Bridie Clemens

Challenging immunodominance of influenza-specific CD8( ) T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

CE van de Sandt, EB Clemens, EJ Grant, LC Rowntree, S Sant, H Halim, J Crowe, AC Cheng, TC Kotsimbos, M Richards, A Miller, SYC Tong, J Rossjohn, THO Nguyen, S Gras, W Chen, K Kedzierska

Journal article  |  2019  |  Nature Communications

Although influenza viruses lead to severe illness in high-risk populations, host genetic factors associated with severe disease ar..

TCF-1 limits the formation of Tc17 cells via repression of the MAF-ROR gamma t axis

Lisa A Mielke, Yang Liao, Ella Bridie Clemens, Matthew A Firth, Brigette Duckworth, Qiutong Huang, Francisca F Almeida, Michael Chopin, Hui-Fern Koay, Carolyn A Bell, Soroor Hediyeh-Zadeh, Simone L Park, Dinesh Raghu, Jarny Choi, Tracy L Putoczki, Philip D Hodgkin, Ashley E Franks, Laura K Mackay, Dale Godfrey, Melissa J Davis, et al.

Journal article  |  2019  |  Journal of Experimental Medicine

Divergent SATB1 expression across human life span and tissue compartments

Simone Nussing, Hui-Fern Koay, Sneha Sant, Thomas Loudovaris, Stuart I Mannering, Martha Lappas, Yves d'Udekem, Igor E Konstantinov, Stuart P Berzins, Guus F Rimmelzwaan, Stephen J Turner, E Bridie Clemens, Dale I Godfrey, HO Nguyen Thi, Katherine Kedzierska

Journal article  |  2019  |  Immunology & Cell Biology

Human CD8( ) T cell cross-reactivity across influenza A, B and C viruses

Marios Koutsakos, Patricia T Illing, Thi HO Nguyen, Nicole A Mifsud, Jeremy Chase Crawford, Simone Rizzetto, Auda A Eltahla, E Bridie Clemens, Sneha Sant, Brendon Y Chua, Chinn Yi Wong, E Kaitlynn Allen, Don Teng, Pradyot Dash, David F Boyd, Ludivine Grzelak, Weiguang Zeng, Aeron C Hurt, Ian Barr, Steve Rockman, et al.

Journal article  |  2019  |  Nature Immunology

Multiplex Droplet Digital PCR Assay for Quantification of Human T-Cell Leukemia Virus Type 1 Subtype c DNA Proviral Load and T Cells from Blood and Respiratory Exudates Sampled in a Remote Setting

David Yurick, Georges Khoury, Bridle Clemens, Liyen Loh, Hai Pham, Katherine Kedzierska, Lloyd Einsiedel, Damian Purcell

Journal article  |  2019  |  Journal of Clinical Microbiology

Broad CD8( ) T cell cross-recognition of distinct influenza A strains in humans

Emma J Grant, Tracy M Josephs, Liyen Loh, E Bridie Clemens, Sneha Sant, Mandvi Bharadwaj, Weisan Chen, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska

Journal article  |  2018  |  NATURE COMMUNICATIONS

Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

E Bridie Clemens, Carolien van de Sandt, Sook San Wong, Linda M Wakim, Sophie A Valkenburg

Journal article  |  2018  |  VACCINES

Clonally diverse CD38( )HLA-DR( )CD8( ) T cells persist during fatal H7N9 disease

Zhongfang Wang, Lingyan Zhu, Thi HO Nguyen, Yanmin Wan, Sneha Sant, Sergio M Quinones-Parra, Jeremy Chase Crawford, Auda A Eltahla, Simone Rizzetto, Rowena A Bull, Chenli Qiu, Marios Koutsakos, E Bridie Clemens, Liyen Loh, Tianyue Chen, Lu Liu, Pengxing Cao, Yanqin Ren, Lukasz Kedzierski, Tom Kotsimbos, et al.

Journal article  |  2018  |  NATURE COMMUNICATIONS

Circulating T-FH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity

Marios Koutsakos, Adam K Wheatley, Liyen Loh, E Bridie Clemens, Sneha Sant, Simone Nussing, Annette Fox, Amy W Chung, Karen L Laurie, Aeron C Hurt, Steve Rockman, Martha Lappas, Thomas Loudovaris, Stuart I Mannering, Glen P Westall, Michael Elliot, Stuart G Tangye, Linda M Wakim, Stephen J Kent, Thi HO Nguyen, et al.

