Prof Ricky Johnstone
Head of Department
The Sir Peter MacCallum Department of Oncology
385 Scholarly works
42 Projects
HIGHLIGHTS
2026
Journal article
Dual Bcl-2/Bcl-xl inhibition via AZD0466 combines with immune checkpoint blockade to enhance anti-tumour activity
DOI: 10.1038/s41419-025-08354-w2026
Journal article
A guide to transcriptional cyclin-dependent kinases in cancer.
DOI: 10.1111/febs.707312026
Journal article
Sensitivity of pancreatic adenocarcinoma cells to blockade of post-initiation CDK-dependent Pol II transcription cycle checkpoints.
DOI: 10.1158/1535-7163.MCT-25-15292023
Research grants (ARC, NHMRC, MRFF)
Deregulated Epigenetics and Transcription in Cancer
2018
Research Grant
Immunobiology and Immunotherapy of Cancer
2017
Research Grant
Acrf Tumour Heterogeneity Program
2014
Journal article
Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis
DOI: 10.1158/2159-8290.CD-13-0440
RECENT SCHOLARLY WORKS
2026
Journal article
Abstract B047: dCBP-30: A rationally designed, orally bioavailable, near-linkerless PROTAC for potent CBP/p300 degradation
DOI: 10.1158/1557-3265.d32026-b0472026
Journal article
An orally active dual CBP/p300 degrader targets core dependencies of multiple myeloma
DOI: 10.1016/j.celrep.2026.1174642026
Journal article
Enhanced efficacy of a specific HDAC3 inhibitor in combination with 5-azacitidine against diffuse large B-cell lymphoma
DOI: 10.1016/j.bneo.2026.1002142026
Journal article
Abstract LB476: Combined inhibition of transcription initiation and histone deacetylation triggers blood cancer cell death
DOI: 10.1158/1538-7445.am2026-lb4762026
Journal article
Discovery and Characterization of VPRBP/DCAF1 Kinase Inhibitor Analogs as Microtubular Destabilizing Agents with Potent Antimyeloma Activity
DOI: 10.1158/1535-7163.MCT-25-03062026
Journal article
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
DOI: 10.1016/j.cell.2025.10.0282025
Conference Proceedings
P300/CBP acetyltransferase inhibition and degradation disrupt oncogenic transcriptional programs and reveal epigenetic vulnerabilities in multiple myeloma
DOI: 10.1182/blood-2025-5717
RECENT PROJECTS
2024
Research grants (international)
Multi-Point Targeting of Gene Expression Regulatory Cycles as an Anticancer Therapeutic Strategy