Prof John Silke
Honorary Professorial Fellow
Faculty of Medicine, Dentistry and Health Sciences
40 Scholarly works
0 Projects
HIGHLIGHTS
2026
Journal article
ANCHR regulates TRAIL-mediated apoptosis with implications for liver injury
DOI: 10.1016/j.heliyon.2026.e450902026
Journal article
Infection-induced glucose starvation triggers NINJ1-dependent macrophage lysis and Candida escape.
DOI: 10.1038/s41467-026-74195-62026
Journal article
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
DOI: 10.1016/j.chembiol.2026.03.0052026
Journal article
The PANoptosis hypothesis examined
DOI: 10.1038/s41580-026-00970-42024
Journal article
RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation
DOI: 10.1038/s41418-024-01281-x2024
Journal article
Mind bomb 2 limits inflammatory dermatitis in Sharpin mutant mice independently of cell death
DOI: 10.1093/pnasnexus/pgad4382014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2023
Journal article
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency
DOI: 10.15252/embj.20211104682022
Journal article
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
DOI: 10.1016/j.immuni.2022.01.0032020
Journal article
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
DOI: 10.1038/s41467-020-16819-z2020
Journal article
A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity
DOI: 10.15252/embr.202050400