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Contact


Email

petermc@unimelb.edu.au

Credentials


Position
Honorary (Professorial Fellow)
Department of Medical Biology (WEHI)
Education
Bachelors Degree
Adelaide University
PhD
Adelaide University
ORCID

0000-0001-8537-4041

Prof Peter Colman

Honorary (Professorial Fellow)
Department of Medical Biology (WEHI)

213 Scholarly works
1 Projects

HIGHLIGHTS

  • 2025

    Journal article

    Computational design of potent and selective binders of BAK and BAX
    DOI: 10.1126/sciadv.adt4170
  • 2024

    Journal article

    Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids
    DOI: 10.1111/febs.17031
  • 2023

    Journal article

    The crystal structure of detergent-activated BAK dimers provides insights into BAK activation steps and how they stabilise membrane pores
    DOI: 10.1107/s205327332308912x
  • 2022

    Journal article

    Ion currents through Kir potassium channels are gated by anionic lipids
    DOI: 10.1038/s41467-022-28148-4
  • 2022

    Journal article

    An increase in mitochondrial TOM activates apoptosis to drive retinal neurodegeneration
    DOI: 10.1038/s41598-022-23280-z
  • 2022

    Journal article

    Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation
    DOI: 10.1038/s41418-022-00961-w
  • 2019

    Journal article

    Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
    DOI: 10.1038/s41467-019-10363-1
Peter Colman

Latest Honours,
Awards and Fellowships


1989
Fellow of the Australian Academy of Science (FAA)

RECENT SCHOLARLY WORKS

  • 2022

    Journal article

    The Bak core dimer focuses triacylglycerides in the membrane
    DOI: 10.1016/j.bpj.2021.12.043
  • 2021

    Journal article

    Structure of detergent-activated BAK dimers derived from the inert monomer
    DOI: 10.1016/j.molcel.2021.03.014
  • 2021

    Journal article

    Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2
    DOI: 10.1021/acsinfecdis.0c00700
  • 2021

    Journal article

    Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XLand BCL-2
    DOI: 10.1021/acs.jmedchem.0c01771

RECENT PROJECTS

  • 2010

    Research Grant

    Novel Compounds to Disrupt Protein-Protein Interactions

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