Prof Jerry Adams
Honorary (Professor Emeritus)
Department of Medical Biology (WEHI)
258 Scholarly works
0 Projects
HIGHLIGHTS
2024
Journal article
Mis-expression of GATA6 re-programs cell fate during early hematopoiesis
DOI: 10.1016/j.celrep.2024.1141592023
Journal article
Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia
DOI: 10.1182/blood.20220160902022
Journal article
Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL
DOI: 10.1182/blood.20210127752021
Journal article
BAX mitochondrial integration is regulated allosterically by its α1−α2 loop
DOI: 10.1038/s41418-021-00815-x2020
Journal article
Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
DOI: 10.1038/s41419-020-2463-72020
Journal article
Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma
DOI: 10.1038/s41388-019-1122-x2019
Journal article
BAX and BAK become killers without a BH3 trigger
DOI: 10.1038/s41422-019-0253-5
RECENT SCHOLARLY WORKS
2019
Journal article
By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737
DOI: 10.1038/s41418-018-0244-y2019
Journal article
BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
DOI: 10.1016/j.celrep.2019.03.0402019
Conference Proceedings
Targeting Mcl-1 is a promising strategy to kill mantle cell lymphoma cells