Dr Toby Phesse
Honorary (Senior Fellow)
Department of Infectious Diseases
27 Scholarly works
2 Projects
HIGHLIGHTS
2021
Book Chapter
Frizzled7 Activates β-Catenin-Dependent and β-Catenin-Independent Wnt Signalling Pathways During Developmental Morphogenesis: Implications for Therapeutic Targeting in Colorectal Cancer
DOI: 10.1007/164_2021_5242020
Journal article
Mesenchymal niche-derived Neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium
DOI: 10.1016/j.stem.2020.06.0212020
Journal article
The hepatitis B virus pre-core protein P22 activates Wnt signaling
DOI: 10.3390/cancers120614352020
Journal article
Targeting wnt signaling for the treatment of gastric cancer
DOI: 10.3390/ijms211139272019
Journal article
Frizzled-7 is required for Wnt signaling in gastric tumors with and without APC mutations
DOI: 10.1158/0008-5472.CAN-18-20952018
Journal article
Wnt signalling in gastrointestinal epithelial stem cells
DOI: 10.3390/genes90401782014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2018
Journal article
Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells
DOI: 10.1002/dvdy.245272018
Journal article
The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy
DOI: 10.1016/bs.pmbts.2017.11.0092017
Journal article
Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers
DOI: 10.1111/bph.138902017
Journal article
Defining key concepts of intestinal and epithelial cancer biology through the use of mouse models
DOI: 10.1093/carcin/bgx080
RECENT PROJECTS
2016
Research Grant
Fzd7 as a Therapeutic Target for Gastric Cancer
2012
Research Grant
Frizzled Function in the Intestinal Crypt and Adenoma Formation