Prof David Huang
Honorary (Professorial Fellow)
Department of Medical Biology (WEHI)
235 Scholarly works
0 Projects
HIGHLIGHTS
2023
Journal article
Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia
DOI: 10.1182/blood.20220160902022
Journal article
Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy
DOI: 10.1182/blood.20220160402022
Journal article
Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL
DOI: 10.1182/blood.20210127752021
Journal article
Outcomes of patients with CLL sequentially resistant to both BCL2 and BTK inhibition
DOI: 10.1182/bloodadvances.20210050832021
Journal article
BCL2 and MCL1 inhibitors for hematologic malignancies
DOI: 10.1182/blood.20200067852021
Journal article
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
DOI: 10.1182/blood.20200101672020
Journal article
Cotargeting BCL-2 and MCL-1 in high-risk B-ALL
DOI: 10.1182/bloodadvances.2019001416
RECENT SCHOLARLY WORKS
2025
Journal article
Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins
DOI: 10.1038/s41418-025-01487-72025
Journal article
Acquired BCL2 variants associated with venetoclax resistance in acute myeloid leukemia
DOI: 10.1182/bloodadvances.20240144462024
Journal article
Venetoclax dose escalation rapidly activates a BAFF/BCL-2 survival axis in chronic lymphocytic leukemia
DOI: 10.1182/blood.20240243412023
Journal article
Mitochondrial E3 ubiquitin ligase MARCHF5 controls BAK apoptotic activity independently of BH3-only proteins
DOI: 10.1038/s41418-022-01067-z2022
Journal article
What Next for Singlet Fission in Photovoltaics? the Fate of Triplet and Triplet-Pair Excitons
DOI: 10.1021/acs.jpcc.2c002732022
Journal article
Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death
DOI: 10.1158/2159-8290.CD-21-05222021
Journal article
PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling
DOI: 10.1186/s13073-021-00871-5