Prof Phillip Darcy
Honorary Conjoint Professorial Fellow
The Sir Peter MacCallum Department of Oncology
186 Scholarly works
35 Projects
HIGHLIGHTS
2026
Journal article
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8 T cells in lymph nodes
DOI: 10.1038/s41590-026-02419-42026
Journal article
Parity and lactation induce T-cell-mediated breast cancer protection
DOI: 10.1038/s41586-025-09713-52026
Journal article
Refuel and endure: improving metabolic fitness and efficacy in CAR-T therapy
DOI: 10.1016/j.iotech.2026.1015832025
Journal article
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
DOI: 10.1038/s41467-025-59021-92024
Research grants (ARC, NHMRC, MRFF)
Development of New Strategies for Enhancing CAR T Cell Therapy of Cancer
2018
Research Grant
Immunobiology and Immunotherapy of Cancer
2017
Research Grant
Exploiting and Defining the Immune Regulatory Activities of Bet Bromodomain Inhibitors
RECENT SCHOLARLY WORKS
2025
Journal article
Transcriptional regulator SATB1 limits CD8 T cell population expansion and effector differentiation in chronic infection and cancer
DOI: 10.1038/s41590-025-02316-22025
Journal article
A novel switch receptor enhances CAR-T cell fitness in TGF-β-enriched solid tumors 3396
DOI: 10.1093/jimmun/vkaf283.12072025
Journal article
3208O Parity and breastfeeding enhance breast resident CD8 T cell immunity and protect against breast cancer
DOI: 10.1016/j.annonc.2025.08.7532025
Journal article
Optimised modular anti-FLAG CAR T cells for solid tumor therapy
DOI: 10.1002/cti2.700462025
Journal article
Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
DOI: 10.1038/s41586-025-09212-72025
Journal article
27P CAR-T cells secreting tumour-specific bispecific engagers for solid tumour treatment
DOI: 10.1016/j.esmoop.2025.105374
RECENT PROJECTS
2026
Research grants (other domestic)
Reprogramming CAR T Cells for Enhancing Persistence and Efficacy Against Solid Cancers
2024
Research grants (other domestic)
New Frontiers for CAR T Cell Therapy in Breast Cancer