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Contact


Email

jamesm1@unimelb.edu.au

Credentials


Position
Assistant Vice-Chancellor (Research)
Office of the DVC Research
Education
Doctorate (Research)
The University of Western Australia
Bachelors Degree
The University of Western Australia
Bachelors Degree
The University of Western Australia
ORCID

0000-0002-8597-815X

Prof McCluskey James

Assistant Vice-Chancellor (Research)
Office of the DVC Research

565 Scholarly works
21 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Allelic variation alters expression and antigen presentation of MR1 allomorphs
    DOI: 10.1016/j.jbc.2026.111470
  • 2026

    Journal article

    Adenoviral Inciting Antigen and Somatic Hypermutation in VITT
    DOI: 10.1056/NEJMoa2514824
  • 2026

    Journal article

    Adenoviral Core Protein VII-Driven Cross-Reactivity of Anti-PF4 Antibodies as a Trigger for VITT Pathogenesis
    DOI: 10.1055/s-0045-1815618
  • 2025

    Journal article

    A molecular basis underpinning TRBV28 T-cell receptor recognition of MR1–antigen
    DOI: 10.1016/j.jbc.2025.110416
  • 2022

    Research grants (ARC, NHMRC, MRFF)

    Immunity Mediated by MHC Class I-Related Protein (MR1)
  • 2020

    Research grants (international)

    Investigating the Basis of MAIT Cell Antigen Potency (NIH R01 Resubmission)
  • 2017

    Research Grant

    Antigen Presentation, Recognition and the Immune Response
McCluskey James

Latest Honours,
Awards and Fellowships


2022
University of Melbourne
2016
Victoria Prize for Life Sciences (joint with Prof Jamie Rossjohn) State Government of Victoria
2015
GSK Award for Research Excellence (ARE) GSK
2015
University of Melbourne

RECENT SCHOLARLY WORKS

  • 2025

    Journal article

    Molecular Insights Into MR1-Mediated T Cell Immunity: Lessons Learned and Unanswered Questions
    DOI: 10.1111/imr.70033
  • 2025

    Journal article

    Cigarette smoke components modulate the MR1–MAIT axis
    DOI: 10.1084/jem.20240896
  • 2025

    Journal article

    Brain-Resident MAIT Cells Infiltrate GL261 Tumors, and Activated MAIT Cell Signatures Are Associated With Improved Outcomes in Glioma
    DOI: 10.1212/NXI.0000000000200546
  • 2024

    Journal article

    MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells
    DOI: 10.1073/pnas.2414792121
  • 2024

    Journal article

    MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection
    DOI: 10.1126/sciimmunol.adp9841
  • 2024

    Journal article

    Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis
    DOI: 10.1002/ange.202400632

RECENT PROJECTS

  • 2024

    Research grants (ARC, NHMRC, MRFF)

    The Molecular Basis of T Cell Receptor Cross-Reactivity Between MHC and MR1
  • 2020

    Research Grant

    Defining Immune Responses in COVID-19 to Understand Susceptibility and Target Treatments

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