Prof Lachlan Thompson
Honorary Professorial Fellow
Florey Department of Neuroscience and Mental Health
112 Scholarly works
11 Projects
HIGHLIGHTS
2025
Journal article
Dopamine and cortical neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction
DOI: 10.1038/s41531-025-01048-22025
Journal article
PARKIN protein-deficient iPSC line (FINi006-A) from an early-onset Parkinson's disease female patient
DOI: 10.1016/j.scr.2025.1037952025
Journal article
A pharmacological vasoconstrictor cocktail targeting endothelin signalling generates a stable, reproducible focal cerebral infarct with associated functional deficits in mice
DOI: 10.1016/j.expneurol.2025.1152152025
Journal article
Exercise promotes the functional integration of human stem cell-derived neural grafts in a rodent model of Parkinson's disease
DOI: 10.1016/j.stemcr.2025.1024802022
Research grants (ARC, NHMRC, MRFF)
Necessary Steps to Advance a Pluripotent Stem Cell-Derived Tissue Repair Therapy to the Clinic for Stroke
2021
Research Grant
In Vivo Approach to Elucidate the Pathobiology of Parkinson's-Associated Genes Using Human Diseased Neurons
2020
Research Grant
Next Generation Stem Cell Therapy for Parkinson's Disease
RECENT SCHOLARLY WORKS
2025
Journal article
A cloaked human stem-cell-derived neural graft capable of functional integration and immune evasion in rodent models
DOI: 10.1016/j.stem.2025.03.0082024
Journal article
State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons
DOI: 10.3390/biology130906902023
Journal article
Generation of the iPSC line FINi002-A from a male Parkinson's disease patient carrying compound heterozygous mutations in the PRKN gene
DOI: 10.1016/j.scr.2023.1032112023
Journal article
Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands
DOI: 10.1038/s41467-023-36133-82023
Journal article
A Selective, Hydrogel-Based Prodrug Delivery System Efficiently Activates a Suicide Gene to Remove Undifferentiated Human Stem Cells Within Neural Grafts
DOI: 10.1002/adfm.2023057712023
Journal article
Understanding and modeling regional specification of the human ganglionic eminence
DOI: 10.1016/j.stemcr.2023.01.010
RECENT PROJECTS
2021
Research grants (other domestic)
Subpial Spinal Cord Delivery as a Stem Cell-Based Treatment for MND
2021
Research Grant
Nanoparticle-Mediated Gene Delivery of Frataxin to Neurons