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Email

sjwill@unimelb.edu.au

Credentials


Position
Professor
School of Chemistry
Education
PhD
The University of Western Australia
Bachelors Degree (Honours)
The University of Western Australia
ORCID

0000-0001-6341-4364

Prof Spencer Williams

Professor
School of Chemistry

310 Scholarly works
62 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Cosmopolitan marine bacteria facilitate a vast phytoplankton-derived sulfonate-based carbon flow through sulfoquinovosidases
    DOI: 10.1038/s41467-025-66898-z
  • 2026

    Journal article

    Total Syntheses of Roseochelins A and B Using an Oxidative Decarboxylation Strategy
    DOI: 10.1021/acs.orglett.6c00757
  • 2026

    Journal article

    The return of metabolism: biochemistry and physiology of glycolysis
    DOI: 10.1111/brv.70104
  • 2026

    Journal article

    Catalyzing Carbohydrate Cleavage: Glycosidases and Their Mechanisms
    DOI: 10.1021/acs.chemrev.5c00803
  • 2025

    Research grants (other domestic)

    Near Single Molecule Sensitivity Mass Spectrometry for Multi-Omic Research
  • 2020

    Research grants (ARC, NHMRC, MRFF)

    Targeting Carbohydrate Metabolism in Leishmania
  • 2018

    Research Grant

    Characterisation and Development of Type-2 NKT Cells
Spencer Williams

Latest Honours,
Awards and Fellowships


2021
HG Smith Memorial Award Royal Australian Chemical Institute
2014
David Syme Research Prize (2014) University of Melbourne
2014
Australian Research Council Future Fellow
2011
Grimwade Prize for Industrial Chemistry University of Melbourne

RECENT SCHOLARLY WORKS

  • 2026

    Journal article

    A short synthesis of p-nitrophenyl α-D-xylofuranoside and β-D-arabinofuranoside employing a Mitsunobu glycosylation
    DOI: 10.1016/j.carres.2025.109802
  • 2026

    Journal article

    Structural and mechanistic basis of sulfolytic C–S bond cleavage by an Fe(ii)/α-ketoglutarate-dependent sulfoquinovose dioxygenase
    DOI: 10.1039/d5sc09188h
  • 2026

    Journal article

    Metal-Dependent 2-Keto-3,6-dideoxy-6-sulfo-gluconate (KDSG) Aldolase: Decoding the Key C─C Bond Cleaving Step in Bacterial Sulfoglycolysis
    DOI: 10.1002/chem.70857
  • 2025

    Journal article

    Bridging a Gap in Marine Sulfur Cycling: Discovery of a d-Cysteinolic Acid Degradation Pathway
    DOI: 10.1021/jacs.5c11066
  • 2025

    Journal article

    Chemical Probe Approach Reveals Endo-α-mannosidase Triages Misfolded Glycoproteins in the Calnexin/Calreticulin Cycle
    DOI: 10.1021/acschembio.5c00532
  • 2025

    Journal article

    Tandem sulfofucolytic-sulfolactate sulfolyase pathway for catabolism of the rare sulfosugar sulfofucose
    DOI: 10.1128/mbio.01840-25

RECENT PROJECTS

  • 2023

    Research grants (international)

    Understanding the Role of D-Arabinan Degrading Enzymes in Mycobacterial Physiology and Disease
  • 2024

    Research grants (ARC, NHMRC, MRFF)

    Unlocking the Secret Chemistry of Organosulfur Biodegradation

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