Prof James Murphy
Honorary (Professorial Fellow)
Department of Medical Biology (WEHI)
213 Scholarly works
2 Projects
HIGHLIGHTS
2026
Journal article
Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy
DOI: 10.1038/s41467-026-70133-82026
Journal article
Impact of BECLIN1 haploinsufficiency on goblet cell function and susceptibility to colitis
DOI: 10.1038/s41419-026-08984-82026
Journal article
Low Agonism and Balanced Pathway Modulation Distinguish an M1 Muscarinic Receptor Positive Allosteric Modulator Lacking Cholinergic Adverse Effects
DOI: 10.1021/acschemneuro.6c002292026
Journal article
The multifaceted roles of receptor tyrosine pseudokinases in cellular signalling
DOI: 10.1042/BST202607702026
Research contracts (non-grants)
Necroptosis in Kidney Transplantation
2024
Research grants (other domestic)
Shedding Light, and Electrons, on MLKL Oligomerisation Within Native Cell Membranes
2014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2026
Journal article
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
DOI: 10.1016/j.chembiol.2026.03.0052026
Journal article
Inspiring discovery through reviews and visualization in biochemistry
DOI: 10.1016/j.tibs.2026.01.0092026
Journal article
The kinase domain of RIPK3 tunes its scaffolding functions
DOI: 10.1038/s41418-026-01677-x2025
Journal article
Lipid nanoparticle-delivered intrabodies for inhibiting necroptosis and pyroptosis
DOI: 10.1042/bcj202531912025
Journal article
PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2 sensor proteins
DOI: 10.1073/pnas.24209611222025
Journal article
Protein shapeshifting in necroptotic cell death signaling
DOI: 10.1016/j.tibs.2024.11.006