Prof Phillip Darcy
Honorary Conjoint Professorial Fellow
The Sir Peter MacCallum Department of Oncology
292 Scholarly works
44 Projects
HIGHLIGHTS
2026
Journal article
The genome takes the wheel: CAR T with built-in circuits
DOI: 10.1016/j.iotech.2026.1015972026
Journal article
ENHANCING CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY FOR PAEDIATRIC SARCOMA THROUGH CAR T ENGINEERING AND TUMOUR MICROENVIRONMENT REWIRING
DOI: 10.1016/j.jcyt.2026.1022252026
Journal article
Cytokine armored CAR T cells for cancer immunotherapy
DOI: 10.1111/imcb.701122026
Journal article
Auto-inducible expression of chimeric antigen receptor T cells using the NR4A1 promoter
DOI: 10.1111/imcb.700952024
Research grants (ARC, NHMRC, MRFF)
Development of New Strategies for Enhancing CAR T Cell Therapy of Cancer
2024
Research grants (ARC, NHMRC, MRFF)
An Integrated Approach to CAR-T Cell Therapy in Prostate Cancer
2018
Research Grant
Immunobiology and Immunotherapy of Cancer
RECENT SCHOLARLY WORKS
2026
Journal article
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8 T cells in lymph nodes
DOI: 10.1038/s41590-026-02419-42026
Journal article
Parity and lactation induce T-cell-mediated breast cancer protection
DOI: 10.1038/s41586-025-09713-52026
Journal article
Refuel and endure: improving metabolic fitness and efficacy in CAR-T therapy
DOI: 10.1016/j.iotech.2026.1015832025
Journal article
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
DOI: 10.1038/s41467-025-59021-92025
Journal article
Transcriptional regulator SATB1 limits CD8 T cell population expansion and effector differentiation in chronic infection and cancer
DOI: 10.1038/s41590-025-02316-22025
Conference Proceedings
297 Identifying optimal tumour-specific genes for CRISPR/Cas9 engineering of armoured CAR T cells with enhanced safety and efficacy
DOI: 10.1136/jitc-2025-sitc2025.0297
RECENT PROJECTS
2026
Research grants (other domestic)
Reprogramming CAR T Cells for Enhancing Persistence and Efficacy Against Solid Cancers
2024
Research grants (other domestic)
New Frontiers for CAR T Cell Therapy in Breast Cancer