Dr. Roy Kong
Research Fellow
Medicine - St Vincent's Hospital
11 Scholarly works
7 Projects
HIGHLIGHTS
2020
Conference Proceedings
Oral delivery of the anti-fibrotic, FT011, achieves safe and robust intraocular levels of exposure in subjects undergoing glaucoma filtration surgery
2020
Conference Proceedings
OCX063, a novel small molecule drug, is protective against inflammatory, fibrotic and angiogenic phenotypes in retinal cultures
2019
Research Contracts
2019-CT-PC-06
2019
Conference Proceedings
Oral administration of the novel small molecule drug OCX063 protects against inflammation and vascular pathology in a rat diabetic retinopathy (DR) model
2017
Conference Proceedings
OCX063, A Novel Small Molecule Drug, Exhibits Anti-Inflammatory and Anti-Fibrotic Properties in Retinal Cultures
2017
Conference Proceedings
The protective effect of OCX063 on reducing neovascularization and lesion size in a mouse model of choroidal neovascularization.
2014
Journal article
Mapping Key Regions of the RXFP2 Low-Density Lipoprotein Class-A Module That Are Involved in Signal Activation
DOI: 10.1021/bi500797d
RECENT SCHOLARLY WORKS
2013
Journal article
The Relaxin Receptor (RXFP1) Utilizes Hydrophobic Moieties on a Signaling Surface of Its N-terminal Low Density Lipoprotein Class A Module to Mediate Receptor Activation
DOI: 10.1074/jbc.M113.4996402013
Journal article
Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules.
DOI: 10.3389/fendo.2013.001712010
Journal article
Membrane receptors: Structure and function of the relaxin family peptide receptors
DOI: 10.1016/j.mce.2010.02.0032009
Conference Proceedings
Resolving the Unconventional Mechanisms Underlying RXFP1 and RXFP2 Receptor Function
DOI: 10.1111/j.1749-6632.2009.03949.x
RECENT PROJECTS
2021
Research Contracts
The effects of exosome preparations on fibrosis in TGF-β stimulated, cultured rat renal mesangial cells
2021
Research Contracts
CTPC13
2021
Research Contracts
Contribution of a novel receptor protein to inflammatory and fibrotic responses in immune cells
2020
Research Contracts
Comparison of the in vitro efficacy of OCX063 with Tranilast in RPE cells