Andrew Cochrane

Associations Between Systemic and Cerebral Inflammation in an Ovine Model of Cardiopulmonary Bypass.

Khalid Elsaafien, Jasmine M Sloan, Roger G Evans, Andrew D Cochrane, Bruno Marino, Peter R McCall, Sally G Hood, Song T Yao, Willian S Korim, Simon R Bailey, Alemayehu H Jufar, Rachel M Peiris, Rinaldo Bellomo, Lachlan F Miles, Clive N May, Yugeesh R Lankadeva

Journal article  |  2023  |  Anesth Analg

BACKGROUND: Intraoperative inflammation may contribute to postoperative neurocognitive disorders after cardiac surgery requiring c..

Association Between Changes in Norepinephrine Infusion Rate and Urinary Oxygen Tension After Cardiac Surgery.

Johnny Vogiatjis, Khin M Noe, Andrea Don, Andrew D Cochrane, Michael ZL Zhu, Julian A Smith, Jennifer P Ngo, Andrew Martin, Amanda G Thrift, Rinaldo Bellomo, Roger G Evans

Journal article  |  2023  |  J Cardiothorac Vasc Anesth

OBJECTIVES: To determine if the administration of norepinephrine to patients recovering from on-pump cardiac surgery is associated..

Influence of moderate hypothermia on renal and cerebral haemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep

Alemayehu H Jufar, Clive N May, Roger G Evans, Andrew D Cochrane, Bruno Marino, Sally G Hood, Peter R McCall, Rinaldo Bellomo, Yugeesh R Lankadeva

Journal article  |  2022  |  ACTA PHYSIOLOGICA

AIM: Cardiac surgery requiring cardiopulmonary bypass (CPB) can result in renal and cerebral injury. Intraoperative tissue hypoxia..

Renal and Cerebral Hypoxia and Inflammation During Cardiopulmonary Bypass

Alemayehu H Jufar, Yugeesh R Lankadeva, Clive N May, Andrew D Cochrane, Bruno Marino, Rinaldo Bellomo, Roger G Evans

Journal article  |  2022  |  COMPREHENSIVE PHYSIOLOGY

Cardiac surgery-associated acute kidney injury and brain injury remain common despite ongoing efforts to improve both the equipmen..

Intra-operative and early post-operative prediction of cardiac surgery-associated acute kidney injury: Urinary oxygen tension compared with plasma and urinary biomarkers

Khin M Noe, Jennifer P Ngo, Andrew Martin, Michael ZL Zhu, Andrew D Cochrane, Julian A Smith, Amanda G Thrift, Harshil Singh, Roger G Evans

Journal article  |  2021  |  CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Acute kidney injury (AKI) is a common and serious post-operative complication of cardiac surgery. The value of a predictive biomar..

Intraoperative renal hypoxia and risk of cardiac surgery-associated acute kidney injury.

Jennifer P Ngo, Khin M Noe, Michael ZL Zhu, Andrew Martin, Meg Ollason, Andrew D Cochrane, Julian A Smith, Amanda G Thrift, Roger G Evans

Journal article  |  2021  |  J Card Surg

BACKGROUND: Acute kidney injury (AKI) is common after cardiac surgery requiring cardiopulmonary bypass. Renal hypoxia may precede ..

Machine Learning Algorithms for Predicting and Risk Profiling of Cardiac Surgery-Associated Acute Kidney Injury.

Jahan C Penny-Dimri, Christoph Bergmeir, Christopher M Reid, Jenni Williams-Spence, Andrew D Cochrane, Julian A Smith

Journal article  |  2021  |  Semin Thorac Cardiovasc Surg

Using a large national database of cardiac surgical procedures, we applied machine learning (ML) to risk stratification and profil..

Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man

Roger G Evans, Andrew D Cochrane, Sally G Hood, Naoya Iguchi, Bruno Marino, Rinaldo Bellomo, Peter R McCall, Nobuki Okazaki, Julian A Smith, Michael ZL Zhu, Jennifer P Ngo, Khin M Noe, Andrew Martin, Amanda G Thrift, Yugeesh R Lankadeva, Clive N May

Journal article  |  2021  |  PERFUSION-UK

INTRODUCTION: The renal medulla is susceptible to hypoxia during cardiopulmonary bypass (CPB), which may contribute to the develop..

What is the role of surgical lung biopsy in interstitial lung disease?

Andrew Cochrane, Xun Li

Journal article  |  2021  |  ANZ J Surg

M04 Predictors and Outcomes of Pleurodesis in Malignant Pleural Effusion

J Brookes, A Cochrane, J Smith

Journal article  |  2021  |  Heart, Lung and Circulation