Prof Leann Tilley
Professor Emerita / Emeritus
Department of Biochemistry and Pharmacology
286 Scholarly works
40 Projects
HIGHLIGHTS
2019
Journal article
The structure of the PA28–20S proteasome complex from Plasmodium falciparum and implications for proteostasis
DOI: 10.1038/s41564-019-0524-42019
Research Grant
Nucleoside Sulphamates as Novel Antimalarials for the Treatment of Plasmodium Falciparum
2017
Journal article
Erythrocyte β spectrin can be genetically targeted to protect mice from malaria
DOI: 10.1182/bloodadvances.20170092742017
Research Grant
H2017-101 – HTL for Selective Plasmodium Proteasome Inhibitors as New Potent Resistance-Reversing Antimalarials.
2017
Research Grant
A Collaborative Electron Microscopy Pipeline for Structural Biology (Non-Arc Cash)
2012
Journal article
Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum
DOI: 10.1016/j.jsb.2011.09.0032012
Journal article
Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum
DOI: 10.1016/j.jsb.2011.09.003
RECENT SCHOLARLY WORKS
2026
Journal article
Potent reaction hijacking inhibitors of Plasmodium falciparum asparagine tRNA synthetase.
DOI: 10.64898/2026.05.15.7253882026
Journal article
Reaction hijacking of enzymes to generate potent therapeutic modulators in situ
DOI: 10.1016/j.tibs.2026.03.0032025
Journal article
Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target
DOI: 10.1371/journal.ppat.10130572025
Conference Proceedings
Understanding the drug resistance in the malaria parasite Plasmodium falciparum through high resolution imaging
DOI: 10.14293/apmc13-2025-00852025
Book Chapter
pH Regulation
DOI: 10.1007/978-1-4614-8326-7_322024
Journal article
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
DOI: 10.1038/s41467-024-45224-z2024
Journal article
A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
DOI: 10.1371/journal.ppat.10124292024
Journal article
Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus
DOI: 10.1038/s41467-024-50167-6