Dr Eric Joo
Senior Research Fellow in Molecular Biology
Department of Clinical Pathology
118 Scholarly works
6 Projects
HIGHLIGHTS
2026
Journal article
Lynch syndrome caused by a pathogenic SINE-VNTR-Alu (SVA) insertion in MSH2 gene identified by long-read DNA sequencing
DOI: 10.1007/s10689-026-00588-72026
Journal article
Germline MLH1 c.-42 C > T is a likely pathogenic variant predisposing to a reduced-penetrance/modified Lynch syndrome phenotype featuring MLH1-methylated cancers
DOI: 10.1007/s10689-025-00519-y2025
Journal article
Abstract PR004: Mutational signature profiling identifies a distinct subgroup of early-onset colorectal cancer associated with younger age at diagnosis, recent birth year and specific genomic features
DOI: 10.1158/1557-3265.earlyonsetca25-pr0042025
Journal article
Abstract C014: Unexplained familial early-onset colorectal cancer: Determining a shared etiology by tumor mutational signature profiling
DOI: 10.1158/1557-3265.earlyonsetca25-c0142025
Research grants (other domestic)
Preventing Colorectal Cancer Caused by Gut Bacteria
2022
Research grants (other domestic)
Linking Gut Bacteria to the Development of Early Onset Colorectal Cancer Using Multi-Omic Profiling
2019
Research Grant
Heritable Methylation Marks Associated With Colorectal Cancer Risk
RECENT SCHOLARLY WORKS
2025
Journal article
Abstract C020: Novel insights from the investigation of experimental mutational signatures in early-onset colorectal cancer and colonic polyps
DOI: 10.1158/1557-3265.earlyonsetca25-c0202025
Journal article
Abstract C021: Characterizing the clinicopathological, genomic and spatial transcriptomic features of colibactin-induced colorectal cancers
DOI: 10.1158/1557-3265.earlyonsetca25-c0212025
Journal article
The germline POLD1 c.1420 C > A (p.Leu474Ile) variant segregates with endometrial cancer, colorectal cancer and colonic polyps demonstrating hypermutation and defective POLD1 mutational signatures
DOI: 10.1007/s10689-025-00506-32025
Journal article
Genetics, genomics and clinical features of adenomatous polyposis
DOI: 10.1007/s10689-025-00460-02025
Journal article
DNA Mismatch Repair Gene Mosaicism Is Rare in People With Mismatch Repair-Deficient Cancers
DOI: 10.1053/j.gastro.2024.12.0272025
Journal article
Intratumoural pks Escherichia coli is associated with risk of metachronous colorectal cancer and adenoma development in people with Lynch syndrome
DOI: 10.1016/j.ebiom.2025.105661
RECENT PROJECTS
2017
Research Grant
Heritable Epigenetic Risk Factors for Prostate Cancer.
2015
Research Grant
A Prospective Study of the Influence of Health - Related Lifestyle Factors on Dna Methylation