Prof Lachlan Thompson
Honorary Professorial Fellow
Florey Department of Neuroscience and Mental Health
115 Scholarly works
11 Projects
HIGHLIGHTS
2026
Journal article
Transgenic A53T Mice Have Astrocytic α-Synuclein Aggregates in Dopamine and Striatal Regions
DOI: 10.1111/nan.700972026
Journal article
Machine learning image analysis predicts Parkinson disease genotype and mitochondrial lysosomal abnormalities in iPS neurons
DOI: 10.1038/s41531-026-01458-w2026
Journal article
Quantitative susceptibility mapping demonstrates ageing-related long-term structural brain changes in adult rats after mild ischaemic stroke
DOI: 10.1093/braincomms/fcag1822025
Journal article
Dopamine and cortical neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction
DOI: 10.1038/s41531-025-01048-22022
Research grants (ARC, NHMRC, MRFF)
Necessary Steps to Advance a Pluripotent Stem Cell-Derived Tissue Repair Therapy to the Clinic for Stroke
2021
Research Grant
In Vivo Approach to Elucidate the Pathobiology of Parkinson's-Associated Genes Using Human Diseased Neurons
2020
Research Grant
Next Generation Stem Cell Therapy for Parkinson's Disease
RECENT SCHOLARLY WORKS
2025
Journal article
PARKIN protein-deficient iPSC line (FINi006-A) from an early-onset Parkinson's disease female patient
DOI: 10.1016/j.scr.2025.1037952025
Journal article
A pharmacological vasoconstrictor cocktail targeting endothelin signalling generates a stable, reproducible focal cerebral infarct with associated functional deficits in mice
DOI: 10.1016/j.expneurol.2025.1152152025
Journal article
Exercise promotes the functional integration of human stem cell-derived neural grafts in a rodent model of Parkinson's disease
DOI: 10.1016/j.stemcr.2025.1024802025
Journal article
A cloaked human stem-cell-derived neural graft capable of functional integration and immune evasion in rodent models
DOI: 10.1016/j.stem.2025.03.0082024
Journal article
State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons
DOI: 10.3390/biology130906902023
Journal article
Generation of the iPSC line FINi002-A from a male Parkinson's disease patient carrying compound heterozygous mutations in the PRKN gene
DOI: 10.1016/j.scr.2023.103211
RECENT PROJECTS
2021
Research grants (other domestic)
Subpial Spinal Cord Delivery as a Stem Cell-Based Treatment for MND
2021
Research Grant
Nanoparticle-Mediated Gene Delivery of Frataxin to Neurons