Dr Kevin Sek
Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology
24 Scholarly works
0 Projects
HIGHLIGHTS
2026
Journal article
ENHANCING CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY FOR PAEDIATRIC SARCOMA THROUGH CAR T ENGINEERING AND TUMOUR MICROENVIRONMENT REWIRING
DOI: 10.1016/j.jcyt.2026.1022252026
Journal article
Cytokine armored CAR T cells for cancer immunotherapy
DOI: 10.1111/imcb.701122026
Journal article
Abstract 144: In vivo CAR mRNA engineering of both adaptive and myeloid cells enables potent anti-tumor control of solid cancers.
DOI: 10.1158/1538-7445.am2026-1442026
Journal article
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8 T cells in lymph nodes
DOI: 10.1038/s41590-026-02419-42025
Journal article
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
DOI: 10.1038/s41467-025-59021-92025
Journal article
Targeting PTPN2 enhances human CAR T cell efficacy and the development of long-term memory in mouse xenograft models
DOI: 10.1126/scitranslmed.adk06272025
Journal article
Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
DOI: 10.1038/s41586-025-09212-7
RECENT SCHOLARLY WORKS
2024
Journal article
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
DOI: 10.1038/s41586-024-07242-12023
Journal article
A2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses
DOI: 10.1038/s41467-023-42734-02023
Journal article
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity
DOI: 10.1016/j.celrep.2023.113014