Journal article  |  2018  |  SCIENCE TRANSLATIONAL MEDICINE

Perturbed CD8( ) T cell immunity across universal influenza epitopes in the elderly

Thi HO Nguyen, Sneha Sant, Nicola L Bird, Emma J Grant, E Bridie Clemens, Marios Koutsakos, Sophie A Valkenburg, Stephanie Gras, Martha Lappas, Anthony Jaworowski, Jane Crowe, Liyen Loh, Katherine Kedzierska

Journal article  |  2018  |  JOURNAL OF LEUKOCYTE BIOLOGY

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

Mikhail Shugay, Dmitriy V Bagaev, Ivan V Zvyagin, Renske M Vroomans, Jeremy Chase Crawford, Garry Dolton, Ekaterina A Komech, Anastasiya L Sycheva, Anna E Koneva, Evgeniy S Egorov, Alexey V Eliseev, Ewald Van Dyk, Pradyot Dash, Meriem Attaf, Cristina Rius, Kristin Ladell, James E McLaren, Katherine K Matthews, E Bridie Clemens, Daniel C Douek, et al.

Journal article  |  2018  |  NUCLEIC ACIDS RESEARCH

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Stephen W Scally, Soi-Cheng Law, Yi Tian Ting, Jurgen van Heemst, Jeremy Sokolove, Aaron J Deutsch, E Bridie Clemens, Antonis K Moustakas, George K Papadopoulos, Diane van der Woude, Irene Smolik, Carol A Hitchon, David B Robinson, Elizabeth D Ferucci, Charles N Bernstein, Xiaobo Meng, Vidyanand Anaparti, Tom Huizinga, Katherine Kedzierska, Hugh H Reid, et al.

Journal article  |  2017  |  Annals of the Rheumatic Diseases

Quantifiable predictive features define epitope-specific T cell receptor repertoires

Pradyot Dash, Andrew J Fiore-Gartland, Tomer Hertz, George C Wang, Shalini Sharma, Aisha Souquette, Jeremy Chase Crawford, E Bridie Clemens, Thi HO Nguyen, Katherine Kedzierska, Nicole L La Gruta, Philip Bradley, Paul G Thomas

Journal article  |  2017  |  Nature

Understanding CD8( ) T-cell responses toward the native and alternate HLA-A*02:01-restricted WT1 epitope

Thi HO Nguyen, Amabel CL Tan, Sue D Xiang, Anne Goubier, Kim L Harland, E Bridie Clemens, Magdalena Plebanski, Katherine Kedzierska

Journal article  |  2017  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

The role of CD27 in anti-viral T-cell immunity

Emma J Grant, Simone Nuessing, Sneha Sant, E Bridle Clemens, Katherine Kedzierska

Journal article  |  2017  |  CURRENT OPINION IN VIROLOGY

Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

EB Clemens, EJ Grant, Z Wang, S Gras, N Mifsud, P Illing, P Tipping, AW Purcell, J Rossjohn, A Miller, SYC Tong, K Kedzierska

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Human influenza viruses and CD8 T cell responses (vol 16, pg 132, 2016)

Emma J Grant, Sergio M Quinones-Parra, E Bridie Clemens, Katherine Kedzierska

Journal article  |  2016  |  CURRENT OPINION IN VIROLOGY

A Role of Influenza Virus Exposure History in Determining Pandemic Susceptibility and CD8( ) T Cell Responses

Sergio M Quinones-Parra, E Bridie Clemens, Zhongfang Wang, Hayley A Croom, Lukasz Kedzierski, Jodie McVernon, Dhanasekaran Vijaykrishna, Katherine Kedzierska

Journal article  |  2016  |  Journal of Virology

Corrigendum to 'Human influenza viruses and CD8 T cell responses' [Curr. Opin. Virol. 16 (2016) 132-142].

Emma J Grant, Sergio M Quiñones-Parra, E Bridie Clemens, Katherine Kedzierska

Journal article  |  2016  |  Current Opinion in Virology

Immune correlates of severe influenza disease in patients hospitalized with seasonal influenza viruses in Australia and with the novel avian H7N9 virus in China

O Nguyen, Z Wang, L Loh, EB Clemens, S Sant, M Koutsakos, A Hurt, K Laurie, T Kotsimbos, AC Cheng, D Jackson, LE Brown, N La Gruta, W Chen, J Xu, P Doherty, S Turner, K Kedzierska

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular basis for universal HLA-A(star)0201-restricted CD8( ) T-cell immunity against influenza viruses

