Prof. William Heath
Professor
Microbiology and Immunology
293 Scholarly works
44 Projects
HIGHLIGHTS
2021
Journal article
Elucidating the Motif for CpG Oligonucleotide Binding to the Dendritic Cell Receptor DEC-205 Leads to Improved Adjuvants for Liver-Resident Memory.
DOI: 10.4049/jimmunol.20011532021
Journal article
CD8 and CD4 T Cells Infiltrate into the Brain during Plasmodium berghei ANKA Infection and Form Long-Term Resident Memory.
DOI: 10.4049/jimmunol.20007732021
Journal article
Hemozoin-mediated inflammasome activation limits long-lived anti-malarial immunity
DOI: 10.1016/j.celrep.2021.1095862021
Research Grant
AdaptiVax-CoV: A novel adaptable SARS-CoV2 VLP vaccine to produce broad humoral and T cell responses to S, E and M viral proteins
2017
Research Grant
ANTIGEN PRESENTATION, RECOGNITION AND THE IMMUNE RESPONSE
2016
Journal article
Liver-Resident Memory CD8( ) T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection
DOI: 10.1016/j.immuni.2016.08.0112012
Research Grant
ANTIGEN PRESENTATION RECOGNITION AND THE IMMUNE SYSTEM
RECENT SCHOLARLY WORKS
2021
Journal article
Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity
DOI: 10.1038/s41590-021-01004-12021
Journal article
CD49d marks Th1 and Tfh-like antigen-specific CD4( ) T cells during Plasmodium chabaudi infection
DOI: 10.1093/intimm/dxab0202021
Journal article
Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses
DOI: 10.1016/j.immuni.2021.03.0252021
Conference Proceedings
Development of Plasmodium-specific liver-resident memory CD8( ) T cells after heat-killed sporozoite immunization in mice
DOI: 10.1002/eji.2020487572021
Journal article
High expression of CD38 and MHC class II on CD8 T cells during severe influenza disease reflects bystander activation and trogocytosis
DOI: 10.1101/2021.02.09.4304102021
Journal article
Harnessing liver-resident memory T cells for protection against malaria
DOI: 10.1080/14760584.2021.18814852021
Journal article
Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity
DOI: 10.1371/journal.ppat.1009288
RECENT PROJECTS
2020
Research Contracts
Designing a scalable vaccine to induce liver resident T cells against malaria.