney, Daniel Fernandez-Ruiz, Sabrina Dahling, Wolfgang Kastemuller, Johanna Jonsson, Elise Gressier, Andrew M Lew, Carolina Perdomo, Andreas Kupz, William Figgett, Fabienne Mackay, Moshe Oleshansky, Brendan E Russ, Ian A Parish, et al.

Journal article  |  2019  |  Immunity

Interactions with the microbiota influence many aspects of immunity, including immune cell development, differentiation, and funct..

HIF1A and NFAT5 coordinate Na -boosted antibacterial defense via enhanced autophagy and autolysosomal targeting

Patrick Neubert, Andrea Weichselbaum, Carmen Reitinger, Valentin Schatz, Agnes Schroeder, John R Ferdinand, Michaela Simon, Anna-Lorena Baer, Christoph Brochhausen, Roman G Gerlach, Stefan Tomiuk, Karin Hammer, Stefan Wagner, Ger van Zandbergen, Katrina J Binger, Dominik N Mueller, Kento Kitada, Menna R Clatworthy, Christian Kurts, Jens Titze, et al.

Journal article  |  2019  |  Autophagy

Macrophage heterogeneity and renin-angiotensin system disorders

Mark D Wright, Katrina J Binger

Journal article  |  2017  |  PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Immunometabolic Regulation of Interleukin-17-Producing T Helper Cells: Uncoupling New Targets for Autoimmunity

Katrina J Binger, Beatriz F Corte-Real, Markus Kleinewietfeld

Journal article  |  2017  |  Frontiers in Immunology

Elementary immunology: Na as a regulator of immunity

Valentin Schatz, Patrick Neubert, Agnes Schroeder, Katrina Binger, Matthias Gebhard, Dominik N Mueller, Friedrich C Luft, Jens Titze, Jonathan Jantsch

Journal article  |  2017  |  Pediatric Nephrology

High salt reduces the activation of IL-4-and IL-13-stimulated macrophages

Katrina J Binger, Matthias Gebhardt, Matthias Heinig, Carola Rintisch, Agnes Schroeder, Wolfgang Neuhofer, Karl Hilgers, Arndt Manzel, Christian Schwartz, Markus Kleinewietfeld, Jakob Voelkl, Valentin Schatz, Ralf A Linker, Florian Lang, David Voehringer, Mark D Wright, Norbert Hubner, Ralf Dechend, Jonathan Jantsch, Jens Titze, et al.

Journal article  |  2015  |  Journal of Clinical Investigation

New role for the (pro)renin receptor in T-cell development

Sabrina Geisberger, Ulrike Maschke, Matthias Gebhardt, Markus Kleinewietfeld, Arndt Manzel, Ralf A Linker, Ann Chidgey, Ralf Dechend, Genevieve Nguyen, Oliver Daumke, Dominik N Muller, Mark D Wright, Katrina J Binger

Journal article  |  2015  |  Blood

Cutaneous Na Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense

Jonathan Jantsch, Valentin Schatz, Diana Friedrich, Agnes Schroeder, Christoph Kopp, Isabel Siegert, Andreas Maronna, David Wendelborn, Peter Linz, Katrina J Binger, Matthias Gebhardt, Matthias Heinig, Patrick Neubert, Fabian Fischer, Stefan Teufel, Jean-Pierre David, Clemens Neufert, Alexander Cavallaro, Natalia Rakova, Christoph Kueper, et al.

Journal article  |  2015  |  Cell Metabolism

Sodium chloride, SGK1, and Th17 activation

Katrina J Binger, Ralf A Linker, Dominik N Muller, Markus Kleinewietfeld

Journal article  |  2015  |  Pflügers Archiv - European Journal of Physiology

Bcl10 Mediates Angiotensin II-Induced Cardiac Damage and Electrical Remodeling

Lajos Marko, Norbert Henke, Joon-Keun Park, Bastian Spallek, Fatimunnisa Qadri, Andras Balogh, Ingrid J Apel, Katherine I Oravecz-Wilson, Mira Choi, Lukasz Przybyl, Katrina J Binger, Nadine Haase, Nicola Wilck, Arnd Heuser, Verena Fokuhl, Juergen Ruland, Peter C Lucas, Linda M McAllister-Lucas, Friedrich C Luft, Ralf Dechend, et al.

Journal article  |  2014  |  Hypertension

Macrophages in homeostatic immune function

Jonathan Jantsch, Katrina J Binger, Dominik N Mueller, Jens Titze

Journal article  |  2014  |  Frontiers in Physiology

Autophagy and the (Pro)renin Receptor.

Katrina J Binger, Dominik N Muller

Journal article  |  2013  |  Frontiers in Endocrinology

The (pro)renin receptor (PRR) is a newly reported member of the renin-angiotensin system (RAS); a hormonal cascade responsible for..

