A/Prof Michael Griffin
Principal Research Fellow
Department of Biochemistry and Pharmacology
136 Scholarly works
29 Projects
HIGHLIGHTS
2025
Journal article
Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae.
DOI: 10.64898/2025.12.10.6934822025
Journal article
The Structure of the Apolipoprotein A-I Monomer Provides Insights Into Its Oligomerisation and Lipid-binding Mechanisms
DOI: 10.1016/j.jmb.2025.1693942021
Research Grant
New Biomolecular Capabilities for the Melbourne Magnetic Resonance Facility
2021
Research grants (ARC, NHMRC, MRFF)
ARC Training Centre for Cryo-Electron Microscopy of Membrane Proteins for Drug Discovery (CCeMMP)
2019
Journal article
The structure of the PA28–20S proteasome complex from Plasmodium falciparum and implications for proteostasis
DOI: 10.1038/s41564-019-0524-42017
Research Grant
Molecular Structure Elucidation Facility
2015
Journal article
Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation
DOI: 10.1038/nsmb.3127
RECENT SCHOLARLY WORKS
2025
Journal article
Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target
DOI: 10.1371/journal.ppat.10130572025
Journal article
The structure of the IL-11 signalling complex provides insight into receptor variants associated with craniosynostosis
DOI: 10.1111/febs.173072024
Journal article
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
DOI: 10.1038/s41467-024-45224-z2024
Journal article
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
DOI: 10.1371/journal.ppat.10124292024
Journal article
Heterochromatin protein 1 alpha (HP1α) undergoes a monomer to dimer transition that opens and compacts live cell genome architecture
DOI: 10.1093/nar/gkae7202024
Journal article
Craniosynostosis-associated variants in the IL-11R complex: new insights and questions
DOI: 10.1111/febs.170782024
Journal article
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
DOI: 10.7554/elife.92307.32024
Journal article
Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter
DOI: 10.7554/eLife.92307