Sophie A Valkenburg, Tracy M Josephs, E Bridie Clemens, Emma J Grant, Thi HO Nguyen, George C Wang, David A Price, Adrian Miller, Steven YC Tong, Paul G Thomas, Peter C Doherty, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

E Bridie Clemens, Emma J Grant, Zhongfang Wang, Stephanie Gras, Peta Tipping, Jamie Rossjohn, Adrian Miller, Steven YC Tong, Katherine Kedzierska

Journal article  |  2016  |  IMMUNOLOGY AND CELL BIOLOGY

Human influenza viruses and CD8( ) T cell responses

Emma J Grant, Sergio M Quinones-Parra, E Bridie Clemens, Katherine Kedzierska

Journal article  |  2016  |  CURRENT OPINION IN VIROLOGY

SOCS4 is dispensable for an efficient recall response to influenza despite being required for primary immunity

Lukasz Kedzierski, E Bridie Clemens, Nicola L Bird, Benjamin T Kile, Gabrielle T Belz, Nicos A Nicola, Katherine Kedzierska, Sandra E Nicholson

Journal article  |  2015  |  Immunology & Cell Biology

Fixed Expression of Single Influenza Virus-Specific TCR Chains Demonstrates the Capacity for TCR alpha- and beta-Chain Diversity in the Face of Peptide-MHC Class I Specificity

E Bridie Clemens, Peter C Doherty, Nicole L La Gruta, Stephen J Turner

Journal article  |  2015  |  The Journal of Immunology

Suppressor of Cytokine Signaling 4 (SOCS4) Protects against Severe Cytokine Storm and Enhances Viral Clearance during Influenza Infection

Lukasz Kedzierski, Edmond M Linossi, Tatiana B Kolesnik, E Bridie Day, Nicola L Bird, Benjamin T Kile, Gabrielle T Belz, Donald Metcalf, Nicos A Nicola, Katherine Kedzierska, Sandra E Nicholson

Journal article  |  2014  |  PLOS PATHOGENS

Epigenetic plasticity of Cd8a locus during CD8( ) T-cell development and effector differentiation and reprogramming

Kim L Harland, E Bridie Day, Simon H Apte, Brendan E Russ, Peter C Doherty, Stephen J Turner, Anne Kelso

Journal article  |  2014  |  NATURE COMMUNICATIONS

A semi-invariant V(alpha)10( ) T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties

Adam P Uldrich, Onisha Patel, Garth Cameron, Daniel G Pellicci, E Bridie Day, Lucy C Sullivan, Konstantinos Kyparissoudis, Lars Kjer-Nielsen, Julian P Vivian, Benjamin Cao, Andrew G Brooks, Spencer J Williams, Petr Illarionov, Gurdyal S Besra, Stephen J Turner, Steven A Porcelli, James McCluskey, Mark J Smyth, Jamie Rossjohn, Dale I Godfrey

Journal article  |  2011  |  Nature Immunology

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8( ) T-cell responses

E Bridie Day, Carole Guillonneau, Stephanie Gras, Nicole L La Gruta, Dario AA Vignali, Peter C Doherty, Anthony W Purcell, Jamie Rossjohn, Stephen J Turner

Journal article  |  2011  |  Proceedings of the National Academy of Sciences of the United States of America

Effect of MHC Class I Diversification on Influenza Epitope-Specific CD8( ) T Cell Precursor Frequency and Subsequent Effector Function

E Bridie Day, Kim L Charlton, Nicole L La Gruta, Peter C Doherty, Stephen J Turner

Journal article  |  2011  |  Journal of Immunology

Fixing an irrelevant TCR alpha chain reveals the importance of TCR beta diversity for optimal TCR alpha beta pairing and function of virus-specific CD8( ) T cells

Sophie A Valkenburg, E Bridie Day, Natasha G Swan, Hayley A Croom, Francis R Carbone, Peter C Doherty, Stephen J Turner, Katherine Kedzierska

Journal article  |  2010  |  European Journal of Immunology

The context of epitope presentation can influence functional quality of recalled influenza A virus-specific memory CD8( ) T cells

E Bridie Day, Weiguang Zeng, Peter C Doherty, David C Jackson, Katherine Kedzierska, Stephen J Turner

Journal article  |  2007  |  Journal of Immunology

Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage

Katherine Kedzierska, E Bridie Day, Jing Pi, Stephen B Heard, Peter C Doherty, Stephen J Turner, Stanley Perlman

Journal article  |  2006  |  Journal of Immunology