Dr James Holden
Senior Research Fellow - Immunology, CRC
Melbourne Dental School
42 Scholarly works
5 Projects
HIGHLIGHTS
2025
Journal article
The Effect of Bioceramic-Based Root Canal Sealers on the Cell Viability and Cytotoxicity of Human Periodontal Ligament Fibroblast cell line (An in vitro study)
DOI: 10.33899/rdenj.2024.152429.12722025
Journal article
Multi-disciplinary approaches paving the way for clinically effective peptide vaccines for cancer
DOI: 10.1038/s41541-025-01118-92025
Thesis / Dissertation
Novel calcium phosphate nanoparticles as vaccine adjuvants and delivery agents
2025
Research grants (ARC, NHMRC, MRFF)
Preclinical Development of a Multidomain Vaccine for Periodontitisassociated Alzheimer's Disease (PAD Vax)
2024
Journal article
Chronic Oral Inoculation of Porphyromonas gingivalis and Treponema denticola Induce Different Brain Pathologies in a Mouse Model of Alzheimer Disease
DOI: 10.1093/infdis/jiae2862020
Research grants (ARC, NHMRC, MRFF)
Reversing Antibiotic Resistance in Superbugs
2020
Research Grant
Reversing Antibiotic Resistance in Superbugs
RECENT SCHOLARLY WORKS
2024
Journal article
Biocompatibility and hard tissue-forming ability of CPP-ACP- and CPP- ACFP-modified calcium silicate-based cements
DOI: 10.33899/rdenj.2024.151060.12642024
Journal article
Biocompatibility and hard tissue-forming ability of CPP-ACP- and CPP- ACFP-modified calcium silicate-based cements
DOI: 10.33899/rdenj.2024.151060.012642024
Journal article
Dimerization and lysine substitution of melittin have differing effects on bacteria
DOI: 10.3389/fphar.2024.14434972022
Journal article
Star-Peptide Polymers are Multi-Drug-Resistant Gram-Positive Bacteria Killers
DOI: 10.1021/acsami.1c237342022
Journal article
Enhancing proline-rich antimicrobial peptide action by homodimerization: Influence of bifunctional linker
DOI: 10.1039/d1sc05662j2022
Journal article
The Potential of Modified and Multimeric Antimicrobial Peptide Materials as Superbug Killers
DOI: 10.3389/fchem.2021.7954332021
Journal article
The Potential of Calcium Phosphate Nanoparticles as Adjuvants and Vaccine Delivery Vehicles
DOI: 10.3389/fmats.2021.788373
RECENT PROJECTS
2018
Research Grant
Antimicrobial Peptides That Target Periodontal Pathogens