Dr Con Panousis
Honorary Senior Fellow
Faculty of Science
49 Scholarly works
0 Projects
HIGHLIGHTS
2024
Journal article
A mechanistic model of in vitro plasma activation to evaluate therapeutic kallikrein-kinin system inhibitors
DOI: 10.1371/journal.pcbi.10125522024
Journal article
Structural basis for the inhibition of βFXIIa by garadacimab
DOI: 10.1016/j.str.2024.07.0012024
Conference Proceedings
Factor XII Deregulates Cell Communication and Contributes to Progression of Lung Fibrosis
DOI: 10.1183/13993003.congress-2024.pa42452023
Journal article
Activated Coagulation FXII: A Unique Target for in Vivo Molecular Imaging
DOI: 10.1161/ATVBAHA.122.3188832023
Journal article
High-Throughput IgG Reformatting and Expression Using Hybrid Secretion Signals and InTag Positive Selection Technology
DOI: 10.1007/978-1-0716-3381-6_232023
Journal article
HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure
DOI: 10.1080/19420862.2022.21634592022
Journal article
Evaluation of Phage Display Biopanning Strategies for the Selection of Anti-Cell Surface Receptor Antibodies
DOI: 10.3390/ijms23158470
RECENT SCHOLARLY WORKS
2022
Journal article
A phase I, first-in-human, randomized dose-escalation study of anti-activated factor XII monoclonal antibody garadacimab
DOI: 10.1111/cts.131802022
Journal article
Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques
DOI: 10.1055/a-1663-82082022
Journal article
Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?
DOI: 10.1152/AJPLUNG.00165.2021