Dr Bruce Wong
Research Fellow, Neuropharmacology
Department of Biochemistry and Pharmacology
25 Scholarly works
1 Projects
HIGHLIGHTS
2026
Research grants (other domestic)
AI-Driven Drug Discovery for Next-Generation STING Inhibitors
2024
Journal article
Pharmacological inhibition of STING reduces neuroinflammation-mediated damage post-traumatic brain injury
DOI: 10.1111/bph.163472021
Journal article
The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing
DOI: 10.1038/s41380-021-01248-12021
Journal article
Increased glutaminyl cyclase activity in brains of Alzheimer’s disease individuals
DOI: 10.1111/jnc.151142020
Journal article
Amyloidogenic processing of Alzheimer’s disease β-amyloid precursor protein induces cellular iron retention
DOI: 10.1038/s41380-020-0762-02019
Journal article
Post Translational Modulation of β-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis
DOI: 10.1007/s11064-019-02747-y2018
Journal article
Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice
DOI: 10.1007/s13311-018-0656-x
RECENT SCHOLARLY WORKS
2017
Journal article
Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta
DOI: 10.1038/s41598-017-10233-02017
Journal article
[P1–169]: LACTOFERRIN IS AN IRON TRANSPORTER AND KEY INNATE IMMUNE RESPONSE PROTEIN THAT DIRECTLY BINDS AMYLOID‐β PRECURSOR PROTEIN TO PROMOTE AMYLOIDOGENIC PROCESSING
DOI: 10.1016/j.jalz.2017.06.2362017
Journal article
[P3–153]: THE INFLUENCE OF AMYLOID‐B PRECURSOR PROTEIN PROTEOLYTIC PROCESSING ON NEURONAL IRON HOMEOSTASIS
DOI: 10.1016/j.jalz.2017.06.13652017
Journal article
Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson’s disease
DOI: 10.1186/s13024-017-0186-8