Prof James Murphy
Honorary (Professorial Fellow)
Department of Medical Biology (WEHI)
212 Scholarly works
1 Projects
HIGHLIGHTS
2026
Journal article
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
DOI: 10.1016/j.chembiol.2026.03.0052026
Journal article
Inspiring discovery through reviews and visualization in biochemistry
DOI: 10.1016/j.tibs.2026.01.0092026
Journal article
Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy.
DOI: 10.1038/s41467-026-70133-82026
Journal article
The kinase domain of RIPK3 tunes its scaffolding functions
DOI: 10.1038/s41418-026-01677-x2025
Journal article
Lipid nanoparticle-delivered intrabodies for inhibiting necroptosis and pyroptosis
DOI: 10.1042/bcj202531912024
Research grants (other domestic)
Shedding Light, and Electrons, on MLKL Oligomerisation Within Native Cell Membranes
2014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2025
Journal article
PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2 sensor proteins
DOI: 10.1073/pnas.24209611222025
Journal article
Protein shapeshifting in necroptotic cell death signaling
DOI: 10.1016/j.tibs.2024.11.0062025
Journal article
Inhibition of RIPK1 or RIPK3 kinase activity post ischemia-reperfusion reduces the development of chronic kidney injury
DOI: 10.1042/BCJ202405692025
Journal article
Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity
DOI: 10.1042/BCJ202534312025
Journal article
Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice
DOI: 10.26508/lsa.202302446