Ms Karena Last
Research Assistant
Department of Biochemistry and Pharmacology
39 Scholarly works
0 Projects
HIGHLIGHTS
2026
Journal article
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
DOI: 10.1016/j.cell.2025.10.0282025
Journal article
Complex II assembly drives metabolic adaptation to OXPHOS dysfunction
DOI: 10.1126/sciadv.adr60122019
Journal article
ADAMTS-9 in mouse cartilage has aggrecanase activity that is distinct from ADAMTS-4 and ADAMTS-5
DOI: 10.3390/ijms200305732018
Journal article
An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2
DOI: 10.1172/jci.insight.957042016
Journal article
A disintegrin and metalloproteinase with thrombospondin motifs-5 (ADAMTS-5) forms catalytically active oligomers
DOI: 10.1074/jbc.M115.7048172015
Journal article
Bioactivity in an aggrecan 32-mer fragment is mediated via toll-like receptor 2
DOI: 10.1002/art.390632014
Conference Proceedings
BIOACTIVITY IN AN AGGRECAN 32MER FRAGMENT IS MEDIATED VIA TOLL-LIKE RECEPTORS
DOI: 10.1016/j.joca.2014.02.043
RECENT SCHOLARLY WORKS
2012
Journal article
Aggrecanase cleavage in juvenile idiopathic arthritis patients is minimally detected in the aggrecan interglobular domain but robust at the aggrecan C-terminus
DOI: 10.1002/art.346652012
Journal article
Evidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo
DOI: 10.1242/bio.20125472012
Conference Proceedings
AGGRECAN FRAGMENTS IN THE SYNOVIAL FLUID OF OSTEOARTHRITIS AND JUVENILE IDIOPATHIC ARTHRITIS PATIENTS REVEALS DIFFERENCES IN THE SPECIFICITY OF AGGRECANASE CLEAVAGE IN THE INTERGLOBULAR DOMAIN, BUT NOT IN THE CHONDROITIN-SULPHATE-RICH REGION
DOI: 10.1016/j.joca.2012.02.142