Prof Ilia Voskoboinik
Honorary Conjoint Professorial Fellow
The Sir Peter MacCallum Department of Oncology
27 Scholarly works
6 Projects
HIGHLIGHTS
2025
Journal article
Partial STX11 deficiency due to a hypomorphic variant—self-limiting inflammatory disease preceding HLH onset
DOI: 10.70962/jhi.202501002025
Journal article
Acidic pH can attenuate immune killing through inactivation of perforin
DOI: 10.1038/s44319-024-00365-62024
Journal article
Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing
DOI: 10.1038/s41594-024-01336-02024
Journal article
Early hematopoietic cell transplantation for familial hemophagocytic lymphohistiocytosis in a regional treatment network in Japan
DOI: 10.1007/s12185-024-03721-32018
Research Grant
Novel Therapies to Enhance Anti-Tumour Immunity
2017
Research Grant
The Biogenesis of Cytotoxic Granules
2017
Research Grant
The Anti-Cancer Potential of Human Gamma Delta T Cells
RECENT SCHOLARLY WORKS
2024
Journal article
Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells
DOI: 10.3389/fphar.2024.13967102023
Journal article
Fragment-based and structure-guided discovery of perforin inhibitors
DOI: 10.1016/j.ejmech.2023.1157862022
Journal article
Small Molecule Inhibitors of Lymphocyte Perforin as Focused Immunosuppressants for Infection and Autoimmunity
DOI: 10.1021/acs.jmedchem.2c013382022
Journal article
Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick disease type C1
DOI: 10.1182/blood.20210134772022
Journal article
The pore conformation of lymphocyte perforin
DOI: 10.1126/sciadv.abk31472021
Journal article
Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance
DOI: 10.1038/s41467-021-24577-9
RECENT PROJECTS
2014
Research Grant
How the Immune System Controls Viral Infections and Cancer
2016
Research Grant
Structural Studies on the Immune Effector Perforin: Developing Mechanism-Based Inhibitors