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Email

vaillant@unimelb.edu.au

Credentials


Position
Honorary (Fellow)
Department of Medical Biology (WEHI)
ORCID

0000-0003-3229-3760

Dr Francois Vaillant

Honorary (Fellow)
Department of Medical Biology (WEHI)

102 Scholarly works
0 Projects

HIGHLIGHTS

  • 2026

    Journal article

    IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
    DOI: 10.1016/j.chembiol.2026.03.005
  • 2025

    Journal article

    Fibroblast hierarchy dynamics during mammary gland morphogenesis and tumorigenesis
    DOI: 10.1038/s44318-025-00422-3
  • 2024

    Journal article

    Hormone-responsive progenitors have a unique identity and exhibit high motility during mammary morphogenesis
    DOI: 10.1016/j.celrep.2024.115073
  • 2024

    Journal article

    Ehf controls mammary alveolar lineage differentiation and is a putative suppressor of breast tumorigenesis
    DOI: 10.1016/j.devcel.2024.04.022
  • 2024

    Journal article

    Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
    DOI: 10.1158/2159-8290.CD-23-0402
  • 2024

    Journal article

    Exploring breast cancer vulnerabilities through apoptotic pathways
    DOI: 10.1158/1538-7445.ADVBC23-IA26
  • 2019

    Journal article

    A phase Ib dose-escalation and expansion study of the BCL2 inhibitor venetoclax combined with tamoxifen in ER and BCL2– positive metastatic breast cancer
    DOI: 10.1158/2159-8290.CD-18-1151
Francois Vaillant

RECENT SCHOLARLY WORKS

  • 2024

    Journal article

    Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers
    DOI: 10.1038/s41556-023-01315-5
  • 2023

    Journal article

    Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER breast cancer
    DOI: 10.1016/j.chembiol.2023.07.005
  • 2022

    Journal article

    In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis
    DOI: 10.1002/1878-0261.13179
  • 2021

    Journal article

    Single cell transcriptome atlas of mouse mammary epithelial cells across development
    DOI: 10.1186/s13058-021-01445-4

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