Prof John Silke
Honorary Professorial Fellow
Faculty of Medicine, Dentistry and Health Sciences
236 Scholarly works
0 Projects
HIGHLIGHTS
2026
Journal article
The benchmarking and application of tag-degraders in vivo to validate therapeutic targets
DOI: 10.1038/s41467-026-73681-12026
Journal article
Infection-induced glucose starvation triggers NINJ1-dependent macrophage lysis and Candida escape
DOI: 10.1038/s41467-026-74195-62026
Journal article
Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors
DOI: 10.1038/s42004-025-01871-x2026
Journal article
The PANoptosis hypothesis examined
DOI: 10.1038/s41580-026-00970-42026
Journal article
Reply to ‘Single-cell evidence for PANoptosome complexes’
DOI: 10.1038/s41580-026-00995-92026
Journal article
The kinase domain of RIPK3 tunes its scaffolding functions
DOI: 10.1038/s41418-026-01677-x2014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2026
Journal article
Emerging challenges, mechanisms, and therapeutic opportunities in cell death
DOI: 10.1016/j.chembiol.2026.06.0152026
Journal article
ANCHR regulates TRAIL-mediated apoptosis with implications for liver injury
DOI: 10.1016/j.heliyon.2026.e450902026
Journal article
The transmembrane domain structure of TNFR1 suppresses ligand-independent autoactivation but is not required for TNF-induced signaling
DOI: 10.1126/scisignal.adz02032026
Journal article
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
DOI: 10.1016/j.chembiol.2026.03.005