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Email

panousis@unimelb.edu.au

Credentials


Position
Honorary Senior Fellow
Faculty of Science - Centres and Institutes

Dr Con Panousis

Honorary Senior Fellow
Faculty of Science

49 Scholarly works
0 Projects

HIGHLIGHTS

  • 2024

    Journal article

    A mechanistic model of in vitro plasma activation to evaluate therapeutic kallikrein-kinin system inhibitors
    DOI: 10.1371/journal.pcbi.1012552
  • 2024

    Journal article

    Structural basis for the inhibition of βFXIIa by garadacimab
    DOI: 10.1016/j.str.2024.07.001
  • 2024

    Conference Proceedings

    Factor XII Deregulates Cell Communication and Contributes to Progression of Lung Fibrosis
    DOI: 10.1183/13993003.congress-2024.pa4245
  • 2023

    Journal article

    Activated Coagulation FXII: A Unique Target for in Vivo Molecular Imaging
    DOI: 10.1161/ATVBAHA.122.318883
  • 2023

    Journal article

    High-Throughput IgG Reformatting and Expression Using Hybrid Secretion Signals and InTag Positive Selection Technology
    DOI: 10.1007/978-1-0716-3381-6_23
  • 2023

    Journal article

    HDX-MS study on garadacimab binding to activated FXII reveals potential binding interfaces through differential solvent exposure
    DOI: 10.1080/19420862.2022.2163459
  • 2022

    Journal article

    Evaluation of Phage Display Biopanning Strategies for the Selection of Anti-Cell Surface Receptor Antibodies
    DOI: 10.3390/ijms23158470
Con Panousis

RECENT SCHOLARLY WORKS

  • 2022

    Journal article

    A phase I, first-in-human, randomized dose-escalation study of anti-activated factor XII monoclonal antibody garadacimab
    DOI: 10.1111/cts.13180
  • 2022

    Journal article

    Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques
    DOI: 10.1055/a-1663-8208
  • 2022

    Journal article

    Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?
    DOI: 10.1152/AJPLUNG.00165.2021

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