Prof James Murphy
Honorary (Professorial Fellow)
Department of Medical Biology (WEHI)
223 Scholarly works
2 Projects
HIGHLIGHTS
2026
Journal article
Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy
DOI: 10.1038/s41467-026-70133-82026
Journal article
Impact of BECLIN1 haploinsufficiency on goblet cell function and susceptibility to colitis
DOI: 10.1038/s41419-026-08984-82026
Journal article
SMCHD1 is a target for gene activation therapy to treat Prader-Willi syndrome.
DOI: 10.1126/sciadv.aej57022026
Journal article
IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial
DOI: 10.1038/s41467-026-77552-72026
Research contracts (non-grants)
Necroptosis in Kidney Transplantation
2024
Research grants (other domestic)
Shedding Light, and Electrons, on MLKL Oligomerisation Within Native Cell Membranes
2014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2026
Journal article
A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
DOI: 10.1126/science.aeh71122026
Journal article
An Ancestral Mechanism of Calmodulin Binding to Cds1 Kinase Inhibits Catalytic Activity
DOI: 10.1002/iub.701282026
Journal article
Black Sheep: Pseudokinases Bucking the Trend to Reveal Non-Catalytic Kinase Functions
DOI: 10.1002/iub.701252026
Journal article
The kinase domain of RIPK3 tunes its scaffolding functions
DOI: 10.1038/s41418-026-01677-x2026
Journal article
Low Agonism and Balanced Pathway Modulation Distinguish an M1 Muscarinic Receptor Positive Allosteric Modulator Lacking Cholinergic Adverse Effects
DOI: 10.1021/acschemneuro.6c002292026
Journal article
The multifaceted roles of receptor tyrosine pseudokinases in cellular signalling
DOI: 10.1042/BST20260770