Dr James Hilton
Research Fellow
Department of Anatomy and Physiology
28 Scholarly works
6 Projects
HIGHLIGHTS
2026
Journal article
Decreased metallothionein-3 expression in the human spinal cord is a common feature of amyotrophic lateral sclerosis and multiple sclerosis
DOI: 10.1038/s41598-025-31283-92024
Journal article
Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS
DOI: 10.1038/s41598-024-55832-w2024
Journal article
Integrated elemental analysis supports targeting copper perturbations as a therapeutic strategy in multiple sclerosis
DOI: 10.1016/j.neurot.2024.e004322024
Journal article
Decreased spinal cord motor neuron numbers in mice depleted of central nervous system copper
DOI: 10.1093/mtomcs/mfae0362019
Research Grant
Understanding the Cellular Causes of Motor Neurone Disease to Progress Development of Truly Effective Therapeutics
2019
Research Grant
Ferroxidase Dysfunction Drives Glial Ferroptotic Stress and Motor Neurone Death via Neurotoxic A1 Astrocyte Conversion
2018
Research Grant
A Therapeutic Copper Compound to Treat Progressive Multiple Sclerosis
RECENT SCHOLARLY WORKS
2024
Journal article
Microglial ferroptotic stress causes non-cell autonomous neuronal death
DOI: 10.1186/s13024-023-00691-82024
Journal article
Evidence for decreased copper associated with demyelination in the corpus callosum of cuprizone-treated mice
DOI: 10.1093/mtomcs/mfad0722023
Journal article
Decay spectroscopy at the two-proton drip line: Radioactivity of the new nuclides 160Os and 156W
DOI: 10.1016/j.physletb.2023.1383102023
Journal article
Fundamental Neurochemistry Review: Copper availability as a potential therapeutic target in progressive supranuclear palsy: Insight from other neurodegenerative diseases
DOI: 10.1111/jnc.159782023
Journal article
CuII(atsm) significantly decreases microglial reactivity in patients with sporadic amyotrophic lateral sclerosis
DOI: 10.1111/nan.129382023
Journal article
Transdermal Application of Soluble CuII(atsm) Increases Brain and Spinal Cord Uptake Compared to Gavage with an Insoluble Suspension
DOI: 10.1016/j.neuroscience.2022.11.026
RECENT PROJECTS
2026
Research grants (other domestic)
Targeting Neuroprotection in Progressive Multiple Sclerosis
2018
Research Grant
A Therapeutic Copper Compound to Treat Progressive Multiple Sclerosis