Dr Amanda Edgley
Academic Director, MDHS Honours Program
Faculty of Medicine, Dentistry and Health Sciences
85 Scholarly works
24 Projects
HIGHLIGHTS
2026
Journal article
Reduced PI3K(p110α) Activity in Cardiomyocytes Leads to Atrial Fibrosis and Increased Collagen Expression
DOI: 10.1016/j.hlc.2026.07.9012026
Journal article
Understanding The Dose Response Effects of PI3K on Atrial Fibrosis and Factors Released from The Heart
DOI: 10.1016/j.jmccpl.2025.1006232026
Journal article
Tissue response formation and maturation after cochlear implantation
DOI: 10.1016/j.heares.2025.1094752026
Journal article
Understanding the distinct role of PI3K(p110α) in cancer and the heart to prevent chemotherapy-induced cardiotoxicity: mechanisms and therapeutic opportunities
DOI: 10.3389/fcvm.2026.18911482022
Research Contracts
OCX Project - PC-24
2020
Research Grant
In Vivo Evaluation of a Novel Ketone Sensor
2018
Research Contracts
Testing Efficacy of Low Dose OCX063, OCX071 and FT011 on Albuminuria in Ren2 Rat Model of Diabetes [2018-Ocx-Pc-10]
RECENT SCHOLARLY WORKS
2025
Conference Proceedings
PI3K(p110a) regulates atrial function independent of fibrosis and is a critical regulator of atrial enlargement in a setting of pressure overload-Implications for atrial myopathy & atrial fibrillation
DOI: 10.1093/eurheartj/ehaf784.47482025
Journal article
An optimized plasmalogen modulating dietary supplement provides greater protection in a male than female mouse model of dilated cardiomyopathy
DOI: 10.1016/j.jmccpl.2024.1002732022
Journal article
Identification of Noninvasive Surrogates as Predictors of Response to FT011 in Kidney Disease
DOI: 10.1681/asn.20223311s1164b2022
Journal article
Inhibitory Effects of 3′,4′-Dihydroxyflavonol in a Mouse Model of Glaucoma Filtration Surgery and TGFβ1-Induced Responses in Human Tenon’s Fibroblasts
DOI: 10.1167/tvst.11.8.182022
Journal article
Aryl Hydrocarbon Receptor Inhibition Restores Indoxyl Sulfate-Mediated Endothelial Dysfunction in Rat Aortic Rings
DOI: 10.3390/toxins140201002022
Journal article
NP202 treatment improves left ventricular systolic function and attenuates pathological remodelling following chronic myocardial infarction
DOI: 10.1016/j.lfs.2021.120220
RECENT PROJECTS
2024
Research Contracts
Certa Therapeutics 2024-Ct-Pc-23
2022
Research Contracts
Effect of Novel Agents in the STNx Model of Chronic Kidney Disease