Mr Christophe Rosty
Honorary (Principal Fellow)
Department of Clinical Pathology
234 Scholarly works
3 Projects
HIGHLIGHTS
2026
Journal article
Germline MLH1 c.-42 C > T is a likely pathogenic variant predisposing to a reduced-penetrance/modified Lynch syndrome phenotype featuring MLH1-methylated cancers
DOI: 10.1007/s10689-025-00519-y2026
Journal article
Understanding heterogeneity in the pathogenesis and drug responses of ulcerative colitis through single-cell and spatial transcriptomics.
DOI: 10.3389/fimmu.2026.17942072025
Journal article
Abstract PR004: Mutational signature profiling identifies a distinct subgroup of early-onset colorectal cancer associated with younger age at diagnosis, recent birth year and specific genomic features
DOI: 10.1158/1557-3265.earlyonsetca25-pr0042025
Journal article
Abstract B017: Trends in early-onset colorectal, appendiceal, and anal tumour incidence by histological subtype in Australia from 1990 to 2020: A population-based time-series analysis
DOI: 10.1158/1557-3265.earlyonsetca25-b0172025
Journal article
Abstract C020: Novel insights from the investigation of experimental mutational signatures in early-onset colorectal cancer and colonic polyps
DOI: 10.1158/1557-3265.earlyonsetca25-c0202020
Research Grant
Why Does Colonoscopy Fail to Prevent Colon Cancer in People With Lynch Syndrome?
2018
Research grants (other domestic)
Can Genomic Profiling Help Predict Who Will Get a Second Bowel Tumour?
RECENT SCHOLARLY WORKS
2025
Journal article
Abstract C014: Unexplained familial early-onset colorectal cancer: Determining a shared etiology by tumor mutational signature profiling
DOI: 10.1158/1557-3265.earlyonsetca25-c0142025
Journal article
Abstract C021: Characterizing the clinicopathological, genomic and spatial transcriptomic features of colibactin-induced colorectal cancers
DOI: 10.1158/1557-3265.earlyonsetca25-c0212025
Journal article
The germline POLD1 c.1420 C > A (p.Leu474Ile) variant segregates with endometrial cancer, colorectal cancer and colonic polyps demonstrating hypermutation and defective POLD1 mutational signatures
DOI: 10.1007/s10689-025-00506-32025
Journal article
Age-specific trends in colorectal, appendiceal, and anal tumour incidence by histological subtype in Australia from 1990 to 2020: a population-based time-series analysis
DOI: 10.1016/j.lanwpc.2025.1017282025
Journal article
DNA Mismatch Repair Gene Mosaicism Is Rare in People With Mismatch Repair-Deficient Cancers
DOI: 10.1053/j.gastro.2024.12.027
RECENT PROJECTS
2014
Research Grant
Early Onset Colorectal Cancer