A/Prof. Grant Dewson
Honorary
Medical Biology (W.E.H.I.)
81 Scholarly works
0 Projects
HIGHLIGHTS
2021
Journal article
Too much death can kill you: inhibiting intrinsic apoptosis to treat disease
DOI: 10.15252/embj.20201073412021
Journal article
Structure of detergent-activated BAK dimers derived from the inert monomer.
DOI: 10.1016/j.molcel.2021.03.0142021
Journal article
A new crystal form of GABARAPL2
DOI: 10.1107/S2053230X210044892021
Journal article
Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities
DOI: 10.1038/s41418-020-00706-72020
Journal article
BAK core dimers bind lipids and can be bridged by them
DOI: 10.1038/s41594-020-0494-52020
Journal article
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2
DOI: 10.15252/embj.20201062752020
Journal article
MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3( )regulatory T cells
DOI: 10.1038/s41418-020-0585-1
RECENT SCHOLARLY WORKS
2020
Journal article
EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins
DOI: 10.1038/s41418-019-0435-12020
Journal article
Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
DOI: 10.1038/s41419-020-2463-72019
Journal article
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
DOI: 10.1038/s41589-019-0365-82019
Journal article
BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
DOI: 10.1016/j.celrep.2019.03.0402019
Journal article
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy
DOI: 10.15252/embj.2018999162018
Journal article
VDAC2 enables BAX to mediate apoptosis and limit tumor development
DOI: 10.1038/s41467-018-07309-42018
Journal article
Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development
DOI: 10.1101/gad.314286.1182018
Journal article
Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use
DOI: 10.1182/blood-2018-06-859405