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Email

prg@unimelb.edu.au

Credentials


Position
Professor and Reader
Department of Biochemistry and Pharmacology
Education
PhD
University of New South Wales
Bachelors Degree
University of New South Wales
ORCID

0000-0002-0323-449X

Prof Paul Gooley

Professor and Reader
Department of Biochemistry and Pharmacology

210 Scholarly works
54 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK biobank
    DOI: 10.1016/j.isci.2025.114316
  • 2025

    Journal article

    New directions in the multifunctionality of RNA viruses: insights from the rabies virus P-protein
    DOI: 10.1016/j.coviro.2025.101496
  • 2025

    Journal article

    The Allosteric Mechanism of G-Protein-Coupled Receptors is Induced Fit, Not Conformational Selection
    DOI: 10.1002/bies.70082
  • 2025

    Journal article

    The Structure of the Apolipoprotein A-I Monomer Provides Insights Into Its Oligomerisation and Lipid-binding Mechanisms
    DOI: 10.1016/j.jmb.2025.169394
  • 2021

    Research Grant

    Hydrogen-Deuterium Exchange System - a Missing Link in Protein Analysis
  • 2021

    Research Grant

    New Biomolecular Capabilities for the Melbourne Magnetic Resonance Facility
  • 2021

    Research grants (ARC, NHMRC, MRFF)

    Relaxin Receptor Structural Determination to Aid Therapeutic Development
Paul Gooley

Latest Honours,
Awards and Fellowships


2021
University of Melbourne

RECENT SCHOLARLY WORKS

  • 2025

    Journal article

    The Replication Function of Rabies Virus P Protein Is Regulated by a Novel Phosphorylation Site in the N-Terminal N Protein-Binding Region
    DOI: 10.3390/v17081075
  • 2025

    Journal article

    Analysis of mechanisms of the rabies virus P protein-nucleocapsid interaction using engineered N-protein peptides and potential applications in antivirals design
    DOI: 10.1016/j.antiviral.2024.106075
  • 2025

    Journal article

    Machine learning and multi-omics in precision medicine for ME/CFS
    DOI: 10.1186/s12967-024-05915-z
  • 2025

    Journal article

    Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein
    DOI: 10.1126/scisignal.ads2210
  • 2025

    Journal article

    Conformational dynamics, RNA binding, and phase separation regulate the multifunctionality of rabies virus P protein
    DOI: 10.1038/s41467-025-65223-y
  • 2025

    Journal article

    Mapping cerebral blood flow in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and orthostatic intolerance: insights from a systematic review
    DOI: 10.1186/s12967-025-06954-w

RECENT PROJECTS

  • 2021

    Research contracts (non-grants)

    Identifying Disease Development Pathways and Exacerbating Factors in ME/CFS
  • 2025

    Research grants (ARC, NHMRC, MRFF)

    The Mechanism of Relaxin, a Novel Glucocorticoid Receptor Modulator

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