A/Prof Michael Griffin
Principal Research Fellow
Department of Biochemistry and Pharmacology
149 Scholarly works
29 Projects
HIGHLIGHTS
2026
Journal article
Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae.
DOI: 10.1093/nar/gkag9532026
Journal article
Deep learning-based quantification of collagen and associated features from H&E-stained whole slide pathology images across cancer types
DOI: 10.1038/s43856-026-01809-x2021
Research Grant
New Biomolecular Capabilities for the Melbourne Magnetic Resonance Facility
2021
Research grants (ARC, NHMRC, MRFF)
ARC Training Centre for Cryo-Electron Microscopy of Membrane Proteins for Drug Discovery (CCeMMP)
2019
Journal article
The structure of the PA28–20S proteasome complex from Plasmodium falciparum and implications for proteostasis
DOI: 10.1038/s41564-019-0524-42017
Research Grant
Molecular Structure Elucidation Facility
2015
Journal article
Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation
DOI: 10.1038/nsmb.3127
RECENT SCHOLARLY WORKS
2025
Journal article
Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae.
DOI: 10.64898/2025.12.10.6934822025
Journal article
Digital Versus Manual PD-L1 Scoring in Advanced NSCLC From the IMpower110 and IMpower150 Trials.
DOI: 10.1016/j.jtho.2025.07.1312025
Journal article
The Structure of the Apolipoprotein A-I Monomer Provides Insights Into Its Oligomerisation and Lipid-binding Mechanisms
DOI: 10.1016/j.jmb.2025.1693942025
Journal article
Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target
DOI: 10.1371/journal.ppat.10130572025
Journal article
The structure of the IL-11 signalling complex provides insight into receptor variants associated with craniosynostosis
DOI: 10.1111/febs.173072024
Journal article
A feasibility study using quantitative and interpretable histological analyses of celiac disease for automated cell type and tissue area classification.
DOI: 10.1038/s41598-024-79570-12024
Journal article
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
DOI: 10.1371/journal.ppat.10124292024
Journal article
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
DOI: 10.1038/s41467-024-45224-z