Prof Peter Crouch
Professorial Fellow
Department of Anatomy and Physiology
145 Scholarly works
43 Projects
HIGHLIGHTS
2026
Journal article
Decreased metallothionein-3 expression in the human spinal cord is a common feature of amyotrophic lateral sclerosis and multiple sclerosis
DOI: 10.1038/s41598-025-31283-92025
Journal article
The structure, redox chemistry and motor neuron toxicity of heterodimeric zinc-deficient SOD1-implications for the toxic gain of function observed in ALS
DOI: 10.1016/j.nbd.2025.1071892025
Journal article
MDS BIOLOGY AND PATHOGENESIS - IMMUNE DEREGULATION / INFLAMMATION
DOI: 10.1016/j.leukres.2025.1078682025
Journal article
A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis
DOI: 10.1016/j.ebiom.2025.1056922023
Research grants (ARC, NHMRC, MRFF)
Muscle-Directed Gene Therapy as an Adjuvant to Neuroprotection: Targeting Both Ends of the Dysfunctional Nerve-Muscle Axis to Treat Motor Neurone Disease
2023
Research grants (ARC, NHMRC, MRFF)
Improving CNS Copper Availability to Protect Neurones and Mitigate Permanent Neurological Disability in Progressive Cases of Multiple Sclerosis
2017
Research Grant
Targeting a Deregulated Copper-Iron Axis to Treat Sporadic Mnd: A Combination Treatment Strategy
RECENT SCHOLARLY WORKS
2025
Journal article
Parkinson-like wild-type superoxide dismutase 1 pathology induces nigral dopamine neuron degeneration in a novel murine model
DOI: 10.1007/s00401-025-02859-62024
Journal article
Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS
DOI: 10.1038/s41598-024-55832-w2024
Journal article
Integrated elemental analysis supports targeting copper perturbations as a therapeutic strategy in multiple sclerosis
DOI: 10.1016/j.neurot.2024.e004322024
Journal article
Decreased spinal cord motor neuron numbers in mice depleted of central nervous system copper
DOI: 10.1093/mtomcs/mfae0362024
Journal article
Characterization of the skeletal muscle arginine methylome in health and disease reveals remodeling in amyotrophic lateral sclerosis
DOI: 10.1096/fj.202400045R2024
Journal article
Microglial ferroptotic stress causes non-cell autonomous neuronal death
DOI: 10.1186/s13024-023-00691-8
RECENT PROJECTS
2023
Research Grant
Muscle-Directed Gene Therapy as an Adjuvant to Neuroprotection: Targeting Both Ends of the Dysfunctional Nerve-Muscle Axis to Treat Motor Neurone Disease
2023
Research grants (other domestic)
A Blood-Brain Barrier Permeable DHODH Inhibitor for Treating ALS