Prof Scott Ayton
Professorial Fellow, Neuroscience
Florey Department of Neuroscience and Mental Health
203 Scholarly works
12 Projects
HIGHLIGHTS
2026
Journal article
Sodium ascorbate versus ascorbic acid in sepsis: a narrative review of emerging cardiovascular and neurological benefits
DOI: 10.1186/s13054-025-05831-82026
Journal article
Intravenous megadose sodium ascorbate normalises elevations in intracranial pressure and restores pressor responsiveness to norepinephrine in ovine Gram-negative sepsis.
DOI: 10.1038/s41598-026-59679-12026
Journal article
Ferroptosis susceptibility in hippocampal neural precursor cells influences neurogenesis and memory across aging
DOI: 10.1016/j.stem.2026.04.0172026
Journal article
Cobalt and titanium levels in the brain are associated with Alzheimer’s disease pathology but not cognition: A study of older adults with and without total joint replacement
DOI: 10.1016/j.actbio.2026.05.0062025
Research grants (ARC, NHMRC, MRFF)
MEGA-dose Sodium Ascorbate to Reduce Brain and Kidney Injury Arising From HEART Surgery (MEGA-HEART)
2022
Research grants (ARC, NHMRC, MRFF)
Translating Novel Mechanism-Guided Therapeutics to Improve Functional Recovery of the Brain and Kidneys After Open-Heart Surgery
2022
Research grants (ARC, NHMRC, MRFF)
Investigating New Targets and Treatments for Alzheimer's Disease: From Biochemistry Through to Clinical Trial
RECENT SCHOLARLY WORKS
2026
Journal article
Ferroptotic neurodegeneration and diet: a narrative review
DOI: 10.1002/alz.713682026
Journal article
Iron Depletion in the Substantia Nigra of Children With Prenatal Alcohol Exposure
DOI: 10.1111/jnc.703902026
Journal article
A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis
DOI: 10.1016/j.cell.2025.11.0142026
Journal article
Lumbar Microdiscectomy and Post-operative Activity Restrictions: A Randomised Controlled Trial
DOI: 10.1097/BRS.00000000000057202026
Journal article
Missing tissue, missing data: Resolving brain volume loss caused by anti-amyloid therapies
DOI: 10.1371/journal.pmed.10048802025
Journal article
Iron on trial: recasting the role of iron in neurodegeneration
DOI: 10.1093/brain/awaf398
RECENT PROJECTS
2024
Research grants (other domestic)
Phosphometabolomics to Investigate Protective Diets in Alzheimer\2019s Brains.
2023
Research grants (ARC, NHMRC, MRFF)
Novel Therapeutic Strategies to Intervene in Tau-Associated Neurodegeneration by Modulating Tau Clearance and Neuroinflammation