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Contact


Email

jamesm1@unimelb.edu.au

Credentials


Position
Assistant Vice-Chancellor (Research)
Office of the DVC Research
Education
Doctoral Degree (Research) / PhD
The University of Western Australia
Bachelors Degree
The University of Western Australia
Bachelors Degree
The University of Western Australia
ORCID

0000-0002-8597-815X

Prof McCluskey James

Assistant Vice-Chancellor (Research)
Office of the DVC Research

567 Scholarly works
28 Projects

HIGHLIGHTS

  • 2024

    Journal article

    MAIT cell-MR1 reactivity is highly conserved across multiple divergent species
    DOI: 10.1016/j.jbc.2024.107338
  • 2022

    Research grants (ARC, NHMRC, MRFF)

    Immunity Mediated by MHC Class I-Related Protein (MR1)
  • 2020

    Research grants (international)

    Investigating the Basis of MAIT Cell Antigen Potency (NIH R01 Resubmission)
  • 2019

    Journal article

    Characterization of Human Mucosal-associated Invariant T (MAIT) Cells
    DOI: 10.1002/cpim.90
  • 2017

    Journal article

    Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells
    DOI: 10.1038/ni.3679
  • 2017

    Research Grant

    Antigen Presentation, Recognition and the Immune Response
  • 2014

    Journal article

    T-cell activation by transitory neo-antigens derived from distinct microbial pathways
    DOI: 10.1038/nature13160
McCluskey James

Latest Honours,
Awards and Fellowships


2022
University of Melbourne
2016
Victoria Prize for Life Sciences (joint with Prof Jamie Rossjohn) State Government of Victoria
2015
GSK Award for Research Excellence (ARE) GSK
2015
University of Melbourne

RECENT SCHOLARLY WORKS

  • 2026

    Journal article

    A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells.
    DOI: 10.1002/chem.71494
  • 2026

    Journal article

    Allelic variation alters expression and antigen presentation of MR1 allomorphs
    DOI: 10.1016/j.jbc.2026.111470
  • 2026

    Journal article

    Adenoviral Inciting Antigen and Somatic Hypermutation in VITT
    DOI: 10.1056/NEJMoa2514824
  • 2026

    Journal article

    Adenoviral Core Protein VII-Driven Cross-Reactivity of Anti-PF4 Antibodies as a Trigger for VITT Pathogenesis
    DOI: 10.1055/s-0045-1815618
  • 2025

    Journal article

    A molecular basis underpinning TRBV28 T-cell receptor recognition of MR1–antigen
    DOI: 10.1016/j.jbc.2025.110416
  • 2025

    Journal article

    Molecular Insights Into MR1-Mediated T Cell Immunity: Lessons Learned and Unanswered Questions
    DOI: 10.1111/imr.70033
  • 2025

    Journal article

    Cigarette smoke components modulate the MR1–MAIT axis
    DOI: 10.1084/jem.20240896
  • 2025

    Journal article

    Brain-Resident MAIT Cells Infiltrate GL261 Tumors, and Activated MAIT Cell Signatures Are Associated With Improved Outcomes in Glioma
    DOI: 10.1212/NXI.0000000000200546

Acknowledgement of Country

We acknowledge Aboriginal and Torres Strait Islander people as the Traditional Owners of the unceded lands on which we work, learn and live. We pay respect to Elders past, present and future, and acknowledge the importance of Indigenous knowledge in the Academy.

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Victoria, 3010, Australia

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