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Email

kevin.sek@unimelb.edu.au

Credentials


Position
Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology
ORCID

0000-0003-4634-7600

Dr Kevin Sek

Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology

12 Scholarly works
0 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8 T cells in lymph nodes
    DOI: 10.1038/s41590-026-02419-4
  • 2025

    Journal article

    Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
    DOI: 10.1038/s41467-025-59021-9
  • 2025

    Journal article

    Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
    DOI: 10.1038/s41586-025-09212-7
  • 2024

    Journal article

    FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
    DOI: 10.1038/s41586-024-07242-1
  • 2023

    Journal article

    A2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses
    DOI: 10.1038/s41467-023-42734-0
  • 2023

    Journal article

    TSTEM-like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models
    DOI: 10.1126/scitranslmed.abk1900
  • 2022

    Journal article

    PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity
    DOI: 10.1158/2159-8290.CD-21-0694
Kevin Sek

RECENT SCHOLARLY WORKS

  • 2021

    Journal article

    Adoptive transfer of tumor-specific Th9 cells eradicates heterogeneous antigen-expressing tumor cells
    DOI: 10.1016/j.ccell.2021.10.013
  • 2021

    Journal article

    CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy
    DOI: 10.1038/s41467-021-23331-5
  • 2020

    Journal article

    IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors
    DOI: 10.1016/j.ymthe.2020.07.018

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