Avoiding the oligomeric state: alpha B-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils

Katrina J Binger, Heath Ecroyd, Shuo Yang, John A Carver, Geoffrey J Howlett, Michael DW Griffin

Journal article  |  2013  |  FASEB Journal

Interferon-gamma Signaling Inhibition Ameliorates Angiotensin II-Induced Cardiac Damage

Lajos Marko, Heda Kvakan, Joon-Keun Park, Fatimunnisa Qadri, Bastian Spallek, Katrina J Binger, Edward P Bowman, Markus Kleinewietfeld, Verena Fokuhl, Ralf Dechend, Dominik N Mueller

Journal article  |  2012  |  Hypertension

An Equilibrium Model for Linear and Closed-Loop Amyloid Fibril Formation

Shuo Yang, Michael DW Griffin, Katrina J Binger, Peter Schuck, Geoffrey J Howlett

Journal article  |  2012  |  Journal of Molecular Biology

Identification of an amyloid fibril forming peptide comprising residues 46-59 of apolipoprotein A-I

Yuan Qi Wong, Katrina J Binger, Geoffrey J Howlett, Michael DW Griffin

Journal article  |  2012  |  FEBS Letters

Prorenin receptor regulates more than the renin-angiotensin system

Dominik N Mueller, Katrina J Binger, Fabian Riediger

Journal article  |  2012  |  Annals of Medicine

Neovascularization Is Attenuated With Aldosterone Synthase Inhibition in Rats With Retinopathy

Devy Deliyanti, Antonia G Miller, Genevieve Tan, Katrina J Binger, Andre L Samson, Jennifer L Wilkinson-Berka

Journal article  |  2012  |  Hypertension

Aliskiren reduces vascular pathology in diabetic retinopathy and oxygen-induced retinopathy in the transgenic (mRen-2)27 rat

JL Wilkinson-Berka, G Tan, KJ Binger, L Sutton, K McMaster, D Deliyanti, G Perera, DJ Campbell, AG Miller

Journal article  |  2011  |  Diabetologia

A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations

Chai Lean Teoh, Chi LL Pham, Nevena Todorova, Andrew Hung, Craig N Lincoln, Emma Lees, Yuen Han Lam, Katrina J Binger, Neil H Thomson, Sheena E Radford, Trevor A Smith, Shirley A Mueller, Andreas Engel, Michael DW Griffin, Irene Yarovsky, Paul R Gooley, Geoffrey J Howlett

Journal article  |  2011  |  Journal of Molecular Biology

Prorenin and the (pro)renin receptor: recent advances and implications for retinal development and disease

Jennifer L Wilkinson-Berka, Antonia G Miller, Katrina J Binger

Journal article  |  2011  |  Current Opinion in Nephrology and Hypertension

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

Antonia G Miller, Genevieve Tan, Katrina J Binger, Raelene J Pickering, Merlin C Thomas, Ram H Nagaraj, Mark E Cooper, Jennifer L Wilkinson-Berka

Journal article  |  2010  |  Diabetes

RILLKKMPSV Influences the Vasculature, Neurons and Glia, and (Pro)Renin Receptor Expression in the Retina

Jennifer L Wilkinson-Berka, Ronen Heine, Genevieve Tan, Mark E Cooper, Kate M Hatzopoulos, Erica L Fletcher, Katrina J Binger, Duncan J Campbell, Antonia G Miller

Journal article  |  2010  |  Hypertension

Methionine-Oxidized Amyloid Fibrils Are Poor Substrates for Human Methionine Sulfoxide Reductases A and B2

Katrina J Binger, Michael DW Griffin, Stefan H Heinemann, Geoffrey J Howlett

Journal article  |  2010  |  Biochemistry

Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein A-I

Yuan Qi Wong, Katrina J Binger, Geoffrey J Howlett, Michael DW Griffin

Journal article  |  2010  |  Proceedings of the National Academy of Sciences of the United States of America

Effect of Oxidation and Mutation on the Conformational Dynamics and Fibril Assembly of Amyloidogenic Peptides Derived from Apolipoprotein C-II

FS Legge, KJ Binger, MDW Griffin, GJ Howlett, D Scanlon, H Treutlein, I Yarovsky

Journal article  |  2009  |  Journal of Physical Chemistry B

Methionine oxidation inhibits assembly and promotes disassembly of apolipoprotein C-II amyloid fibrils

Katrina J Binger, Michael DW Griffin, Geoffrey J Howlett

Journal article  |  2008  |  Biochemistry

Apolipoprotein C-II amyloid fibrils assemble via a reversible pathway that includes fibril breaking and rejoining

Katrina J Binger, Chi LL Pham, Leanne M Wilson, Michael F Bailey, Lynne J Lawrence, Peter Schuck, Geoffrey J Howlett

Journal article  |  2008  |  Journal of Molecular Biology

A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis

Leanne M Wilson, Yee-Foong Mok, Katrina J Binger, Michael DW Griffin, Haydyn DT Mertens, Feng Lin, John D Wade, Paul R Gooley, Geoffrey J Howlett

Journal article  |  2007  |  Journal of Molecular Biology