Prof David Ascher
Honorary (Professorial Fellow)
Baker Department of Cardiometabolic Health
228 Scholarly works
6 Projects
HIGHLIGHTS
2026
Journal article
Transformers as a substrate for structural biology
DOI: 10.1016/j.sbi.2025.1032182026
Journal article
Structome-TM: Complementing dataset assembly for structural phylogenetics by addressing size-based biases
DOI: 10.1093/bioadv/vbag0352026
Journal article
Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK biobank
DOI: 10.1016/j.isci.2025.1143162020
Research Grant
Using Protein Structure to Combat Antimicrobial Resistance
2019
Research grants (other domestic)
ACRF Facility for Innovative Cancer Drug Discovery
2018
Journal article
Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam
DOI: 10.1038/s41588-018-0117-92016
Research Grant
Understanding the Molecular Mechanisms of Complex Mutations
RECENT SCHOLARLY WORKS
2026
Journal article
kinCSM-RTK: Machine Learning-Based Screening of Receptor Tyrosine Kinase Inhibitors in Drug Discovery
DOI: 10.1021/acs.jcim.5c016772026
Journal article
A three generation family with VACTERL association is found to have a rare form of diamond-blackfan anaemia
DOI: 10.1038/s41431-026-02076-z2026
Journal article
mCSM-metal: A Deep Learning Resource to Predict Effect of Mutations on Metal Ion Binding
DOI: 10.1016/j.jmb.2026.1696782026
Journal article
Systematic evaluation of computational tools to predict the effects of mutations on protein-ligand binding affinity in the absence of experimental structures
DOI: 10.1093/bib/bbag0352026
Journal article
Structome-AlignViewer: On Confidence Assessment in Structure-Aware Alignments
DOI: 10.1093/gbe/evag0042025
Journal article
Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites
DOI: 10.1038/s41467-025-57405-52025
Journal article
Combinatorial Discovery of RAFT Cationic Polymers for mRNA Delivery: Structure–Function Insights from High-Throughput Screening and Machine Learning
DOI: 10.1021/acs.biomac.5c01236
RECENT PROJECTS
2020
Internal Research Grant
Structure Guided Mapping of Protein Interactions and Their Perturbation