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Email

isabelle.munoz@unimelb.edu.au

Credentials


Position
Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology

Dr Isabelle Munoz

Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology

13 Scholarly works
1 Projects

HIGHLIGHTS

  • 2026

    Journal article

    High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion
    DOI: 10.1038/s41467-026-69671-y
  • 2026

    Journal article

    Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8 T cells in lymph nodes
    DOI: 10.1038/s41590-026-02419-4
  • 2026

    Journal article

    CDK4/6 inhibition enhances CAR-T cell therapy in solid tumors
    DOI: 10.1016/j.ymthe.2026.03.024
  • 2025

    Journal article

    Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
    DOI: 10.1038/s41467-025-59021-9
  • 2025

    Journal article

    Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
    DOI: 10.1038/s41586-025-09212-7
  • 2024

    Journal article

    Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells
    DOI: 10.3389/fphar.2024.1396710
  • 2024

    Research grants (other domestic)

    Generation of CAR T Cells With Improved Metabolic Fitness and Persistence
Isabelle Munoz

RECENT SCHOLARLY WORKS

  • 2024

    Journal article

    FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
    DOI: 10.1038/s41586-024-07242-1
  • 2023

    Conference Proceedings

    Regulation of exhausted CD8 T cell differentiation by IKZF transcription factors
    DOI: 10.1158/2326-6074.TUMIMM23-PR01
  • 2023

    Journal article

    A2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses
    DOI: 10.1038/s41467-023-42734-0
  • 2022

    Journal article

    PARP11 interfer(on)es with CAR T cell efficacy
    DOI: 10.1038/s43018-022-00406-w

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