Prof John Silke
Honorary (Professorial Fellow)
Department of Medical Biology (WEHI)
291 Scholarly works
1 Projects
HIGHLIGHTS
2026
Journal article
Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors
DOI: 10.1038/s42004-025-01871-x2026
Journal article
The transmembrane domain structure of TNFR1 suppresses ligand-independent autoactivation but is not required for TNF-induced signaling.
DOI: 10.1126/scisignal.adz02032026
Journal article
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
DOI: 10.1016/j.chembiol.2026.03.0052026
Journal article
The PANoptosis hypothesis examined
DOI: 10.1038/s41580-026-00970-42026
Journal article
Hemidesmosomal Proteins in Oral Cancer Progression: An Immunohistochemical Study of Human and Mouse
DOI: 10.1111/jop.701452026
Journal article
The kinase domain of RIPK3 tunes its scaffolding functions
DOI: 10.1038/s41418-026-01677-x2014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2025
Journal article
SIX of one and half-a-dozen USP2 regulating inflammation
DOI: 10.1038/s41422-025-01173-w2025
Journal article
Enabling high-resolution diagnostic oral confocal laser endomicroscopy in mice
DOI: 10.1016/j.ymeth.2025.04.0152025
Journal article
The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro
DOI: 10.26508/lsa.2025032432025
Journal article
AXIN2 is a non-redundant regulator of AXIN1 stability and β-catenin in colorectal cancer cells
DOI: 10.1111/febs.17336
RECENT PROJECTS
2016
Internal Research Grant
Targeting TWEAK/Fn14 Signalling to Treat Cardiac Cachexia in Cancer