Prof David Ascher
Honorary (Professorial Fellow)
Baker Department of Cardiometabolic Health
233 Scholarly works
6 Projects
HIGHLIGHTS
2026
Journal article
A reproducible nine-step protocol for fine-tuning large language models on heterogeneous bioinformatics knowledge sources
DOI: 10.1016/j.ailsci.2026.1001792026
Journal article
mCSM-metal: A Deep Learning Resource to Predict Effect of Mutations on Metal Ion Binding
DOI: 10.1016/j.jmb.2026.1696782026
Journal article
Tracking breast cancer progression using Methylscape.
DOI: 10.1126/sciadv.aeb65562020
Research Grant
Using Protein Structure to Combat Antimicrobial Resistance
2019
Research grants (other domestic)
ACRF Facility for Innovative Cancer Drug Discovery
2018
Journal article
Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam
DOI: 10.1038/s41588-018-0117-92016
Research Grant
Understanding the Molecular Mechanisms of Complex Mutations
RECENT SCHOLARLY WORKS
2026
Journal article
Penicillin-resistant Streptococcus dysgalactiae subsp. equisimilis and the association with penicillin-binding protein mutations: a population genotypic and phenotypic study.
DOI: 10.1128/aac.00137-262026
Journal article
SGGly: a web server for whole-protein, structure-guided analysis of candidate N-linked glycosylation sites
DOI: 10.1093/nar/gkag5072026
Journal article
G2DR: a genotype-first framework for genetics-informed target prioritization and drug repurposing
DOI: 10.1093/bib/bbag4272026
Journal article
A three generation family with VACTERL association is found to have a rare form of diamond-blackfan anaemia
DOI: 10.1038/s41431-026-02076-z2026
Journal article
Transformers as a substrate for structural biology
DOI: 10.1016/j.sbi.2025.1032182026
Journal article
Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK biobank
DOI: 10.1016/j.isci.2025.1143162026
Journal article
kinCSM-RTK: Machine Learning-Based Screening of Receptor Tyrosine Kinase Inhibitors in Drug Discovery
DOI: 10.1021/acs.jcim.5c01677
RECENT PROJECTS
2020
Internal Research Grant
Structure Guided Mapping of Protein Interactions and Their Perturbation