Dr. Joanne Hildebrand
Honorary
Medical Biology (W.E.H.I.)
30 Scholarly works
0 Projects
HIGHLIGHTS
2021
Journal article
The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis.
DOI: 10.1038/s41419-021-03418-z2020
Journal article
Necroptotic movers and shakers: cell types, inflammatory drivers and diseases.
DOI: 10.1016/j.coi.2020.09.0082020
Journal article
Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the Pathway
DOI: 10.1021/acschembio.0c004822020
Journal article
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
DOI: 10.1038/s41467-020-16887-12020
Journal article
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
DOI: 10.1038/s41467-020-16819-z2020
Journal article
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
DOI: 10.1073/pnas.19199601172019
Journal article
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs (vol 9, pg 4457, 2018)
DOI: 10.1038/s41467-019-09536-9
RECENT SCHOLARLY WORKS
2018
Journal article
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
DOI: 10.1038/s41467-018-06985-62018
Journal article
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
DOI: 10.1038/s41467-018-04714-72018
Journal article
Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
DOI: 10.1038/s41418-017-0031-12018
Journal article
Methods for Studying TNF-Mediated Necroptosis in Cultured Cells
DOI: 10.1007/978-1-4939-8754-2_52017
Journal article
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation
DOI: 10.1038/nmicrobiol.2016.2582017
Journal article
Combination of IAP antagonist and IFN gamma activates novel caspase-10-and RIPK1-dependent cell death pathways
DOI: 10.1038/cdd.2016.1472017
Journal article
Insane in the membrane: a structural perspective of MLKL function in necroptosis
DOI: 10.1038/icb.2016.1252017
Journal article
Synaptic Zn2 and febrile seizure susceptibility
DOI: 10.1111/bph.13658